Bioactive Silicate Nanoplatelets for Osteogenic Differentiation of Human Mesenchymal Stem Cells.

last updated: 2013-06-14
TitleBioactive Silicate Nanoplatelets for Osteogenic Differentiation of Human Mesenchymal Stem Cells.
Publication TypePapers in Scientific Journals
Year of Publication2013
AuthorsGaharwar A. K., Mihaila S. M., Swami A., Patel A., Sant A., Reis R. L., Marques A. P., Gomes M. E., and Khademhosseini A.
Abstract

Novel silicate nanoplatelets that induce osteogenic differentiation of human mesenchymal stem cells (hMSCs) in the absence of any osteoinductive factor are reported. The presence of the silicate triggers a set of events that follows the temporal pattern of osteogenic differentiation. These findings underscore the potential applications of these silicate nanoplatelets in designing bioactive scaffolds for musculoskeletal tissue engineering.
JournalAdvanced Materials
Date Published2013-05-01
PublisherWILEY-VCH Verlag GmbH & Co.
DOI10.1002/adma.201300584
URLhttp://onlinelibrary.wiley.com/doi/10.1002/adma.201300584/abstract
Keywordsosteogenic differentiation, osteoinductive, silicate nanoplatelets, Stem cells
RightsrestrictedAccess
Peer reviewedyes
Statuspublished

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