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2012
Costa P. F.
,
Martins A.
,
Vaquette C.
,
Neves N. M.
,
Gomes M. E.
,
Hutmacher D. W.
,
Reis R. L.
, and
Melchels F. P. W.
,
"
Bioreactor composed of watertight chamber and internal matrix for the generation of cellularized medical implants
",
EP2800807 (A1) 2014-11-12
, 2012.
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Costa P. F.
,
Vaquette C.
,
Gomes M. E.
,
Reis R. L.
, and
Hutmacher D. W.
,
"
All-in-one rapid-prototyped bioreactor/implant for semi-automated generation of tailor-made critical size bone tissue substitutes
",
Journal of Tissue Engineering and Regenerative Medicine
, vol. 6, issue S1, pp. 331-331, doi:
10.1002/term.1586
, 2012.
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RepositoriUM
Duarte A. R. C.
,
Santo V. E.
,
Gomes M. E.
,
Mano J. F.
, and
Reis R. L.
,
"
Platelet lysates scaffolds prepared by supercritical fluid technology as autologous templates for cartilage regeneration
",
3rd TERMIS World Congress
, 2012.
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Duarte A. R. C.
,
Santo V. E.
,
Gomes M. E.
,
Mano J. F.
, and
Reis R. L.
,
"
Scaffolds prepared by supercritical fluid technology as autologous templates for osteochondral regeneration
",
Journal of Tissue Engineering and Regenerative Medicine
, S, vol. 6, issue 1, pp. 197, doi:
10.1002/term.1586
, 2012.
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Gonçalves A. I.
,
Rodrigues M. T.
,
Reis R. L.
, and
Gomes M. E.
,
"
Induction of tenogenic differentiation in human adipose stem cells by manipulating culture medium supplements
",
Journal of Tissue Engineering and Regenerative Medicine
, vol. 6, pp. 49-49, 2012.
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RepositoriUM
Costa P. F.
,
Vaquette C.
,
Gomes M. E.
,
Reis R. L.
, and
Hutmacher D. W.
,
"
All-in-one rapid-prototyped bioreactor/implant for semi-automated generation of tailor-made critical size bone tissue substitutes
",
TERMIS World Congress
, 2012.
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Requicha J. F.
,
Viegas C. A. A.
,
Albuquerque C. M.
,
Azevedo J. M.
,
Reis R. L.
, and
Gomes M. E.
,
"
Canine adipose stem cells: the influence of the anatomy and passaging on the stemness and osteogenic differentiation potential
",
Term Stem 2012
, 2012.
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Babo P. S.
,
Santo V. E.
,
Gomes M. E.
, and
Reis R. L.
,
"
Development of a bilayered system for periodontal regeneration using tissue engineering approaches
",
Journal of Tissue Engineering and Regenerative Medicine
, vol. 6, issue s2, pp. 8-39, 2012.
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RepositoriUM
Rodrigues A. I.
,
Gomes M. E.
,
Leonor I. B.
, and
Reis R. L.
,
"
Bioactive starch-based scaffolds and human adipose stem cells are a goodcombination for bone tissue engineering
",
Acta Biomaterialia
, vol. 8, issue 10, pp. 3765–3776, doi:
10.1016/j.actbio.2012.05.025
, 2012.
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RepositoriUM
Popa E. G.
,
Rodrigues M. T.
,
Coutinho D. F.
,
Neves N. M.
,
Gomes M. E.
, and
Reis R. L.
,
"
Cryopreservation of cell laden natural origin hydrogels for cartilage regeneration strategies
",
Society for Biomaterials, 2012 Fall Symposium "Grand Challenges in Biomaterials"
, vol. No. 207, 2012.
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RepositoriUM
Popa E. G.
,
Rodrigues M. T.
,
Coutinho D. F.
,
Neves N. M.
,
Gomes M. E.
, and
Reis R. L.
,
"
Cryopreservation of cell laden natural origin hydrogels for cartilage regeneration strategies
",
Society for Biomaterials, 2012 Fall Symposium "Grand Challenges in Biomaterials"
, 2012.
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Mota J.
,
Yu N.
,
Caridade S. G.
,
Luz G. M.
,
Gomes M. E.
,
Reis R. L.
,
Jansen J. A.
, and
Walboomers X. F.
,
"
Chitosan/bioactive glass nanoparticle composite membranes for periodontal regeneration
",
Acta Biomaterialia
, vol. 8, issue 11, pp. 4173-4180, doi:
10.1016/j.actbio.2012.06.040
, 2012.
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RepositoriUM
Silva S. S.
,
Popa E. G.
,
Gomes M. E.
,
Oliveira M. B.
,
Mano J. F.
, and
Reis R. L.
,
"
Designing silk fibroin-based matrices with ionic liquids for tissue engineering strategies using human adipose stem cells
",
Journal of Tissue Engineering and Regenerative Medicine
, vol. 6, issue Suppl 2, pp. 17, 2012.
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RepositoriUM
Custódio C. A.
,
Santo V. E.
,
Gomes M. E.
,
Reis R. L.
, and
Mano J. F.
,
"
Development of bioactive constructs through cell crosslinking for tissue regeneration
",
TERM STEM
, vol. 6, issue Suppl.2, pp. 14, doi:
10.1002/term.1608
, 2012.
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RepositoriUM
Requicha J. F.
,
Viegas C. A. A.
,
Albuquerque C. M.
,
Azevedo J. M.
,
Reis R. L.
, and
Gomes M. E.
,
"
Canine adipose stem cells: the influence of the anatomy and passaging on the stemness and osteogenic differentiation potential
",
Journal of Tissue Engineering and Regenerative Medicine
, vol. 6, issue s2, pp. 31, doi:
10.1002/term.1608
, 2012.
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Rodrigues M. T.
,
Gonçalves A. I.
,
Lee S. J.
,
Atala A.
,
Yoo J.
,
Reis R. L.
, and
Gomes M. E.
,
"
Tenogenic potential of human stem cells from the amniotic fluid and adipose tissue
",
Journal of Tissue Engineering and Regenerative Medicine
, vol. 6, pp. 30-30, 2012.
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RepositoriUM
Requicha J. F.
,
Leonor I. B.
,
Muñoz F.
,
Moura T.
,
Azevedo J. M.
,
Gomes M. E.
, and
Reis R. L.
,
"
In vitro and in vivo assessment of an innovative double layer scaffold for periodontal tissue engineering
",
II 3B’s-ICVS Associate Laboratory Meeting
, 2012.
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Mihaila S. M.
,
Gaharwar A. K.
,
Reis R. L.
,
Marques A. P.
,
Gomes M. E.
, and
Khademhosseini A.
,
"
Methacrylated kappa-Carrageenan as a Photocrosslinkable Biopolymer for Tissue Engineering Applications
",
Biomedical Engineering Society (BMES)
, 2012.
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Costa P. F.
,
Dias A. F.
,
Reis R. L.
, and
Gomes M. E.
,
"
Cryopreservation of Cell/Scaffold Tissue-Engineered Constructs
",
Tissue Engineering Part C: Methods
, vol. 18, issue 11, pp. 852-858, doi:
10.1089/ten.tec.2011.0649
, 2012.
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Santo V. E.
,
Sato K.
,
Ratanavaraporn J.
,
Gomes M. E.
,
Mano J. F.
,
Reis R. L.
, and
Tabata Y.
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"
Enhanced orthotopic bone regeneration promoted by intracellular delivery of dexamethasone
",
3rd TERMIS World Congress 2012
, 2012.
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Coutinho D. F.
,
Santo V. E.
,
Mano J. F.
,
Neves N. M.
,
Gomes M. E.
, and
Reis R. L.
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"
Gradients of plaletet lysates as guiding mechanism for angiogenesis
",
3rd TERMIS World Congress 2012
, 2012.
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Santo V. E.
,
Sato K.
,
Ratanavaraporn J.
,
Gomes M. E.
,
Mano J. F.
,
Reis R. L.
, and
Tabata Y.
,
"
Intracellular delivery of dexamethasone as key supplement for new orthotopic bone formation
",
Fall Symposium of International Society for Biomaterials
, 2012.
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Coutinho D. F.
,
Santo V. E.
,
Caridade S. G.
,
Mano J. F.
,
Neves N. M.
,
Gomes M. E.
, and
Reis R. L.
,
"
Multi-functional injectable hydrogels for improved human adipose stem cell behavior
",
TERM STEM 2012
, 2012.
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Santo V. E.
,
Mano J. F.
,
Gomes M. E.
, and
Reis R. L.
,
"
Nanoparticles as tunable carriers or controlled release of bioactive agents for stem cell engineering
",
Workshop Nano12 - Shaping the Future
, 2012.
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Santo V. E.
,
Duarte A. R. C.
,
Mano J. F.
,
Gomes M. E.
, and
Reis R. L.
,
"
Platelet Lysates Scaffolds prepared by supercritical fluid technology as autologous hydrogels for cartilage engineering
",
Fall Symposium of International Society for Biomaterials
, 2012.
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Duarte A. R. C.
,
Santo V. E.
,
Gomes M. E.
,
Mano J. F.
, and
Reis R. L.
,
"
Platelet Lysates scaffolds produced by supercritical fluid technology as autologous templates for cartilage regeneration
",
3rd TERMIS World Congress 2012
, 2012.
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Santo V. E.
,
Duarte A. R. C.
,
Mano J. F.
,
Gomes M. E.
, and
Reis R. L.
,
"
Platelet lysates scaffolds with tunable gradients of mineral nanoparticles guide osteogenic differentiation of human adipose derived stem cells
",
TERM STEM 2012
, 2012.
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Custódio C. A.
,
Santo V. E.
,
Gomes M. E.
,
Reis R. L.
, and
Mano J. F.
,
"
Development of bioactive constructs through cell crosslinking for tissue regeneration
",
Journal of Tissue Engineering and Regenerative Medicine
, vol. 6, issue Suppl.2, pp. 14-14, doi:
10.1002/term.1608
, 2012.
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RepositoriUM
Santo V. E.
,
Duarte A. R. C.
,
Popa E. G.
,
Gomes M. E.
,
Mano J. F.
, and
Reis R. L.
,
"
Enhancement of osteogenic differentiation of human adipose derived stem cells by the controlled release of platelet lysates from hybrid scaffolds produced by supercritical fluid foaming
",
Journal of Controlled Release
, vol. 162, issue 1, pp. 19-27, 2012.
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Rodrigues A. I.
,
Gomes M. E.
,
Leonor I. B.
, and
Reis R. L.
,
"
Exploring the osteoconductive effect of silanol groups by using human adipose stem cells
",
Journal of Tissue Engineering and Regenerative Medicine
, vol. 6, pp. 33-33, doi:
10.1002/term.1608
, 2012.
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RepositoriUM
Carvalho P. P.
,
Gimble J. M.
,
Dias I. R.
,
Gomes M. E.
, and
Reis R. L.
,
"
Translating human Adipose-derived Stem Cells (hASCs) to Clinical Practice requires standardization of isolation and culture protocols
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TERM STEM
, 2012.
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RepositoriUM
Rodrigues M. T.
,
Lee S. J.
,
Gomes M. E.
,
Reis R. L.
,
Atala A.
, and
Yoo J.
,
"
Amniotic Fluid-derived Stem Cells as a Cell Source for Bone Tissue Engineering
",
Tissue Engineering
, vol. 18, issue 23/24, pp. 2518-2527, doi:
10.1089/ten.tea.2011.0672
, 2012.
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RepositoriUM
Silva T. H.
,
Alves A.
,
Popa E. G.
,
Reys L. L.
,
Gomes M. E.
,
Sousa R. A.
,
Silva S. S.
,
Mano J. F.
, and
Reis R. L.
,
"
Marine Algae Sulfated Polysaccharides for Tissue Engineering and Drug Delivery Approaches
",
BioMatter
, vol. 2, issue 4, pp. 278-289, doi:
doi.org/10.4161/biom.22947
, 2012.
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RepositoriUM
Rodrigues M. T.
,
Lee B. K.
,
Lee S. J.
,
Gomes M. E.
,
Reis R. L.
,
Atala A.
, and
Yoo J.
,
"
The effect of differentiation stage of amniotic fluid stem cells on bone regeneration
",
Biomaterials
, vol. 33, issue 26, pp. 6069–6078, doi:
10.1016/j.biomaterials.2012.05.016
, 2012.
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RepositoriUM
Popa E. G.
,
Rodrigues M. T.
,
Coutinho D. F.
,
Oliveira M. B.
,
Mano J. F.
,
Reis R. L.
, and
Gomes M. E.
,
"
Cryopreservation of cell laden natural origin hydrogels for cartilage regeneration strategies
",
Soft Matter
, doi:
10.1039/c2sm26846a
, 2012.
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RepositoriUM
Coutinho D. F.
,
Santo V. E.
,
Caridade S. G.
,
Mano J. F.
,
Gomes M. E.
,
Neves N. M.
, and
Reis R. L.
,
"
Modulation of adipose tissue derived stem cells encapsulated in injectable multi-functional hydrogels
",
Journal of Tissue Engineering and Regenerative Medicine
, doi:
10.1002/term.1608
, 2012.
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RepositoriUM
Mihaila S. M.
,
Frias A. M.
,
Pirraco R. P.
,
Rada T.
,
Reis R. L.
,
Gomes M. E.
, and
Marques A. P.
,
"
Human Adipose Tissue-Derived SSEA-4 SubPopulation Multi-Differentiation Potential Towards the Endothelial and Osteogenic Lineages
",
Tissue Engineering part A
, vol. 19, issue 1-2, pp. 235-246, doi:
10.1089/ten.tea.2012.0092
, 2012.
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RepositoriUM
Rodrigues M. T.
,
Gonçalves A. I.
,
Reis R. L.
, and
Gomes M. E.
,
"
Bioengineering a tendon-like substitute: adult stem cell behavior in aligned fibrous scaffolds and stimulating culturing environments
",
Society for Biomaterials 2013
, 2012.
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Mihaila S. M.
,
Gaharwar A. K.
,
Reis R. L.
,
Marques A. P.
,
Gomes M. E.
, and
Khademhosseini A.
,
"
Photocrosslinkable Kappa-Carrageenan Hydrogels for Tissue Engineering Applications
",
Advanced Healthcare Materials
, doi:
10.1002/adhm.201200317
, 2012.
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2013
Carvalho P. P.
,
Gomes M. E.
,
Reis R. L.
, and
Gimble J. M.
,
"
Adipose Tissue-Derived MSCs: Moving to the Clinic
",
Mesenchymal Stromal Cells: Biology and Clinical Applications
,
Springer
,
New York
, pp. 663-681, doi:
10.1007/978-1-4614-5711-4_38
, 2013.
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Costa P. F.
,
Martins A.
,
Vaquette C.
,
Neves N. M.
,
Gomes M. E.
,
Hutmacher D. W.
, and
Reis R. L.
,
"
Single-step method and device for the generation of stratified tubular tissue substitutes
",
EP2788469 (A1) 2014-10-15
, 2013.
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Duarte A. R. C.
,
Santo V. E.
,
Alves A.
,
Silva S. S.
,
Moreira-Silva J.
,
Silva T. H.
,
Marques A. P.
,
Gomes M. E.
,
Sousa R. A.
,
Mano J. F.
, and
Reis R. L.
,
"
Unleashing the potential of supercritical fluids for polymer processing in tissue engineering and regenerative medicine
",
The Journal of Supercritical Fluids
, vol. 79, pp. 177-185, doi:
10.1016/j.supflu.2013.01.004
, 2013.
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Santo V. E.
,
Gomes M. E.
,
Mano J. F.
, and
Reis R. L.
,
"
Controlled Release Strategies for Bone, Cartilage, and Osteochondral Engineering-Part I: Recapitulation of Native Tissue Healing and Variables for the Design of Delivery Systems
",
TISSUE ENGINEERING: Part B
, vol. 19, issue 4, doi:
10.1089/ten.teb.2012.0138
, 2013.
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Silva S. S.
,
Popa E. G.
,
Gomes M. E.
,
Cerqueira M. T.
,
Marques A. P.
,
Caridade S. G.
,
Teixeira P.
,
Sousa C.
,
Mano J. F.
, and
Reis R. L.
,
"
An investigation of the potential application of chitosan/aloe-based membranes for regenerative medicine
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Acta Biomaterialia
, doi:
10.1016/j.actbio.2013.02.027
, 2013.
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Requicha J. F.
,
Leonor I. B.
,
Muñoz F.
,
Moura T.
,
Azevedo J. M.
,
Gomes M. E.
,
Reis R. L.
, and
Viegas C. A. A.
,
"
Tissue engineered scaffold for periodontal regeneration: laboratorial and preclinical characterization
",
I Simpósio Inter-Universitário de Investigação em Medicina Dentária
, 2013.
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Leal A. I.
,
Caridade S. G.
,
Ma J.
,
Yu N.
,
Gomes M. E.
,
Reis R. L.
,
Jansen J. A.
,
Walboomers X. F.
, and
Mano J. F.
,
"
Asymmetric PDLLA membranes containing Bioglass® for guided tissue Regeneration: characterization and in-vitro biological behavior
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Dental Materials
, vol. 29, issue 4, pp. 427-436, doi:
10.1016/j.dental.2013.01.009
, 2013.
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Custódio C. A.
,
Santo V. E.
,
Gomes M. E.
,
Reis R. L.
, and
Mano J. F.
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Engineering Functional Microparticles to Fabricate Instructive Cell Microenvironments
",
Society For Biomaterials - 2013 Annual Meeting & Exposition
, 2013.
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Mihaila S. M.
,
Popa E. G.
,
Reis R. L.
,
Marques A. P.
, and
Gomes M. E.
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3D hydrogel fibers based system to design heterotypic bone vascularization approaches
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Society for Biomaterials (SFB)
, 2013.
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Carvalho P. P.
,
Gimble J. M.
,
Dias I. R.
,
Gomes M. E.
, and
Reis R. L.
,
"
Xeno-free enzymatic products for the isolation of human adipose-derived stromal/stem cells
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Tissue Eng Part C Methods
, vol. 19, issue 6, pp. 473-478, doi:
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Link D. P.
,
Gardel L. S.
,
Correlo V. M.
,
Gomes M. E.
, and
Reis R. L.
,
"
Osteogenic properties of starch poly(e-caprolactone) (SPCL) fiber meshes loaded with osteoblast-like cells in a rat critical-sized cranial defect
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Rodrigues A. I.
,
Oliveira M. B.
,
Mano J. F.
,
Gomes M. E.
,
Leonor I. B.
, and
Reis R. L.
,
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Synergistic effect of silicon and calcium ions on osteogenic differentiation of human adipose stem cells
",
Annual Meeting of the Society for Biomaterials
, 2013.
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Gaharwar A. K.
,
Mihaila S. M.
,
Swami A.
,
Patel A.
,
Sant A.
,
Reis R. L.
,
Marques A. P.
,
Gomes M. E.
, and
Khademhosseini A.
,
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Bioactive Silicate Nanoplatelets for Osteogenic Differentiation of Human Mesenchymal Stem Cells.
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Advanced Materials
, doi:
10.1002/adma.201300584
, 2013.
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RepositoriUM
Duarte A. R. C.
,
Santo V. E.
,
Alves A.
,
Silva S. S.
,
Moreira-Silva J.
,
Silva T. H.
,
Marques A. P.
,
Gomes M. E.
,
Sousa R. A.
,
Mano J. F.
, and
Reis R. L.
,
"
Unleashing the potential of supercritical fluids for polymer processing in tissue engineering and regenerative medicine
",
10th International Symposium on Supercritical Fluids
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10.1016/j.supflu.2013.01.004
, 2013.
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RepositoriUM
Custódio C. A.
,
Santo V. E.
,
Oliveira M. B.
,
Gomes M. E.
,
Reis R. L.
, and
Mano J. F.
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Gonçalves A. I.
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Rodrigues M. T.
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Controlled Release Strategies for Bone, Cartilage, and Osteochondral Engineering—Part II: Challenges on the Evolution from Single to Multiple Bioactive Factor Delivery
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Santo V. E.
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Silva S. S.
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Rada T.
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Chondrogenic Potential of Two hASCs Subpopulations Loaded onto Gellan Gum Hydrogel Evaluated in a Nude Mice Model
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Combination of aloe vera improves the biological performance of chitosan membranes for skin tissue repair
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Development of an Injectable bi-Layered System For Platelet Lysates Sustained Delivery in Support of Periodontal Tissue Regeneration
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Carvalho P. P.
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Undifferentiated human adipose-derived stromal/stem cells loaded onto wet-spun starch-polycaprolactone scaffolds enhance bone regeneration: Nude mice calvarial defect in vivo study
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Popa E. G.
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Functionalized Microparticles Producing Scaffolds in Combination with Cells
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Serum total and bone alkaline phosphatase levels and their correlation with serum minerals over the lifespan of sheep. Acta Veterinaria Hungarica
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Gonçalves A. I.
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2014
Requicha J. F.
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Gardel L. S.
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Assessing the repair of critical size bone defects performed in a goat tibia model using tissue-engineered constructs cultured in a bidirectional flow perfusion bioreactor
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Popa E. G.
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Platelet lysate membranes as new autologous templates for tissue engineering applications
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Popa E. G.
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Costa P. F.
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Automating the processing steps for obtaining bone tissue engineered substitutes: from imaging tools to bioreactors.
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Amphiphilic beads as depots for sustained drug release integrated into fibrillar scaffold
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Costa P. F.
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Biofabrication of customized bone grafts by combination of additive manufacturing and bioreactor knowhow
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Bone marrow stromal cells on a three-dimensional bioactive fiber mesh undergo osteogenic differentiation in the absence of osteogenic media supplements: The effect of silanol groups
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Mihaila S. M.
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Fabrication of endothelial cell-laden carrageenan microfibers for microvascularized bone tissue engineering applications
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Mihaila S. M.
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The osteogenic differentiation of SSEA-4 sub-population of human adipose derived stem cells using silicate nanoplatelets
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