Papers in Scientific Journals (11)
Reys L. L., Silva S. S., Costa D., Soares da Costa D., Rodrigues, L.C., Reis R. L., and Silva T. H.,
"Building Fucoidan/Agarose-Based Hydrogels as a Platform for the Development of Therapeutic Approaches against Diabetes",
Molecules, vol. 28, pp. 4523, doi:
https://doi.org/10.3390/ molecules28114523, 2023.
Reys L. L., Silva S. S., Soares da Costa D., Reis R. L., and Silva T. H.,
"Fucoidan-based hydrogels particles as versatile carriers for diabetes treatment strategies",
Journal of Biomaterials Science, Polymer Edition , vol. 33, issue 15, pp. 1339-1954, doi:
https://doi.org/10.1080/09205063.2022.2088533, 2022.
Reys L. L., Silva S. S., Oliveira C., Neves N. M., Martins A., Reis R. L., and Silva T. H.,
"Angiogenic potential of airbrushed fucoidan/polycaprolactone nanofibrous meshes",
International Journal Of Biological Macromolecules, vol. 183, pp. 695-706, doi:
10.1016/j.ijbiomac.2021.04.166, 2021.
Reys L. L., Vaithilingam V., Sthijns M. M. J. P. E., Soares E., Rademakers T., de Vries R., Mohammed S. M., de Bont D., Jetten M., Hermanns C., Filho O. P. S., Stell A., Mourad N. I., Gianello P., Lapointe V. L. S., Silva S. S., Reis R. L., Silva T. H., and van Apeldoorn A. A.,
"Fucoidan hydrogels significantly alleviate oxidative stress and enhance the endocrine function of encapsulated beta cells",
Advanced Functional Materials, vol. 31, pp. 2011205, doi:
10.1002/adfm.202011205, 2021.
Carvalho D. N., López-Cebral R., Sousa R. O., Alves A. L., Silva S. S., Oliveira J. M., Reys L. L., Reis R. L., and Silva T. H.,
"Marine collagen-chitosan-fucoidan cryogels as cell-laden biocomposites envisaging tissue engineering",
Biomedical Materials, vol. 15, issue 5, pp. 055030, doi:
10.1088/1748-605X/ab9f04, 2020.
López-Cebral R., Peng G., Reys L. L., Silva S. S., Oliveira J. M., Chen J., Silva T. H., and Reis R. L.,
"Dual delivery of hydrophilic and hydrophobic drugs from chitosan/ diatomaceous earth composite membranes",
Journal of Materials Science: Materials in Medicine, vol. 29, issue 3, pp. 21-33, doi:
10.1007/s10856-018-6025-9, 2018.
Reys L. L., Silva S. S., Pirraco R. P., Marques A. P., Mano J. F., Silva T. H., and Reis R. L.,
"Influence of freezing temperature and deacetylation degree on the performance of freeze-dried chitosan scaffolds towards cartilage tissue engineering",
European Polymer Journal, vol. 95, issue C, pp. 232-240, doi:
10.1016/j.eurpolymj.2017.08.017, 2017.
Reys L. L., Silva S. S., Soares da Costa D., Oliveira N. M., Mano J. F., Reis R. L., and Silva T. H.,
"Fucoidan hydrogels photo-cross-linked with visible radiation as matrices for cell culture",
ACS Biomaterials Science & Engineering, vol. 2, issue 7, pp. 1151–1161, doi:
10.1021/acsbiomaterials.6b00180, 2016.
Reys L. L., Silva S. S., Oliveira J. M., Caridade S. G., Mano J. F., Silva T. H., and Reis R. L.,
"Revealing the potential of squid chitosan-based structures for biomedical applications",
Biomedical Materials, vol. 8, issue 4, doi:
doi:10.1088/1748-6041/8/4/045002, 2013.
Silva S. S., Santos T. C., Cerqueira M. T., Marques A. P., Reys L. L., Silva T. H., Caridade S. G., Mano J. F., and Reis R. L.,
"The use of ionic liquids in the processing of chitosan/silk hydrogels for biomedical applications",
Green Chemistry , vol. 14, pp. 1463-1470, doi:
10.1039/C2GC16535J, 2012.
Reys L. L., Silva S. S., Oliveira J. M., Frias A. M., Mano J. F., Silva T. H., and Reis R. L.,
"Valorization of chitosan from squid pens and further use on the development of scaffolds for biomedicalapplications",
The International Journal of Artificial Organs, vol. 34, issue 8, pp. 704, 2012.
Review Paper (1)
Silva T. H., Alves A., Popa E. G., Reys L. L., Gomes M. E., Sousa R. A., Silva S. S., Mano J. F., and Reis R. L.,
"Marine Algae Sulfated Polysaccharides for Tissue Engineering and Drug Delivery Approaches",
BioMatter, vol. 2, issue 4, pp. 278-289, doi:
doi.org/10.4161/biom.22947, 2012.
Book Chapter (3)
Inácio A. R., Carvalho A. C., Oliveira C., Reys L. L., Silva S. S., Neves N. M., Martins A., Reis R. L., and Silva T. H.,
"Sulfated Seaweed Polysaccharides",
Polysaccharides of Microbial Origin,
Eds. Oliveira J. M., Radhouani H., and Reis R. L.,
Springer, Cham, doi:
doi.org/10.1007/978-3-030-35734-4_17-1, 2021.
Reys L. L., Silva S. S., Oliveira C., López-Cebral R., Neves N. M., Martins A., Oliveira J. M., Silva T. H., and Reis R. L.,
"Marine-origin Polysaccharides for Tissue Engineering and Regenrative Medicine, Chitosan and Fucoidan as illustrative examples"",
Encyclopedia of Marine Biotechnology,
Eds. Kim S. - K.,
Wiley, vol. IV, pp. 2619-2650, doi:
https://doi.org/10.1002/9781119143802.ch118, 2020.
Reys L. L., Oliveira C., Oliveira J. M., López-Cebral R., Silva S. S., Silva T. H., and Reis R. L.,
"Polissacarídeos de origem marinha para aplicação em estratégias de engenharia de tecidos",
Valorização dos Recursos Marinhos: Biomateriais em Regeneração de Tecidos e Libertação de Fármacos,
Eds. Carmen G. S., Pilar S. P., Julio M. L., José V. A., Ricardo P. M. I., Tiago S. H., and Reis R. L.,
IIM-CSIC, Vigo, Espanha, pp. 107-145, 2015.
Invited Review Paper (1)
Silva T. H., Alves A., Ferreira B. M., Oliveira J. M., Reys L. L., Ferreira R. F., Sousa R. A., Silva S. S., Mano J. F., and Reis R. L.,
"Materials of marine origin: a review on polymers and ceramics of biomedical interest",
International Materials Reviews, vol. 57, issue 5, pp. 276-306, doi:
doi.org/10.1179/1743280412Y.0000000002, 2012.
Conference Abstract -ISI Web of Science Indexed (6)
Reys L. L., Silva S. S., Soares da Costa D., Oliveira N. M., Mano J. F., Reis R. L., and Silva T. H.,
"Evaluation of the potential of fucoidan-based microparticles for diabetes treatment",
European Cells & Materials, 1, vol. 1, issue 1, pp. P349, 2016.
Silva T. H., Oliveira C., Reys L. L., Soares da Costa D., Novoa-Carballal R., Oliveira N. M., Ferreira A. S., Nunes C., Silva S. S., Martins A., Coimbra M. A., Mano J. F., Neves N. M., and Reis R. L.,
"Biomedical potential of fucoidan, a seaweed sulfated polysaccharide: from a anticancer agent to a building block of cell encapsulating systems for regenerative medicine",
Front. Bioeng. Biotechnol, pp. 221, doi:
10.3389/conf.FBIOE.2016.01.00221, 2016.
Reys L. L., Silva S. S., Soares da Costa D., Oliveira N. M., Mano J. F., Silva T. H., and Reis R. L.,
"Fucoidan-based Particles for Diabetes Mellitus Treatment.",
Tissue Engineering Parte A, vol. 21, issue S1, pp. A204, doi:
10.1089/ten.tea.2015.5000.abstracts, 2015.
Reys L. L., Silva S. S., Pirraco R. P., Boutinguiza M., Comesana M., Lusquinos F., Pou J., Mano J. F., Silva T. H., and Reis R. L.,
"Biomedical exploitation of squid chitosan using particle aggregation derived composite scaffolds",
Journal of Tissue Engineering and Regenerative Medicine, Supp1, vol. 7, pp. 19, doi:
10.1002/term.1822, 2013.
Reys L. L., Silva S. S., Boutinguiza S. S., Comesana M., Lusquinos R., Pou J., Mano J. F., Silva T. H., and Reis R. L.,
"Development of marine-based nanocomposite scaffolds for biomedical applications",
3rd Termis World Congress 2012, 2012.
Comunications - Poster (12)
Silva T. H., Oliveira C., Reys L. L., Soares da Costa D., Novoa-Carballal R., Oliveira N. M., Ferreira A. S., Nunes C., Silva S. S., Martins A., Coimbra M. A., Mano J. F., Neves N. M., and Reis R. L.,
"BIOMEDICAL POTENTIAL OF FUCOIDAN, A SEAWEED SULFATED POLYSACCHARIDE: FROM A ANTICANCER AGENT TO A BUILDING BLOCK OF CELL ENCAPSULATING SYSTEMS FOR REGENERATIVE MEDICINE",
10th World Biomaterials Congress, 2016.
Silva T. H., Barros, A. A., Marques A. L. P., Duarte A. R. C., Diogo G. S., Moreira-Silva J., Reys L. L., Silva S. S., and Reis R. L.,
"The Oceans as a Source and as an Inspiration for Biomaterials Development: Some key examples",
26th Annual Conference – European Society for Biomaterials, 2014.
Reys L. L., Silva S. S., Oliveira J. M., Caridade S. G., Mano J. F., Silva T. H., and Reis R. L.,
"Unraveling the potential of chitosan derived from squid pens for development of structures for tissue
engineering",
1st SPECIAL Open day - Marine Biotechnology,, 2011.
Comunication - Oral (2)
Silva T. H., Alves A., Ferreira B. M., Moreira-Silva J., Reys L. L., Ferreira R. F., Sousa R. A., Silva S. S., Mano J. F., and Reis R. L.,
"Valorization of marine resources: unraveling high-potential materials",
2nd IBB (Institute for Biotechnology and Bioengineering) Scientific Meeting, 2010.