Research Projects
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Coordination of European Commission (EC) Funded projects
EXPERTISSUES
Title Novel Therapeutic Strategies for Tissue Engineering of Bone and Cartilage Using Second Generation Biomimetic Scaffolds Type: Network of Excelence (NoE) Contract Number: NMP3-CT-2004-500283-2 Funding Agency EU-EC Funding Program FP6 Budget Total = €7300000,00 M 3B's = €1796861,66 M Coordination Institution: 3B’s Research Group – University of Minho (Portugal) Principal Coordinator: Rui L. Reis Number of Partners: 20 Duration Start Date:2004-10-01 End Date:2009-09-30 URL: http://www.expertissues.eu publications list FoReCaST
Title Forefront Research in 3D Disease Cancer Models as in vitro Screening Technologies Type: Horizon 2020 Contract Number: 668983-FoReCaST Reference: n.a. Funding Agency EU-EC Funding Program Horizon 2020 Budget Total = €2499755 M 3B's = €2499755 M Coordination Institution: UMinho Principal Investigator: Rui L. Reis 3B's Coordinator: Rui L. Reis Number of Partners: 7 Duration Start Date:2015-07-01 End Date:2021-12-31 URL: http://forecast.3bs.pt/ publications list 
ECaBox
Title ECaBox "Eyes in a Care Box": Regenerating human retina from resuscitated cadaveric eyes Type: Horizon 2020 Contract Number: 964342 Reference: 964342 Funding Agency EU-EC Funding Program Horizon 2020 Budget Total = €550 M 3B's = €550 M Coordination Institution: Principal Coordinator: Number of Partners: Duration Start Date:2021-09-01 End Date:2029-08-31 publications list BioPrint4All
Title A 3D-bioprinting platform with exchangeable tailor-made print heads to engineer tissue surrogates Type: ERC Contract Number: 899953 Reference: 899953 Funding Agency EU-EC Funding Program ERC Budget Total = €150000 M 3B's = €150000 M Coordination Institution: Principal Coordinator: Number of Partners: Duration Start Date:2020-09-01 End Date:2022-02-28 URL: https://cordis.europa.eu/project/id/899953 
CapBed
Title Engineered Capillary Beds for Successful Prevascularization of Tissue Engineering Constructs Type: ERC Contract Number: 805411 Reference: CapBed Funding Agency EU-EC Funding Program ERC Budget Total = €1.5 M 3B's = €1.5 M Coordination Institution: Principal Coordinator: Number of Partners: Duration Start Date:2018-11-01 End Date:2025-04-30 URL: https://cordis.europa.eu/project/id/805411 publications list 
Achilles
Title OVERCOMING SPECIFIC WEAKENESSES IN TENDON BIOLOGY TO DESGIN ADVANCED REGENERATIVE THERAPI Type: Horizon 2020 Contract Number: 810850 Reference: 810850 Funding Agency EU-EC Funding Program Horizon 2020 Budget Total = €1000000 M 3B's = €500000 M Coordination Institution: Principal Coordinator: Number of Partners: Duration Start Date:2018-10-01 End Date:2022-06-30 URL: https://achilles.i3bs.eu/ publications list 
ECM_INK
Title Cells-self Extracellular Matrices-based Bioinks to create accurate 3D diseased skin tissue models Type: ERC Contract Number: 726061 Reference: - Funding Agency EU-EC Funding Program ERC Budget Total = €1998939 M 3B's = €1998939 M Coordination Institution: University of Minho Principal Investigator: Alexandra Marques 3B's Coordinator: Alexandra Marques Number of Partners: 1 Duration Start Date:2017-05-01 End Date:2023-07-31 URL: https://cordis.europa.eu/project/id/726061 publications list 
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Participation in European Commission (EC) Funded projects
NanoTech4ALS
Title MRI-guided, intrathecal delivery of nanogel-embedded glial progenitors for treatment of amyotrophic lateral sclerosis Type: FP7 Programme Contract Number: EuronanomedII-2015 Reference: N/A Funding Agency EU-EC Funding Program ERA-Net Budget Total = €891972 M 3B's = €124896 M Coordination Institution: University of Warmia and Mazury in Olsztyn Principal Investigator: Piotr Walczak 3B's Coordinator: Joana Silva-Correia Number of Partners: 4 Duration Start Date:2016-09-01 End Date:2021-02-28 publications list 
SponGES
Title Deep-sea Sponge Grounds Ecosystems of the North Atlantic Type: Horizon 2020 Contract Number: 679849 Reference: SEP 679849-2 Funding Agency EU-EC Funding Program Horizon 2020 Budget Total = €9.994 M 3B's = €0.375 M Coordination Institution: University of Bergen, Norway Principal Investigator: Hans Tore Rapp 3B's Coordinator: Rui L. Reis Number of Partners: 15 Duration Start Date:2016-03-01 End Date:2020-12-31 URL: http://www.deepseasponges.org/ publications list 
BLUES
Title Bioprocesses for metaboLite prodUction from marinEinvertebrate cell lineS Type: Horizon Europe Contract Number: 101134820 — BLUES Reference: 101134820 — BLUES Funding Agency EU-EC Funding Program Horizon Europe Budget Total = €4 M 3B's = €0.475 M Coordination Institution: Principal Coordinator: Number of Partners: Duration Start Date:2024-01-01 End Date:2027-12-31 MARINNONET
Title Transnational R&D&I cooperation network to foster the competitiveness and sustainability of the Blue Biotech sector in the Atlantic Area territory Type: Atlantic Area Transnational Programme Contract Number: EAPA_0017/2022 Reference: EAPA_0017/2022 Funding Agency ADC - Agência para o Desenvolvimento e Coesão Funding Program Atlantic Area Transnational Programme Budget Total = €2.32 M 3B's = €0.26 M Coordination Institution: Principal Coordinator: Number of Partners: Duration Start Date:2023-07-01 End Date:2026-06-30 IBEROS+
Title Instituto de Biofabricación em Red para el Envejecimiento Saludable (IBEROS+) Type: POCTEP Contract Number: 0072_IBEROS_MAIS_1_E Reference: 0072_IBEROS_MAIS_1_E Funding Agency CCDR-N Funding Program POCTEP Budget Total = €2.175 M 3B's = €0.105 M Coordination Institution: Principal Coordinator: Number of Partners: Duration Start Date:2023-07-01 End Date:2026-06-30 ONCOSCREEN
Title A European “shield” against colorectal cancer based on novel, more precise and affordable risk-based screening methods and viable policy pathways Type: R&D Projects Contract Number: 101097036 Reference: 101097036 Funding Agency EU-EC Funding Program Horizon Europe Budget Total = €12772701.25 M 3B's = €329975 M Coordination Institution: Principal Coordinator: Number of Partners: Duration Start Date:2022-09-09 End Date:2026-09-08 publications list APTADEGRAD
Title A novel, first-in-its-kind, aptamer-based LYTACs to address the unmet clinical need of diabetic wounds Type: Horizon 2020 Contract Number: 10109963 Reference: 101099063 Funding Agency EU-EC Funding Program Horizon Europe Budget Total = €2.3 M 3B's = €0.6 M Coordination Institution: Principal Coordinator: Number of Partners: Duration Start Date:2022-12-01 End Date:2027-11-30 publications list MEPHOS
Title Shaping the Mechano-Pharmacological properties of Microparticles and Extracellular Vesicles for the Treatment of Osteoarthritis Type: Marie Curie-RISE Contract Number: 872648-MEPHOS Reference: 872648-MEPHOS Funding Agency EU-EC Funding Program Marie Curie-RISE Budget Total = €864800 M 3B's = €225400 M Coordination Institution: Principal Coordinator: Number of Partners: Duration Start Date:2020-04-01 End Date:2028-03-31 publications list SHIFT
Title Shaping Innovative Designs for Sustainable Tissue Engineering Products Type: Horizon 2020 Contract Number: Grant agreement no. 101008041 Reference: Proposal number: 101008041 Funding Agency EU-EC Funding Program Marie Curie-RISE Budget Total = €91 M 3B's = €16.1 M Coordination Institution: Principal Coordinator: Number of Partners: Duration Start Date:2021-09-01 End Date:2025-08-31 publications list BAMOS
Title Biomaterials and Additive Manufacturing: Osteochondral Scaffold innovation applied to osteoarthritis Type: Marie Curie Actions (MCA) - People Contract Number: 20912 Reference: H2020-MSCA-RISE-2016-734156 Funding Agency EU-EC Funding Program Horizon 2020 Budget Total = €639000 M 3B's = €166500 M Coordination Institution: Universidad de Las Palmas de Gran Canaria (ULPGC) Principal Investigator: Mario Verona 3B's Coordinator: Rui Reis Number of Partners: 7 Duration Start Date:2017-01-01 End Date:2021-07-31 URL: http://www.risebamos.eu/index.php publications list 
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Industrial Funded Projects
Algavalor
Title MicroAlgas: produção integrada e valorização da biomassa e das suas diversas aplicações Type: Co-Promotion Projects Contract Number: NA Reference: NA Funding Agency FEDER Funding Program FEDER Budget Total = €12 M 3B's = €0.5 M Coordination Institution: Principal Coordinator: Number of Partners: Duration Start Date:2019-01-01 End Date:2022-12-31 URL: https://labs.3bs.uminho.pt/files/projects/613-algavalor.pdf 
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FCT (Portuguese Foundation for Science and Technology) Funded Projects
I-CARE
Title Implantable 3D-bioprinted glycopeptide-based patch for Cardiac tissue Repair Type: R&D Projects Contract Number: RESTART Reference: 2023.00076.RESTART Funding Agency FCT Funding Program RESTART Budget Total = €50000 M 3B's = €50000 M Coordination Institution: Principal Coordinator: Number of Partners: Duration Start Date:2023-12-23 End Date:2025-06-22 SMART-SHUTTLE
Title Tackling Tumor Heterogeneity Using Biomaterial-Based Multifunctional Nanocarriers Against Cancer Type: R&D Projects Contract Number: CEECIND/02842/2017 Reference: CEECIND/02842/2017 Funding Agency FCT Funding Program Scientific Employment Stimulus (Individual) Budget Total = €1 M 3B's = €1 M Coordination Institution: Principal Coordinator: Number of Partners: Duration Start Date:2019-05-02 End Date:2025-05-01 COMET
Title Cancer Optical fibers: pre-Metastatic Engineered Tissues Type: FCT R&D Project Contract Number: 2022.05737.PTDC Reference: 2022.05737.PTDC Funding Agency FCT Funding Program PTDC Budget Total = €24945995 M 3B's = €24945995 M Coordination Institution: Principal Coordinator: Number of Partners: Duration Start Date:2023-03-01 End Date:2026-02-28 publications list Wi-Pi
Title Wireless platform of abiotic nanoactuators to probe PIEZO receptors mechanobiology Type: FCT R&D Project Contract Number: 2022.05526.PTDC Reference: 2022.05526.PTDC Funding Agency FCT Funding Program PTDC Budget Total = €249360.20 M 3B's = €249360.20 M Coordination Institution: Principal Coordinator: Number of Partners: Duration Start Date:2023-03-01 End Date:2026-02-28 publications list 
RECOVER
Title Reversing cancer cachexia: understanding the role of micro/nano-vesicles in disease genesis and progression for better treatment response Type: FCT R&D Project Contract Number: 2022.02260.PTDC Reference: 2022.02260.PTDC Funding Agency FCT Funding Program PTDC Budget Total = €249471.71 M 3B's = €249471.71 M Coordination Institution: Principal Coordinator: Number of Partners: Duration Start Date:2023-03-01 End Date:2029-02-28 publications list 
3D printed Li-doped brushite cement/silk fibroin nanocomposites for bone tissue engineering
Title 3D printed Li-doped brushite cement/silk fibroin nanocomposites for bone tissue engineering Type: N/D Contract Number: xx Reference: 2021.09746.CBM Funding Agency FCT Funding Program FEDER/COMPETE Budget Total = €4000 M 3B's = €4000 M Coordination Institution: Principal Coordinator: Number of Partners: Duration Start Date:2023-01-02 End Date:2025-01-01 RePark
Title Refining the efficacy of systemic administration of bioactive molecules for Parkinson Type: ERA-Net Contract Number: M-ERA-NET3/0007/2021 Reference: M-ERA-NET3/0007/2021 Funding Agency FCT Funding Program ERA-Net Budget Total = €650506.00 M 3B's = €249703.00 M Coordination Institution: Principal Coordinator: Number of Partners: Duration Start Date:2022-09-30 End Date:2028-09-29 SpyPatch
Title Modular spider silk and elastin recombinamers for soft tissue repair patches Type: FCT R&D Project Contract Number: PTDC/BTM-MAT/2844/2021 Reference: PTDC/BTM-MAT/2844/2021 Funding Agency FCT Funding Program PTDC Budget Total = €248453.71 M 3B's = €248453.71 M Coordination Institution: Principal Coordinator: Number of Partners: Duration Start Date:2022-01-01 End Date:2024-12-31 UIDP/50026/2020
Title ICVS/3B’s - Laboratório Associado, Instituto de Ciências da Vida e da Saúde / Grupo de Investigação em Biomateriais, Biodegradaveis e Biomiméticos Type: FCT R&D Project Contract Number: UIDP/50026/2020 Reference: UIDP/50026/2020 Funding Agency FCT Funding Program Compete2020 Budget Total = €970000 M 3B's = €485000 M Coordination Institution: Principal Coordinator: Number of Partners: Duration Start Date:2020-01-01 End Date:2024-12-31 publications list UIDB/50026/2020
Title ICVS/3B’s - Laboratório Associado, Instituto de Ciências da Vida e da Saúde / Grupo de Investigação em Biomateriais, Biodegradaveis e Biomiméticos Type: FCT R&D Project Contract Number: UIDB/50026/2020 Reference: UIDB/50026/2020 Funding Agency FCT Funding Program Compete2020 Budget Total = €2333025.00 M 3B's = €1166512.50 M Coordination Institution: Principal Coordinator: Number of Partners: Duration Start Date:2020-01-01 End Date:2024-12-31 MyµMAT
Title Enabling point-of-care (POC) diagnostics of acute MYocardial infarction (AMI) using 3D micro-engineered bioMATterials in microfluidic devices. Type: FCT R&D Project Contract Number: PTDC/CTM-CTM/2846/2020 Reference: PTDC/CTM-CTM/2846/2020 Funding Agency FCT Funding Program PTDC Budget Total = €249235.49 M 3B's = €249235.49 M Coordination Institution: Principal Coordinator: Number of Partners: Duration Start Date:2021-12-03 End Date:2024-12-02 publications list 
OncoNeoTreat
Title Inorganic-Templated and Polymeric Layer-by-Layer Microcapsules with Multimodal Drug Loading to Treat Breast Cancer Type: FCT R&D Project Contract Number: PTDC/CTM-REF/0022/2020 Reference: PTDC/CTM-REF/0022/2020 Funding Agency FCT Funding Program PTDC Budget Total = €248610.48 M 3B's = €248610.48 M Coordination Institution: Principal Coordinator: Number of Partners: Duration Start Date:2021-02-01 End Date:2024-07-31 publications list CARTI-LIKE
Title RECONSTRUCTION OF CARTILAGE NANOSTRUCTURE BY BRUSH LIKE COPOLYMERS THAT MIMIC PROTEOGLYCANS Type: FCT R&D Project Contract Number: PTDC/QUI-POL/28117 (POCI-01-0145-FEDER-028117) Reference: C491773512-00084360 Funding Agency FCT Funding Program POCI Budget Total = €239183.13 M 3B's = €239183.13 M Coordination Institution: Principal Coordinator: Number of Partners: Duration Start Date:2018-07-01 End Date:2022-06-30 publications list 
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Previously EC Funded Projects
ValorMar
Title Valorização Integral dos recursos marinhos: potencial, inovação tecnológica e novas aplicações Type: Co-Promotion Projects Contract Number: POCI-01-0247-FEDER-024517 Reference: POCI-01-0247-FEDER-024517 Funding Agency ANI (Agência Nacional de Inovação) Funding Program European Regional Development Fund (ERDF) Budget Total = €8.043 M 3B's = €0.215 M Coordination Institution: Principal Coordinator: Number of Partners: Duration Start Date:2017-10-01 End Date:2021-07-31 URL: http://valormar.pt/ publications list -
R&D Grants
2023.07148.CEECIND
Title Spy2Function: Bioengineering spider silk-based responsive living patches for abdominal tissue repair Type: R&D Projects Contract Number: 2023.07148.CEECIND Reference: 2023.07148.CEECIND Funding Agency FCT Funding Program Scientific Employment Stimulus (Individual) Budget Total = €1 M 3B's = €1 M Coordination Institution: Principal Coordinator: Number of Partners: Duration Start Date:2024-11-01 End Date:2030-10-31 -
Other
SmarNanoTen
Title Smart nanocarrier for targeting NFkB pathway in tendon inflammation Type: Pilot and Feasibility (PNF) single-project Contract Number: 22-074 Reference: ON Pilot Grant Ankle 2022 Funding Agency ON - Orthoregeneration Network Funding Program ON Pilot Grants Budget Total = €26.147 M 3B's = €26.147 M Coordination Institution: Principal Coordinator: Number of Partners: Duration Start Date:2022-10-01 End Date:2024-09-30 PactoBioeconomiaAzul
Title Pacto para a Bioeconomia Azul - Agenda Mobilizadora para a Inovação Empresarial Type: N/D Contract Number: C645192610-00000060 Reference: C645192610-00000060 Funding Agency IAPMEI Funding Program Plano de Recuperação e Resiliência Budget Total = €94 M 3B's = €1 M Coordination Institution: Principal Coordinator: Number of Partners: Duration Start Date:2022-01-01 End Date:2025-12-31 
2iqbioneuro
Title Impulso de una red de I+i en química biológica para diagnóstico y tratamiento de enfermedades neurológicas Type: POCTEP Contract Number: 0624_2IQBIONEURO_6_E Reference: 0624_2IQBIONEURO_6_E (POCTEP Interreg) Funding Agency FEDER Funding Program POCTEP Budget Total = €1560185.5 M 3B's = €74570.15 M Coordination Institution: Principal Coordinator: Number of Partners: Duration Start Date:2019-05-23 End Date:2022-12-22 URL: https://2iqbioneuro.wordpress.com/ publications list BlueHuman
Title BLUE biotechnology as a road for innovation on HUMAN’s health aiming smart growth in Atlantic Area Type: Atlantic Area Transnational Programme Contract Number: EAPA_151/2016 Reference: EAPA_151/2016 Funding Agency FEDER Funding Program Atlantic Area Transnational Programme Budget Total = €2.524 M 3B's = €0.4 M Coordination Institution: Principal Coordinator: Number of Partners: Duration Start Date:2018-01-01 End Date:2021-12-31 URL: http://bluehuman.cetmar.org/ publications list Dressing4scars
Title New 4D printing dressing to treat skin scars Type: ERA-Net Contract Number: -- Reference: ERA-NET / CSA / JPI/M-ERANET Funding Agency FCT Funding Program ERA-Net Budget Total = €530081 M 3B's = €199992 M Coordination Institution: Principal Coordinator: Number of Partners: Duration Start Date:2017-09-01 End Date:2020-11-30 URL: http://dressing4scars.3bs.pt publications list KrEaTive Habitat
Title Transferência e divulgação da pesquisa aplicada relacionada com as Tecnologias Facilitadoras Essenciais (KETs) para a indústria de materiais do Habitat para promover novas aplicações dentro das indústrias criativas no espaço Sudoe Type: INTERREG V SUDOE Contract Number: SOE1/P1/E0307 Reference: SOE1/P1/E0307 Funding Agency FEDER Funding Program INTERREG V SUDOE Budget Total = €1191227,77 M 3B's = €131962 M Coordination Institution: Fundación Centro Tecnológico de Componentes Principal Investigator: Antonio Segura Pérez 3B's Coordinator: Rui L. Reis Number of Partners: 7 Duration Start Date:2017-02-22 End Date:2020-02-21 URL: http://www.kreativehabitat.eu/ publications list -
Portugal2020
TERM RES Hub
Title TERM RES Hub - Infraestrutura Científica para a Engenharia de Tecidos e Medicina Regenerativa Type: N/D Contract Number: PINFRA/22190/2016 Reference: Norte-01-0145-FEDER-022190 Funding Agency CCDR-N Funding Program Norte2020 Budget Total = €1079997383 M 3B's = €1079997383 M Coordination Institution: Principal Coordinator: Number of Partners: Duration Start Date:2017-09-04 End Date:2021-09-03 publications list HydrUMetal
Title A metal-based biodegradable ureteral stent Type: Programa COMPETE Contract Number: 047112 Reference: NORTE-01-0247-FEDER-047112 Funding Agency ANI (Agência Nacional de Inovação) Funding Program Compete2020 Budget Total = €97688847 M 3B's = €23400800 M Coordination Institution: Principal Coordinator: Number of Partners: Duration Start Date:2020-07-01 End Date:2023-06-30 URL: https://labs.3bs.uminho.pt/public.php?file=0edc93e97d93e9302a41f6ba60639edf 
CVMar+i
Title Inovação industrial através de colaborações específicas entre empresas e centros de investigação no contexto de valorização biotecnológica marinha Type: POCTEP Contract Number: 0302_CVMAR_I_1_P Reference: 0302_CVMAR_I_1_P Funding Agency CCDR-N Funding Program POCTEP Budget Total = €2132000 M 3B's = €420000 M Coordination Institution: University of Minho Principal Investigator: Rui L. Reis 3B's Coordinator: Rui L. Reis Number of Partners: 19 Duration Start Date:2017-07-01 End Date:2020-12-31 URL: http://cvmari.cetmar.org/ publications list -
Norte2020
HEALTH UNORTE
Title HEALTH-UNORTE: Setting-up biobanks and regenerative medicine strategies to boost research in cardiovascular, musculoskeletal, neurological, oncological, immunological and infectious diseases Type: Projeto Estruturado Contract Number: NORTE-01-0145-FEDER-000039 Reference: NORTE-01-0145-FEDER-000039 Funding Agency CCDR-N Funding Program Norte2020 Budget Total = €3.5 M 3B's = €0.742 M Coordination Institution: Principal Coordinator: Number of Partners: Duration Start Date:2020-10-01 End Date:2023-09-30 publications list ATLANTIDA
Title Platform for the monitoring of the North Atlantic ocean and tools for the sustainable exploitation of the marine resources Type: Projeto Estruturado Contract Number: NORTE-01-0145-FEDER-000040 Reference: NORTE-01-0145-FEDER-000040 Funding Agency CCDR-N Funding Program Norte2020 Budget Total = €2.940 M 3B's = €0.286 M Coordination Institution: Principal Coordinator: Number of Partners: Duration Start Date:2020-10-01 End Date:2023-09-30 publications list FROnTHERA
Title Frontiers of technology for theranostics of cancer, metabolic and neurodegenerative diseases Type: Projeto Estruturado Contract Number: NORTE-01-0145-FEDER-000023 Reference: NORTE-01-0145-FEDER-000023 Funding Agency CCDR-N Funding Program FEDER Budget Total = €3469925.85 M 3B's = €1361732.49 M Coordination Institution: UMinho Principal Investigator: Nuno Neves 3B's Coordinator: Nuno Neves Number of Partners: 2 Duration Start Date:2016-04-01 End Date:2020-07-31 URL: http://www.3bs.uminho.pt/projects#projectid-486 publications list 
NORTE45_3Bs
Title Accelerating tissue engineering and personalized medicine discoveries by the integration of key enabling nanotechnologies, marine-derived biomaterials and stem cells Type: Projeto Estruturado Contract Number: NORTE-01-0145-FEDER-000021 Reference: NORTE-45-2015-02: candidatura 770 Funding Agency CCDR-N Funding Program Norte2020 Budget Total = €3471402.91 M 3B's = €3471402.91 M Coordination Institution: University of MInho Principal Investigator: Rui L. Reis 3B's Coordinator: Rui L. Reis Number of Partners: Duration Start Date:2016-04-01 End Date:2020-07-31 publications list 
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Awards, Nominations & Honorific Distinctions
VECTOR
Title Deteção Precoce da Recidiva do Cancro através de um Dispositivo Microfluídico da Biópsia Líquida de Vesículas Extracelulares e Cromatografia Type: Research & Development Awards Contract Number: N/A Reference: 5 ENJIO Funding Agency Liga Portuguesa Contra o Cancro - BioPortugal Funding Program Prémio “Liga Inovação” Budget Total = €0.007500 M 3B's = €0.007500 M Coordination Institution: Principal Coordinator: Number of Partners: Duration Start Date:2023-10-01 End Date:2025-09-30 
