Papers in Scientific Journals (25)
Carvalho D. N., Dani S., Sotelo C. G., Perez-Martin R. I., Reis R. L., Silva T. H., and Gelinsky M.,
"Assessing non-synthetic crosslinkers in biomaterial inks based on polymers of marine origin to increase the shape fidelity in 3D extrusion printing",
Biomedical Materials, vol. 18, issue 5, pp. 055017, doi:
10.1088/1748-605X/acecec, 2023.
Reys L. L., Silva S. S., Costa D., Soares da Costa D., Rodrigues, L.C., Reis R. L., and Silva T. H.,
"Building Fucoidan/Agarose-Based Hydrogels as a Platform for the Development of Therapeutic Approaches against Diabetes",
Molecules, vol. 28, pp. 4523, doi:
https://doi.org/10.3390/ molecules28114523, 2023.
Rodrigues C. V., Sousa R. O., Carvalho A. C., Alves A. L., Marques C. F., Cerqueira M. T., Reis R. L., and Silva T. H.,
"Potential of Atlantic Codfish (Gadus morhua) Skin Collagen for Skincare Biomaterials",
Molecules, vol. 28, issue 8, pp. 3394, doi:
https://doi.org/10.3390/molecules28083394, 2023.
Machado I., Marques C. F., Martins E., Alves A. L., Reis R. L., and Silva T. H.,
"Marine Gelatin-Methacryloyl-Based Hydrogels as Cell Templates for Cartilage Tissue Engineering",
Polymers, vol. 15, issue 7, pp. 1674, doi:
https://doi.org/10.3390/polym15071674, 2023.
Alves A. L., Carvalho A. C., Machado I., Diogo G. S., Fernandes E. M., Castro V. I. B., Pires R. A., Vázquez J. A., Perez-Martin R. I., Alaminos M., Reis R. L., and Silva T. H.,
"Cell-Laden Marine Gelatin Methacryloyl Hydrogels Enriched with Ascorbic Acid for Corneal Stroma Regeneration",
Bioengineering, vol. 10, issue 1, pp. 62, doi:
https://doi.org/10.3390/bioengineering10010062, 2023.
Martins E. G., Diogo G. S., Pires R. A., Reis R. L., and Silva T. H.,
"3D Biocomposites Comprising Marine Collagen and Silica-Based Materials Inspired on the Composition of Marine Sponge Skeletons Envisaging Bone Tissue Regeneration",
Marine Drugs, vol. 20, issue 11, pp. 718, doi:
10.3390/md20110718, 2022.
Reys L. L., Silva S. S., Soares da Costa D., Reis R. L., and Silva T. H.,
"Fucoidan-based hydrogels particles as versatile carriers for diabetes treatment strategies",
Journal of Biomaterials Science, Polymer Edition , vol. 33, issue 15, pp. 1339-1954, doi:
https://doi.org/10.1080/09205063.2022.2088533, 2022.
Carvalho D. N., Gonçalves C., Oliveira J. M., Williams D. S., Mearns Spragg A., Reis R. L., and Silva T. H.,
"A Design of Experiments (DoE) Approach to Optimize Cryogel Manufacturing for Tissue Engineering Applications",
Polymers, vol. 14, pp. 2026-2046, doi:
10.3390/polym14102026, 2022.
Carvalho D. N., Williams D. S., Sotelo C. G., Pérez-Marin R. I., Mearns Spragg A., Reis R. L., and Silva T. H.,
"Marine origin biomaterials using a compressive and absorption methodology as cell-laden hydrogel envisaging cartilage tissue engineering",
Biomaterials Advances, doi:
10.1016/j.bioadv.2022.212843, 2022.
Alves A. L., Fraguas F. J., Carvalho A. C., Valcarcel J., Pérez-Martín R. I., Reis R. L., Vázquez J. A., and Silva T. H.,
"Characterization of codfish gelatin: A comparative study of fresh and salted skins and different extraction methods",
Food Hydrocolloids, vol. 124, issue PA, doi:
10.1016/J.FOODHYD.2021.107238, 2022.
Alves A. L., Costa-Gouveia J., Vieira de Castro J., Sotelo C. G., Vázquez J. A., Pérez Martín R. I., Torrado E., Neves N. M., Reis R. L., Castro A. G., and Silva T. H.,
"Study of the immunologic response of marine-derived collagen and gelatin extracts for tissue engineering applications",
Acta Biomaterialia, vol. 141, pp. 123-131, doi:
10.1016/j.actbio.2022.01.009, 2022.
Carvalho D. N., Gonçalves C., Oliveira J. M., Willliams D., Mearns Spragg A., Reis R. L., and Silva T. H.,
"Innovative methodology for marine collagen-chitosan-fucoidan hydrogels production, tailoring rheological properties towards biomedical application",
Green Chemistry, pp. 1-14, doi:
10.1039/D1GC02223G, 2021.
Diogo G. S., Carneiro F., Freitas-Ribeiro S., Sotelo C. G., Pérez Martín R. I., Pirraco R. P., Reis R. L., and Silva T. H.,
"Prionace glauca skin collagen bioengineered constructs as a promising approach to trigger cartilage regeneration",
Materials Science and Engineering:C, doi:
10.1016/j.msec.2020.111587, 2021.
Carvalho D. N., López-Cebral R., Sousa R. O., Alves A. L., Silva S. S., Oliveira J. M., Reys L. L., Reis R. L., and Silva T. H.,
"Marine collagen-chitosan-fucoidan cryogels as cell-laden biocomposites envisaging tissue engineering",
Biomedical Materials, vol. 15, issue 5, pp. 055030, doi:
10.1088/1748-605X/ab9f04, 2020.
Diogo G. S., Marques C. F., Sotelo C. G., Pérez-Marin R. I., Pirraco R. P., Reis R. L., and Silva T. H.,
"Cell-Laden Biomimetially Mineralized Shark-Skin-Collagen-Based 3D Printed Hydrogels for the Engineering of Hard Tissues ",
ACS Biomaterials Science & Engineering, vol. 6, issue 6, pp. 3664–3672, doi:
10.1021/acsbiomaterials.0c00436, 2020.
Sousa R. O., Alves A. L., Carvalho D. N., Martins E., Oliveira C., Silva T. H., and Reis R. L.,
"Acid and enzymatic extraction of collagen from Atlantic cod (Gadus Morhua) swim bladders envisaging health-related applications",
Journal of Biomaterials Science, Polymer Edition, doi:
10.1080/09205063.2019.1669313, 2019.
Carvalho A. M., Marques A. P., Silva T. H., and Reis R. L.,
"Evaluation of the Potential of Collagen from Codfish Skin as a Biomaterial for Biomedical Applications",
Marine Drugs, vol. 16, issue 12, pp. 495-509, doi:
10.3390/md16120495, 2018.
Diogo G. S., Senra E. L., Pirraco R. P., Canadas R. F., Fernandes E. M., Serra J., Pérez-Martín R. I., Sotelo C. G., Marques A. P., González P., Moreira-Silva J., Silva T. H., and Reis R. L.,
"Marine collagen/apatite composite scaffolds envisaging hard tissue applications",
Marine Drugs, vol. 16, issue 8, pp. 269, doi:
10.3390/md16080269, 2018.
Fassini D., Duarte A. R. C., Reis R. L., and Silva T. H.,
"Bioinspiring Chondrosia reniformis (Nardo, 1847) Collagen-Based Hydrogel: A New Extraction Method to Obtain a Sticky and Self-Healing Collagenous Material",
Marine Drugs, vol. 15, issue 12, pp. 380-397, doi:
10.3390/md15120380, 2017.
Alves A. L., Marques A. L., Martins E., Silva T. H., and Reis R. L.,
"Cosmetic Potential of Marine Fish Skin Collagen",
Cosmetics, 39, vol. 4, issue 4, doi:
10.3390/cosmetics4040039, 2017.
Reys L. L., Silva S. S., Pirraco R. P., Marques A. P., Mano J. F., Silva T. H., and Reis R. L.,
"Influence of freezing temperature and deacetylation degree on the performance of freeze-dried chitosan scaffolds towards cartilage tissue engineering",
European Polymer Journal, vol. 95, issue C, pp. 232-240, doi:
10.1016/j.eurpolymj.2017.08.017, 2017.
Coelho R. C. G., Marques A. L. P., Oliveira S. M., Diogo G. S., Pirraco R. P., Moreira-Silva J., Xavier J. C., Reis R. L., Silva T. H., and Mano J. F.,
"Extraction and characterization of collagen from Antarctic and Sub-Antarctic squid and its potential application in hybrid scaffolds for tissue engineering",
Materials Science & Engineering C-materials For Biological Applications, vol. 78, doi:
10.1016/j.msec.2017.04.122, 2017.
Raftery R. M., Woods B., Marques A. L. P., Moreira-Silva J., Silva T. H., Cryan S. - A., Reis R. L., and O'Brien F. J.,
"Multifunctional Biomaterials from the Sea: Assessing the effects of Chitosan incorporation into Collagen Scaffolds on Mechanical and Biological Functionality",
Acta Biomaterialia, vol. 43, pp. 160-169, doi:
10.1016/j.actbio.2016.07.009, 2016.
Reys L. L., Silva S. S., Soares da Costa D., Oliveira N. M., Mano J. F., Reis R. L., and Silva T. H.,
"Fucoidan hydrogels photo-cross-linked with visible radiation as matrices for cell culture",
ACS Biomaterials Science & Engineering, vol. 2, issue 7, pp. 1151–1161, doi:
10.1021/acsbiomaterials.6b00180, 2016.
Review Paper (6)
Fernandes A. S., Oliveira C., Reis R. L., Martins A., and Silva T. H.,
"Marine-Inspired Drugs and Biomaterials in the Perspective of Pancreatic Cancer Therapies",
Marine Drugs, vol. 20, issue 11, pp. 689, doi:
10.3390/md20110689, 2022.
Romano G., Mariana A., Coelho A. V., Cutignano A., Gonçalves L. G., Hansen E., Khnykin D., Mass T., Ramšak A., Rocha M. S., Silva T. H., Sugni M., Ballarin L., and Geneviere A. - M.,
"Biomaterials and Bioactive Natural Products from Marine Invertebrates: From Basic Research to Innovative Applications",
Marine Drugs, vol. 20, issue 4, pp. 219, doi:
10.3390/md20040219, 2022.
Silva T. H., Moreira-Silva J., Marques A. L. P., Domingues A., Bayon Y., and Reis R. L.,
"Marine Origin Collagens and Its Potential Applications",
Marine Drugs, vol. 12, issue 12, pp. 5881-5901, doi:
10.3390/md12125881, 2014.
Silva T. H., Alves A., Popa E. G., Reys L. L., Gomes M. E., Sousa R. A., Silva S. S., Mano J. F., and Reis R. L.,
"Marine Algae Sulfated Polysaccharides for Tissue Engineering and Drug Delivery Approaches",
BioMatter, vol. 2, issue 4, pp. 278-289, doi:
doi.org/10.4161/biom.22947, 2012.
Book Chapter (5)
Reys L. L., Silva S. S., Oliveira C., López-Cebral R., Neves N. M., Martins A., Oliveira J. M., Silva T. H., and Reis R. L.,
"Marine-origin Polysaccharides for Tissue Engineering and Regenrative Medicine, Chitosan and Fucoidan as illustrative examples"",
Encyclopedia of Marine Biotechnology,
Eds. Kim S. - K.,
Wiley, vol. IV, pp. 2619-2650, doi:
https://doi.org/10.1002/9781119143802.ch118, 2020.
Martins E., Rocha M. S., Silva T. H., and Reis R. L.,
"Remarkable Body Architecture of Marine Sponges as Biomimetic Structure for Application in Tissue Engineering",
Marine-Derived Biomaterials for Tissue Engineering Applications,
Eds. Choi A. H., and Besim B. - N.,
Springer Series in Biomaterials Science and Engineering, Springer, Singapore, vol. 14, pp. 27-50, doi:
https://doi.org/10.1007/978-981-13-8855-2_2, 2019.
Moreira-Silva J., Diogo G. S., Marques A. L. P., Silva T. H., and Reis R. L.,
"Marine Collagen Isolation and Processing Envisaging Biomedical Applications",
Biomaterials from Nature for Advanced Devices and Therapies,
Eds. Neves N. M., and Reis R. L.,
Wiley, 1, pp. 16-36, 2016.
Invited Lecture (2)
Conference Abstract -ISI Web of Science Indexed (2)
Barros, A. A., Aroso I. M., Silva T. H., Mano J. F., Duarte A. R. C., and Reis R. L.,
"Bioactive ceramics for tissue engineering and regenerative medicine derived from marine sponges",
Tissue Engineering And Regenerative Medicine, Suppl 1, vol. 8, pp. 39-206, doi:
10.1002/term.1931, 2014.