Papers in Scientific Journals (36)
Bakht S. M., Pardo A., Gómez-Florit M., Caballero D., Kundu S. C., Reis R. L., Domingues R. M. A., and Gomes M. E.,
"Human Tendon-on-Chip: Unveiling the Effect of Core Compartment-T Cell Spatiotemporal Crosstalk at the Onset of Tendon Inflammation",
Advanced Science, pp. 2401170, doi:
10.1002/advs.202401170, 2024.
Teixeira S. P. B., Pardo A., Bakht S. M., Gómez-Florit M., Reis R. L., Gomes M. E., and Domingues R. M. A.,
"Guiding Stem Cell Tenogenesis by Modulation of Growth Factor Signaling and Cell-Scale Biophysical Cues in Bioengineered Constructs",
Advanced Functional Materials, pp. 2312961, doi:
10.1002/adfm.202312961, 2024.
Monteiro R. F., Bakht S. M., Gómez-Florit M., Stievani F. C., Alves A. L. G., Reis R. L., Gomes M. E., and Domingues R. M. A.,
"Writing 3D In Vitro Models of Human Tendon within a Biomimetic Fibrillar Support Platform",
Acs Applied Materials & Interfaces, vol. 15, issue 44, pp. 50598-50611, 2023.
Graça A. L., Domingues R. M. A., Gómez-Florit M., and Gomes M. E.,
"Platelet-Derived Extracellular Vesicles Promote Tenogenic Differentiation of Stem Cells on Bioengineered Living Fibers",
International Journal Of Molecular Sciences, vol. 24, issue 4, pp. 1-18, doi:
10.3390/ijms24043516, 2023.
Pardo A., Bakht S. M., Gomez-Florit M., Rial R., Monteiro R., Teixeira S. P. B., Taboada P., Reis R. L., Domingues R. M. A., and Gomes M. E.,
"Magnetically-Assisted 3D Bioprinting of Anisotropic Tissue-Mimetic Constructs",
Advanced Functional Materials, issue 2208940, doi:
10.1002/adfm.202208940, 2022.
Bianchi E., Faccendini A., Del Favero E., Ricci C., Caliogna L., Vigani B., Pavesi F., Perotti C., Domingues R. M. A., Gomes M. E., Rossi S., and Sandri G.,
"Topographical and Compositional Gradient Tubular Scaffold for Bone to Tendon Interface Regeneration",
pharmaceutics, vol. 14, pp. 2153, doi:
10.3390/pharmaceutics14102153, 2022.
Fernández-Garibay X., Gómez-Florit M., Domingues R. M. A., Gomes M. E., Fernández-Costa J. M., and Ramón-Azcón J.,
"Xeno-free bioengineered human skeletal muscle tissue using human platelet lysate-based hydrogels",
Biofabrication, vol. 14, pp. 045015, doi:
10.1088/1758-5090/ac8dc8, 2022.
Calejo I., Labrador-Rached C. J., Gómez-Florit M., Docheva D., Reis R. L., Domingues R. M. A., and Gomes M. E.,
"Bioengineered 3D Living Fibers as In Vitro Human TissueModels of Tendon Physiology and Pathology",
Adv. Healthcare Mater, vol. 11, issue 15, pp. 1-14, doi:
10.1002/adhm.202102863, 2022.
Ribeiro J. P., Domingues R. M. A., Babo P. S., Nogueira L., Reseland J., Reis R. L., Gómez-Florit M., and Gomes M. E.,
"Highly elastic and bioactive bone biomimetic scaffolds based on platelet lysate and biomineralized cellulose nanocrystals",
Carbohydrate Polymers, vol. 292, issue 15, pp. 119638, doi:
10.1016/j.carbpol.2022.119638, 2022.
Graça A. L., Gómez-Florit M., Osório H., Rodrigues M. T., Domingues R. M. A., Reis R. L., and Gomes M. E.,
"Controlling the fate of regenerative cells with engineered platelet-derived extracellular vesicles",
Nanoscale, vol. 14, issue 17, pp. 6543-6556, doi:
10.1039/D1NR08108J, 2022.
Graça A. L., Domingues R. M. A., Calejo I., Gómez-Florit M., and Gomes M. E.,
"Therapeutic Effects of Platelet-Derived Extracellular Vesicles in a Bioengineered Tendon Disease Model",
International Journal of Molecular Sciences, vol. 23, issue 6, pp. 1-16, doi:
10.3390/ijms23062948, 2022.
Bakht S. M., Gómez-Florit M., Lamers T., Reis R. L., Domingues R. M. A., and Gomes M. E.,
"3D Bioprinting of Miniaturized Tissues Embedded in Self-Assembled Nanoparticle-Based Fibrillar Platforms",
Advanced Functional Materials, vol. 31, issue 46, pp. 2104245-2104245, doi:
10.1002/adfm.202104245, 2021.
Chahal A. S., Gómez-Florit M., Domingues R. M. A., Gomes M. E., and Tiainen H.,
"Human Platelet Lysate-Loaded Poly(ethylene glycol) Hydrogels Induce Stem Cell Chemotaxis In Vitro",
Biomacromolecules, vol. 22, issue 8, pp. 3486-3496, doi:
10.1021/acs.biomac.1c00573, 2021.
Vilaça A., Domingues R. M. A., Tiainen H., Mendes B. B., Barrantes A., Reis R. L., Gomes M. E., and Gómez-Florit M.,
"Multifunctional Surfaces for Improving Soft Tissue Integration",
Advanced Healthcare Materials, vol. 10, issue 8, pp. 2001985, doi:
10.1002/adhm.202001985, 2021.
Teixeira S. P. B., Domingues R. M. A., Babo P. S., Berdecka D., Miranda M. S., Gomes M. E., Peppas N. A., and Reis R. L.,
"Epitope‐Imprinted Nanoparticles as Transforming Growth Factor‐β3 Sequestering Ligands to Modulate Stem Cell Fate",
Advanced Functional Materials, vol. 31, issue 4, pp. 2003934, doi:
10.1002/adfm.202003934, 2021.
Mendes B. B., Daly A. C., Reis R. L., Domingues R. M. A., Gomes M. E., and Burdick J. A.,
"Injectable hyaluronic acid and platelet lysate-derived granular hydrogels for biomedical applications",
Acta Biomaterialia, pp. in press, doi:
10.1016/j.actbio.2020.10.040, 2020.
Mendes B. B., Gómez-Florit M., Araújo A. C., Prada J., Babo P. S., Domingues R. M. A., Reis R. L., and Gomes M. E.,
"Intrinsically bioactive cryogels based on platelet lysate nanocomposites for hemostasis applications. ",
Biomacromolecules, doi:
10.1021/acs.biomac.0c00787, 2020.
Mendes B. B., Gómez-Florit M., Osório H., Vilaça A., Domingues R. M. A., Reis R. L., and Gomes M. E.,
"Cellulose nanocrystals of variable sulfation degrees can sequester specific platelet lysate-derived biomolecules to modulate stem cell response",
Chemical Communications, vol. 56, issue 50, pp. 6882-6885, doi:
10.1039/D0CC01850C, 2020.
Echave M. C., Domingues R. M. A., Gómez-Florit M., Pedraz J. L., Reis R. L., Orive G., and Gomes M. E.,
"Biphasic Hydrogels Integrating Mineralized and Anisotropic Features for Interfacial Tissue Engineering",
Acs Applied Materials & Interfaces, vol. 11, issue 51, pp. 47771-47784, doi:
10.1021/acsami.9b17826, 2019.
Tomás A. R., Gonçalves A. I., Paz E., Freitas P., Reis R. L., Domingues R. M. A., and Gomes M. E.,
"Magneto-mechanical actuation of magnetic responsive fibrous scaffolds boosts tenogenesis of human adipose stem cells",
Nanoscale, doi:
10.1039/c9nr04355a, 2019.
Mendes B. B., Gómez-Florit M., Hamilton A., Detamore M., Domingues R. M. A., Reis R. L., and Gomes M. E.,
"Human platelet lysate-based nanocomposite bioink for bioprinting hierarchical fibrillar structures",
Biofabrication, doi:
10.1088/1758-5090/ab33e8, 2019.
Silva C. R., Babo P. S., Mithieux S. M., Domingues R. M. A., Reis R. L., Gomes M. E., and Weiss A.,
"Tuneable cellulose nanocrystal and tropoelastin-laden hyaluronic acid hydrogels",
Journal of Biomaterials Applications, vol. 34, issue 4, pp. 560 – 572, doi:
10.1177/0885328219859830, 2019.
Almeida H., Domingues R. M. A., Mithieux S. M., Pires R. A., Gonçalves A. I., Gómez-Florit M., Reis R. L., Weiss A. S., and Gomes M. E.,
"Tropoelastin coated tendon biomimetic scaffolds promote stem cell tenogenic commitment and deposition of elastin-rich matrix",
Acs Applied Materials & Interfaces, doi:
10.1021/acsami.9b04616, 2019.
Costa-Almeida R., Calejo I., Altieri R., Domingues R. M. A., Giordano E., Reis R. L., and Gomes M. E.,
"Exploring platelet lysate hydrogel-coated suture threads as biofunctional composite living fibers for cell delivery in tissue repair",
Biomedical Materials, doi:
10.1088/1748-605X/ab0de6, 2019.
Araújo-Custódio S., Gómez-Florit M., Tomás A. R., Mendes B. B., Babo P. S., Mithieux S. M., Weiss A. S., Domingues R. M. A., Reis R. L., and Gomes M. E.,
"Injectable and Magnetic Responsive Hydrogels with Bioinspired Ordered Structures",
ACS Biomaterials Science and Engineering, vol. 5, issue 3, pp. 1392-1404, doi:
10.1021/acsbiomaterials.8b01179, 2019.
Silva E. D., Babo P. S., Costa-Almeida R., Domingues R. M. A., Mendes B. B., Paz E., Freitas P., Rodrigues M. T., Granja P. L., and Gomes M. E.,
"Multifunctional magnetic-responsive hydrogels to engineer tendon-to-bone interface",
Nanomedicine: Nanotechnology, Biology and Medicine, vol. 14, issue 7, pp. 2375-2385, doi:
10.1016/j.nano.2017.06.002, 2018.
Mendes B. B., Gómez-Florit M., Pires R. A., Domingues R. M. A., Reis R. L., and Gomes M. E.,
"Human-based fibrillar nanocomposite hydrogels as bioinstructive matrices to tune stem cell behavior",
Nanoscale, vol. 10, issue 36, pp. 17388-17401, doi:
10.1039/C8NR04273J, 2018.
Silva C. F., Babo P. S., Gulino M., Costa L., Oliveira J. M., Silva-Correia J., Domingues R. M. A., Reis R. L., and Gomes M. E.,
"Injectable and tunable hyaluronic acid hydrogels releasing chemotactic and angiogenic growth factors for endodontic regeneration",
Acta Biomaterialia, doi:
10.1016/j.actbio.2018.07.035, 2018.
Pesqueira T., Costa-Almeida R., Mithieux S. M., Babo P. S., Franco A. R., Mendes B. B., Domingues R. M. A., Freitas P., Reis R. L., Gomes M. E., and Weiss A. S.,
"Engineering magnetically responsive tropoelastin spongy-like hydrogels for soft tissue regeneration",
Journal Of Materials Chemistry B, doi:
10.1039/C7TB02035J, 2018.
Costa-Almeida R., Domingues R. M. A., Fallahi A., Avci H., Yazdi I. K., Akbari M., Reis R. L., Tamayol A., Gomes M. E., and Khademhosseini A.,
"Cell-laden composite suture threads for repairing damaged tendons",
Journal Of Tissue Engineering And Regenerative Medicine, doi:
10.1002/term.2605, 2017.
Neves L. S., Babo P. S., Gonçalves A. I., Costa-Almeida R., Caridade S. G., Mano J. F., Domingues R. M. A., Rodrigues M. T., Reis R. L., and Gomes M. E.,
"Injectable Hyaluronic Acid Hydrogels Enriched with Platelet Lysate as a Cryostable Off-the-Shelf System for Cell-Based Therapies",
Regenerative Engineering and Translational Medicine, vol. 3, issue 2, pp. 53-69 , doi:
10.1007/s40883-017-0029-8, 2017.
Domingues R. M. A., Silva M., Gershovich P., Betta S., Babo P. S., Caridade S. G., Mano J. F., Motta A., Reis R. L., and Gomes M. E.,
"Development of Injectable Hyaluronic Acid/Cellulose Nanocrystals Bionanocomposite Hydrogels for Tissue Engineering Applications",
Bioconjugate Chemistry, doi:
10.1021/acs.bioconjchem.5b00209, 2015.
Review Paper (9)
Pardo A., Gómez-Florit M., Davidson M. D., Öztürk-Öncel M. O., Domingues R. M. A., Burdick J. A., and Gomes M. E.,
"Hierarchical Design of Fibrous Tissue-Mimetic Scaffolds",
Adv Healthc Mater . , doi:
10.1002/adhm.202303167, 2024.
Teixeira S. P. B., Reis R. L., Peppas N. A., Gomes M. E., and Domingues R. M. A.,
"Epitope-imprinted polymers: Design principles of synthetic binding partners for natural biomacromolecules",
Science Advances, vol. 7, issue 44, pp. eabi9884, doi:
10.1126/sciadv.abi9884, 2021.
Bakht S. M., Pardo A., Gómez-Florit M., Reis R. L., Domingues R. M. A., and Gomes M. E.,
"Engineering next-generation bioinks with nanoparticles: moving from reinforcement fillers to multifunctional nanoelements",
Journal of Material Chemistry B, 2021, issue 25, pp. 5025–5038, doi:
10.1039/D1TB00717C, 2021.
Pardo A., Gómez-Florit M., Barbosa S., Taboada P., Domingues R. M. A., and Gomes M. E.,
"Magnetic Nanocomposite Hydrogels for Tissue Engineering: Design Concepts and Remote Actuation Strategies to Control Cell Fate",
ACS Nano, issue 15, pp. 175-209, doi:
10.1021/acsnano.0c08253, 2021.
Gómez-Florit M., Pardo A., Domingues R. M. A., Graça A. L., Babo P. S., Reis R. L., and Gomes M. E.,
"Natural-Based Hydrogels for Tissue Engineering Applications",
Molecules, vol. 25, issue 24, pp. 5858, doi:
10.3390/molecules25245858, 2020.
Miranda M. S., Rodrigues M. T., Domingues R. M. A., Torrado E., Reis R. L., Pedrosa J., and Gomes M. E.,
"Exploring inhalable polymeric dry powders for anti-tuberculosis drug delivery",
Materials Science and Engineering: C, vol. 93, issue 1, pp. 1090-1103, doi:
10.1016/j.msec.2018.09.004, 2018.
Mendes B. B., Gómez-Florit M., Babo P. S., Domingues R. M. A., Reis R. L., and Gomes M. E.,
"Blood derivatives awaken in regenerative medicine strategies to modulate wound healing",
Advanced Drug Delivery Reviews, vol. 129, pp. 376-393, doi:
10.1016/j.addr.2017.12.018, 2018.
Book Chapter (6)
Gonçalves A. I., Rodrigues M. T., Matos A. M., Almeida H., Gómez-Florit M., Domingues R. M. A., and Gomes M. E.,
"Multiscale Multifactorial Approaches for Engineering Tendon Substitutes",
Organ Tissue Engineering. Reference Series in Biomedical Engineering,
Eds. Eberli D., Lee S., and Traweger A.,
Springer, Cham, pp. 1-24, doi:
10.1007/978-3-030-18512-1_8-1, 2020.
Gómez-Florit M., Domingues R. M. A., Bakht S. M., Mendes B. B., Reis R. L., and Gomes M. E.,
"Natural materials",
Biomaterials Science (Fourth Edition) An Introduction to Materials in Medicine,
Eds. Wagner W. R., Sakiyama-Elbert S., Zhang G., and Yaszemski M. J.,
Academic Press, Elsevier, 4, pp. 361-375, doi:
10.1016/B978-0-12-816137-1.00026-X, 2020.
Rodrigues M. T., Domingues R. M. A., Reis R. L., and Gomes M. E.,
"Future Directions: What the Future Holds for TERM",
Encyclopedia of Tissue Engineering and Regenerative Medicine,
Eds. Reis R. L.,
Elsevier Inc., 1, vol. 1, pp. 1-7, doi:
https://doi.org/10.1016/B978-0-12-801238-3.11287-5, 2019.
Domingues R. M. A., Gonçalves A. I., Reis R. L., and Gomes M. E.,
"Bionanocrystals in tissue engineering strategies: tools for reinforcement, nanopatterning and/or nanostructuring of polymeric scaffolds and hydrogels",
Handbook of Intelligent Scaffolds for Regenerative Medicine,
Eds. Khang G.,
Pan Stanford, 2nd, pp. 413-438, 2017.
Santos M. L., Rodrigues M. T., Domingues R. M. A., Reis R. L., and Gomes M. E.,
"Biomaterials as Tendon and Ligament Substitutes: Current Developments",
Regenerative Strategies for the Treatment of Knee Joint Disabilities,
Eds. Oliveira J. M., and Reis R. L.,
Springer International Publishing, vol. 21, pp. 349-371, doi:
10.1007/978-3-319-44785-8_17, 2016.
Domingues R. M. A., Gonçalves A. I., Costa-Almeida R., Rodrigues M. T., Reis R. L., and Gomes M. E.,
"Fabrication of Hierarchical and Biomimetic Fibrous Structures to Support the Regeneration of Tendon Tissues",
Tendon Regeneration,
Eds. Gomes M. E., Reis R. L., and Rodrigues M. T.,
Elsevier, 1st, pp. 259–280, doi:
doi:10.1016/B978-0-12-801590-2.00010-7, 2015.
Invited Review Paper (3)
Öztuerk-Öncel M. Ö., Leal-Martínez B. H., Monteiro R. F., Gomes M. E., and Domingues R. M. A.,
"A dive into the bath: embedded 3D bioprinting of freeform in vitro models",
Biomaterials Science, vol. 11, pp. 5462-5473, doi:
10.1039/D3BM00626C, 2023.
Teixeira S. P. B., Domingues R. M. A., Shevchuk M., Gomes M. E., Peppas N. A., and Reis R. L.,
"Biomaterials for Sequestration of Growth Factors and Modulation of Cell Behavior",
Advanced Functional Materials, vol. 30, issue 44, pp. 1909011, doi:
10.1002/adfm.201909011, 2020.
Gomes M. E., Rodrigues M. T., Domingues R. M. A., and Reis R. L.,
"Tissue Engineering and Regenerative Medicine: New Trends and Directions-A Year in Review.",
Tissue Engineering Part B: Reviews, vol. 23, issue 3, pp. 211-224, doi:
10.1089/ten.teb.2017.0081, 2017.
Conference Abstract -ISI Web of Science Indexed (6)
Teixeira S. P. B., Pardo A., Bakht S. M., Gómez-Florit M., Reis R. L., Gomes M. E., and Domingues R. M. A.,
"3D Biomimetic Constructs Steer Stem Cell Commitment By Synergistic Modulation Of Biophysical Cues And Growth Factor Signalling",
Orthopaedic Proceedings, vol. 106-B, issue SUPP_1, pp. 13, doi:
10.1302/1358-992X.2024.1.013, 2024.
Monteiro R. F., Bakht S. M., Gómez-Florit M., Reis R. L., Gomes M. E., and Domingues R. M. A.,
"3D Writing of Multicellular Tendon-On-Cnc-Chip Models",
Orthopaedic Proceedings, vol. 106-B No.SUPP_2, pp. 15-15, doi:
10.1302/1358-992X.2024.2.015, 2024.
Bakht S. M., Pardo A., Reis R. L., Domingues R. M. A., and Gomes M. E.,
"Combining Magnetically-Assisted and Matrix-Assisted 3D Bioprinting for Anisotropic Tissue Engineering",
Orthopaedic proceedings, vol. 106-B(SUPP_2), pp. 59, doi:
10.1302/1358-992X.2024.2.059, 2024.
Domingues R. M. A., Alves da Silva, ML, Gershovich P., Betta S., Babo P. S., Caridade S. G., Mano J. F., Motta A., Reis R. L., and Gomes M. E.,
"Injectable hyaluronic acid bionanocomposite hydrogels: from biomaterial development to biological performance outcomes",
Frontiers in Bioengineering and Biotechnology, doi:
10.3389/conf.FBIOE.2016.01.01964, 2016.
Conference Paper -ISI Web of Science Indexed (1)
Mendes B. B., Gómez-Florit M., Randall L., Babo P. S., Costa-Almeida R., Detamore M. S., Domingues R. M. A., Reis R. L., and Gomes M. E.,
"Human-based nanocomposite cryogels for hemostatic and wound healing applications",
Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium, vol. 40, pp. 597, 2019.
Comunications - Poster (6)
Miranda M. S., Rodrigues M. T., Domingues R. M. A., Gonçalves C., Torrado E., Reis R. L., Pedrosa J., and Gomes M. E.,
"Targeting macrophages with inhalable microparticulate system for the treatment of tuberculosis",
Chem2Nature - Second School, 2017.
Miranda M. S., Domingues R. M. A., Rodrigues M. T., Costa R. R., Gonçalves C., Carvalho A., Reis R. L., Pedrosa J., and Gomes M. E.,
"Development of inhalable SPIONs-in microparticle system for delivery of an anti-tuberculosis drug",
TERMSTEM2016, 2016.
Silva E. D., Babo P. S., Costa-Almeida R., Domingues R. M. A., Mendes B. B., Rodrigues M. T., Granja P. L., and Gomes M. E.,
"Multifunctional magnetic responsive hydrogels to engineer tendon to bone interface",
TermStem 2016, 2016.
Comunication - Oral (3)
Miranda M. S., Domingues R. M. A., Rodrigues M. T., Costa R. R., Gonçalves C., Carvalho A., Reis R. L., Pedrosa J., and Gomes M. E.,
"Magneto-responsive gelatin microparticulate systems for targeted pulmonary delivery of anti-tuberculosis drugs",
Chem2Nature First School, 2016.
Patent (2)