Magnetic-responsive hydrogels for cartilage tissue engineering

Cell engineering approaches where MNPs are
incorporated within three-dimensional constructs, such as scaffolds or
hydrogels may constitute a novel and attractive approach towards the
development of a magnetically-responsive system. These systems
would enable remote controlled actions over tissue engineered constructs
in vitro and in vivo. Moreover, growing evidence suggests that
the application of a magnetic field may enhance biological performance
over commonly used static culture conditions providing stimulation for
cell proliferation, migration and differentiation. In this work we analyze
the role of magnetic stimulation on the behavior of human adipose
derived stem cells (hASCs) laden in k-carrageenan hydrogels aiming at
cartilage tissue engineering approaches.