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Comunications - Poster
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Patent
2004
Noemi C.
,
Sanchez A.
,
Fernandez-Megia E.
,
Novoa-Carballal R.
, and
Alonso M.
,
"
Chitosan nanoparticles for the delivery of plasmid DNA: Preparation and characterisation
",
European Journal of Pharmaceutical Sciences
, issue 23, pp. S55, 2004.
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2005
Fernandez-Megia E.
,
Novoa-Carballal R.
,
Emilio Q.
, and
Riguera R.
,
"
Optimal routine conditions for the determination of the degree of acetylation of chitosan by 1H-NMR
",
Carbohydrate Polymers
, vol. 61, pp. 155, 2005.
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Aktas Y.
,
Yemisci, M.
,
Andrieux K.
,
Gursoy-Ozdemir Y.
,
Alonso M.
,
Fernandez-Megia E.
,
Novoa-Carballal R.
,
Quiñoa E.
,
Riguera R.
,
Sargon M. F.
,
Çelik H.
,
Demir H.
,
Hıncal A. S.
,
Dalkara T.
,
Y., Capan Y.
, and
Couvreur P.
,
"
Development and Brain Delivery of Chitosan-PEG Nanoparticles Functionalized with the Monoclonal Antibody OX26
",
Bioconjugate Chemistry
, vol. 16, pp. 1503, 2005.
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2006
Prego C.
,
Torres D.
,
Fernandez-Megia E.
,
Novoa-Carballal R.
,
Emilio Q.
, and
Alonso M.
,
"
Chitosan-PEG Nanocapsules as New Carriers for Oral Peptide Delivery
",
Journal of the Controlled Release Society
, vol. 11, pp. 299, 2006.
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2007
Fernandez-Megia E.
,
Novoa-Carballal R.
,
Emilio Q.
, and
Riguera R.
,
"
Conjugation of Bioactive Ligands to PEG-grafted Chitosan at the Distal End of PEG
",
Biomacromolecules
, issue 8, pp. 833, 2007.
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2009
Noemi C.
,
Magnus K. - H.
,
Novoa-Carballal R.
,
Fernandez-Megia E.
,
Riguera R.
, and
Alonso M.
,
"
Ionically Crosslinked Chitosan Nanoparticles as Gene Delivery Systems: Effect of PEGylation Degree on In Vitro and In Vivo Gene Transfer
",
Journal of Biomedical Nanotechnology
, vol. 5, pp. 162, 2009.
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Karatas. H.
,
Aktas Y.
,
Gursoy-Ozdemir Y.
,
Bodur E.
,
Yemisci M.
,
Caba S.
,
Vural A.
,
Pinarbasli O.
,
Capan Y.
,
Fernandez-Megia E.
,
Novoa-Carballal R.
,
Riguera R.
,
Andrieux P.
,
Couvreur P.
, and
Dalkara T.
,
"
A Nanomedicine Transports a Peptide Caspase-3 Inhibitor across the Blood–Brain Barrier and Provides Neuroprotection
",
The Journal of Neuroscience
, issue 29, pp. 13761, 2009.
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Fernandez-Megia E.
,
Correa J.
,
Novoa-Carballal R.
, and
Riguera R.
,
"
Paramagnetic NMR Relaxation in Polymeric Matrixes: Sensitivity Enhancement and Selective Suppression of Embedded Species (1H and 13C PSR Filter)
",
Journal of the American Chemical Society
, issue 129, pp. 15164, 2009.
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O. P.
,
Atkas Y.
,
T. D.
,
Alonso M.
,
Fernandez-Megia E.
,
Novoa-Carballal R.
,
Riguera R.
,
P. C.
, and
Y. C.
,
"
Preparation and evaluation of alpha-phenyl-n-tert-butyl nitrone (PBN)-encapsulated chitosan and PEGylated chitosan nanoparticles
",
Die Pharmazie
, vol. 29, pp. 13761, 2009.
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2010
Novoa-Carballal R.
,
Elin S.
,
Fernandez-Megia E.
,
Riguera R.
, and
Widmalm G.
,
"
The Dynamics of GATG Glycodendrimers by NMR Diffusion and Quantitative 13C Relaxation
",
Physical Chemistry Chemical Physics
, vol. 12, pp. 6587, 2010.
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Novoa-Carballal R.
,
Fernandez-Megia E.
, and
Riguera R.
,
"
Dynamics of Chitosan by 1H NMR Relaxation
",
Biomacromolecules
, vol. 11, pp. 2079, 2010.
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Novoa-Carballal R.
,
Fernandez-Megia E.
,
Carlos J.
, and
Riguera R.
,
"
NMR methods for unravelling the spectra of complex mixtures
",
Natural Products Reports
, vol. 28, pp. 78, 2010.
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Raviña M.
,
Cubillo E.
,
Olmeda D.
,
Novoa-Carballal R.
,
Novoa-Carballal R.
,
Fernandez-Megia E.
,
Riguera R.
,
Sanchez A.
,
Cano A.
, and
Alonso M.
,
"
Hyaluronic Acid/Chitosan-g-Poly(ethylene glycol) Nanoparticles for Gene Therapy: An Application for pDNA and siRNA Delivery
",
Pharmaceutical Research
, vol. 27, pp. 2544, 2010.
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2012
Novoa-Carballal R.
,
Riguera R.
, and
Fernandez-Megia E.
,
"
Chitosan Copolymers for Biopharmaceuticals
",
Chitosan-Based Systems for Biopharmaceuticals: Delivery, Targeting and Polymer Therapeutics
,
Wiley
, doi:
10.1002/978111996297
, 2012.
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Novoa-Carballal R.
, and
Muller A. H. E.
,
"
Synthesis of Polysaccharide-b-PEG copolymers by Oxime Click
",
Chemical Communication
, vol. 48, pp. 3781, 2012.
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2013
Novoa-Carballal R.
,
Pfaff A.
, and
Muller A. H. E.
,
"
Interpolyelectrolyte complexes with a polysaccharide corona from dextran-block-PDMAEMA diblock copolymers
",
Polymer Chemistry
, vol. 4, issue 4, doi:
10.1039/C3PY21088J
, 2013.
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Jakob F.
,
Pfaff A.
,
Novoa-Carballal R.
,
Rübsam H.
,
Becker T.
, and
Vogel R. F.
,
"
Structural and functional characterization of fructans produced by acetic acid bacteria
",
Carbohydrate Polymers
, vol. 92, pp. 1234, 2013.
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Novoa-Carballal R.
,
Dmitry V. P.
, and
Muller A. H. E.
,
"
Interpolyelectrolyte complexes based on hyaluronic acid-block-poly(ethylene glycol) and poly-L-lysine
",
Soft Matter
, vol. 9, pp. 4297, 2013.
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Torrecilla D.
,
Lozano M. V.
,
Lallana E.
,
Neissa J. I.
,
Novoa-Carballal R.
,
Vidal A.
,
Fernandez-Megia E.
,
Torres D.
,
Riguera R.
,
Alonso M.
, and
Dominguez F.
,
"
Anti-tumor efficacy of chitosan-g-poly(ethylene glycol) nanocapsules containing docetaxel: Anti-TMEFF-2 functionalized nanocapsules vs. non-functionalized nanocapsules
",
European Journal of Pharmaceutics and Biopharmaceutics
, vol. 83, pp. 330, 2013.
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Novoa-Carballal R.
,
Riguera R.
, and
Fernandez-Megia E.
,
"
Hydrophobic Domains in Aggregates of Chitosan are Favored at Low Degree of Acetylation and Molecular Weight
",
Polymer
, vol. 54, issue 8, pp. 2081, 2013.
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Novoa-Carballal R.
,
Riguera R.
, and
Fernandez-Megia E.
,
"
Disclosing an NMR-Invisible Fraction in Chitosan and PEGylated Copolymers and Its Role on the Determination of Degrees of Substitution
",
Molecular Phamaceutics
, vol. 10, issue 8, pp. 3225-3231, 2013.
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Novoa-Carballal R.
,
Reis R. L.
, and
Pashkuleva I.
,
"
Nanocarriers based on interpolyelectrolyte complexation of Sulphated polysaccharide-b- PEG diblock copolymers and PLL
",
Journal of Tissue engeneering and regenerative medicine
, vol. 7, pp. 45-45, doi:
10.1002/term.1822
, 2013.
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RepositoriUM
2014
Novoa-Carballal R.
,
Silva C.
,
Moller S.
,
Schnabelrauch M.
,
Reis R. L.
, and
Pashkuleva I.
,
"
Tunable nano-carriers from clicked glycosaminoglycan block copolymers
",
Journal of Materials Chemistry B
, vol. 2, issue 26, pp. 4177-4184, doi:
10.1039/C4TB00410H
, 2014.
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RepositoriUM
Ozturk K.
,
Fernandez-Megia E.
,
Novoa-Carballal R.
,
Riguera R.
,
Yemisci M.
,
Gurny R.
,
Dalkara T.
,
Couvreur P.
, and
Capan Y.
,
"
Comparative in vitro studies on PBN loaded nanoparticles prepared by biodegradable chitosan, PLGA polymers and their PEGylated block copolymers.
",
J. Drug. Del.. Sci. Tech.
, vol. 24, issue 2, pp. 148, 2014.
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Novoa-Carballal R.
,
Silva C.
,
Möller S.
,
Schnabelrauch M.
,
Reis R. L.
, and
Pashkuleva I.
,
"
Protein nano-carriers from clicked glycosaminoglycan block copolymers
",
ESB 2014 - 26th European Conference on Biomaterials
, 2014.
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Silva C.
,
Novoa-Carballal R.
,
Reis R. L.
, and
Pashkuleva I.
,
"
Real time analysis of the enzymatic digestion of chondroitin sulfate: role of the sulfation pattern
",
26th Annual Conference European Society of Biomaterials
, 2014.
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2015
Pires R. A.
,
Abul-Haija Y. M.
,
Soares da Costa D.
,
Novoa-Carballal R.
,
Reis R. L.
,
Ulijn R. V.
, and
Pashkuleva I.
,
"
Controlling Cancer Cell Fate Using Localized Biocatalytic Self-Assembly of an Aromatic Carbohydrate Amphiphile
",
Journal of the American Chemical Society
, vol. 137, issue 2, pp. 576-579, doi:
10.1021/ja5111893
, 2015.
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RepositoriUM
Silva C.
,
Novoa-Carballal R.
,
Reis R. L.
, and
Pashkuleva I.
,
"
Following the enzymatic digestion of chondroitin sulfate by a simple GPC analysis
",
Analytica Chimica Acta
, vol. 885, pp. 207-213, doi:
10.1016/j.aca.2015.05.034
, 2015.
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RepositoriUM
2016
Silva T. H.
,
Oliveira C.
,
Reys L. L.
,
Soares da Costa D.
,
Novoa-Carballal R.
,
Oliveira N. M.
,
Ferreira A. S.
,
Nunes C.
,
Silva S. S.
,
Martins A.
,
Coimbra M. A.
,
Mano J. F.
,
Neves N. M.
, and
Reis R. L.
,
"
BIOMEDICAL POTENTIAL OF FUCOIDAN, A SEAWEED SULFATED POLYSACCHARIDE: FROM A ANTICANCER AGENT TO A BUILDING BLOCK OF CELL ENCAPSULATING SYSTEMS FOR REGENERATIVE MEDICINE
",
10th World Biomaterials Congress
, 2016.
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Silva T. H.
,
Oliveira C.
,
Reys L. L.
,
Soares da Costa D.
,
Novoa-Carballal R.
,
Oliveira N. M.
,
Ferreira A. S.
,
Nunes C.
,
Silva S. S.
,
Martins A.
,
Coimbra M. A.
,
Mano J. F.
,
Neves N. M.
, and
Reis R. L.
,
"
Biomedical potential of fucoidan, a seaweed sulfated polysaccharide: from a anticancer agent to a building block of cell encapsulating systems for regenerative medicine
",
Front. Bioeng. Biotechnol
, pp. 221, doi:
10.3389/conf.FBIOE.2016.01.00221
, 2016.
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RepositoriUM
Brito A.
,
Soares da Costa D.
,
Novoa-Carballal R.
,
Reis R. L.
,
Pires R. A.
, and
Pashkuleva I.
,
"
Supramolecular hydrogels with tuned mechanical properties for tissue engineering
",
GENE2SKIN Conference and TERM STEM 2016
, 2016.
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da Silva L. P.
,
Pirraco R. P.
,
Santos T. C.
,
Novoa-Carballal R.
,
Cerqueira M. T.
,
Reis R. L.
,
Correlo V. M.
, and
Marques A. P.
,
"
Neovascularization Induced by the Hyaluronic Acid-Based Spongy-Like Hydrogels Degradation Products
",
ACS Applied Materials and Interfaces
, doi:
10.1021/acsami.6b11684
, 2016.
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Brito A.
,
Soares da Costa D.
,
Novoa-Carballal R.
,
Reis R. L.
,
Pires R. A.
, and
Pashkuleva I.
,
"
Synthesis of biofunctional supramolecular hydrogels by co-assembly of simple carbohydrate and peptide amphiphiles
",
Chem2Nature
, 2016.
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da Silva L. P.
,
Pirraco R. P.
,
Santos T. C.
,
Novoa-Carballal R.
,
Cerqueira M. T.
,
Reis R. L.
,
Correlo V. M.
, and
Marques A. P.
,
"
Hyaluronidase‐mediated degradation products of hyaluronic acid‐based spongylike hydrogels promote neovascularization
",
Chem2Nature Conference
, 2016.
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2017
Novoa-Carballal R.
,
Pérez-Martín, R.; Blanco S. M.;
,
Nunes C.
,
Coimbra M. A.
,
Silva T. H.
,
Reis R. L.
, and
José V. A.
,
"
By-products of Scyliorhinus canicula, Prionace glauca and Raja clavata: A valuable source of predominantly 6S sulfated chondroitin sulfate
",
Carbohydrate Polymers
, vol. 157, pp. 31-38, doi:
10.1016/j.carbpol.2016.09.050
, 2017.
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RepositoriUM
Oliveira C.
,
Ferreira A. S.
,
Novoa-Carballal R.
,
Nunes C.
,
Pashkuleva I.
,
Neves N. M.
,
Coimbra M. A.
,
Reis R. L.
,
Martins A.
, and
Silva T. H.
,
"
The Key Role of Sulfation and Branching on Fucoidan Antitumor Activity
",
Macromolecular Bioscience
, vol. 17, issue 5, pp. 1600340, doi:
10.1002/mabi.201600340
, 2017.
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RepositoriUM
Fontelo R.
,
Chandaluri C. G.
,
Shenhar R.
,
Soares da Costa D.
,
Reis R. L.
,
Novoa-Carballal R.
, and
Pashkuleva I.
,
"
Glycosaminoglycans incorporation on periodic block copolymer patterns for cell behaviour studies.
",
Chem2Nature First School
, 2017.
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Carvalho A. M.
,
Teixeira R.
,
Novoa-Carballal R.
,
Pires R. A.
,
Reis R. L.
, and
Pashkuleva I.
,
"
Redox-sensitive self-assembled glycosaminoglycans nanoparticles for targeted drug delivery
",
Chem2Nature Second School: Chemical Modification of Biomaterials and 'Living' Surfaces with Biopolymers Derivatives
, 2017.
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Brito A.
,
Soares da Costa D.
,
Novoa-Carballal R.
,
Abul-Haija Y. M.
,
Reis R. L.
,
Ulijn R. V.
,
Pires R. A.
, and
Pashkuleva I.
,
"
Biofunctional supramolecular hydrogels by co-assembly of simple carbohydrate and peptide amphiphiles
",
TERMIS
, 2017.
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Valcarcel J.
,
Novoa-Carballal R.
,
Pérez-Martín R. I.
,
Reis R. L.
, and
José V. A.
,
"
Glycosaminoglycans from marine sources as therapeutic agents
",
Biotechnology Advances
, vol. 35, issue 6, pp. 711-725, doi:
10.1016/j.biotechadv.2017.07.008
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RepositoriUM
Carvalho A. M.
,
Teixeira R.
,
Novoa-Carballal R.
,
Reis R. L.
, and
Pashkuleva I.
,
"
Glycosaminoglycans Micelles for Targeting Drug Delivery
",
ESB2017 - Translational activities for exploiting research on Biomaterials
, 2017.
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Silva C.
,
Carretero A. C.
,
Soares da Costa D.
,
Reis R. L.
,
Novoa-Carballal R.
, and
Pashkuleva I.
,
"
Design of protein delivery systems by mimicking extracellular mechanisms for protection of growth factors
",
Acta Biomaterialia
, vol. 63, pp. 283 - 293, doi:
10.1016/j.actbio.2017.08.042
, 2017.
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RepositoriUM
Carvalho A. M.
,
Teixeira R.
,
Novoa-Carballal R.
,
Reis R. L.
, and
Pashkuleva I.
,
"
Potential of thiol-amphiphile glycosaminoglycans as redox-sensitive nanoparticles
",
GluPor - Carcoidratos em Portugal e potencial de diferenciação internacional
, 2017.
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Brito A.
,
Soares da Costa D.
,
Novoa-Carballal R.
,
Abul-Haija Y. M.
,
Reis R. L.
,
Ulijn R. V.
,
Pires R. A.
, and
Pashkuleva I.
,
"
Supramolecular hydrogels based on the co-assembly of simple carbohydrates and peptide amphiphiles for biological applications
",
12ª Reunião do Grupo de Glúcidos
, 2017.
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López-Cebral R.
,
Novoa-Carballal R.
,
Oliveira J. M.
,
Silva T. H.
, and
Reis R. L.
,
High molecular weight chitosan, process for obtaining and uses thereof
, 2017.
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José V. A.
,
Noriega D.
,
Ramos P.
,
Valcarcel J.
,
Novoa-Carballal R.
,
Pastrana L.
,
Reis R. L.
, and
Ricardo P. M. I.
,
"
Optimization of high purity chitin and chitosan production from Illex argentinus pens by a combination of enzymatic and chemical processes
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Carbohydrate Polymers
, vol. 174, pp. 262-272, doi:
10.1016/j.carbpol.2017.06.070
, 2017.
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RepositoriUM
Fontelo R.
,
Chandaluri C. G.
,
Shenhar R.
,
Reis R. L.
,
Novoa-Carballal R.
, and
Pashkuleva I.
,
"
Periodic block copolymer patterns for fundamental biological studies
",
INTERNATIONAL SYMPOSIUM ON BIOINSPIRED MACROMOLECULAR SYSTEMS (ISBMS)
, 2017.
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Gomes M.
,
Lozano-Fernández T.
,
Gallego A.
,
Gonzalez-Fernández A.
,
Reis R. L.
,
Novoa-Carballal R.
, and
Pashkuleva I.
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"
Synthesis and anticoagulant activity of glycosaminoglycan copolymers
",
International Symposium on Bioinspired Macromolecular Systems
, 2017.
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Fontelo R.
,
Chandaluri C. G.
,
Shenhar R.
,
Reis R. L.
,
Novoa-Carballal R.
, and
Pashkuleva I.
,
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Periodic block copolymer patterns for fundamental biological studies
",
TERM STEM / FORECAST
, 2017.
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2018
Carvalho A. M.
,
Teixeira R.
,
Novoa-Carballal R.
,
Pires R. A.
,
Reis R. L.
, and
Pashkuleva I.
,
"
Redox-responsive micellar nanoparticles from glycosaminoglycans for CD44 targeted drug delivery
",
Biomacromolecules
, vol. 19, issue 7, pp. 2991 - 2999, doi:
10.1021/acs.biomac.8b00561
, 2018.
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RepositoriUM
Novoa-Carballal R.
,
Carretero A. C.
,
Pacheco R.
,
Reis R. L.
, and
Pashkuleva I.
,
"
Star-like glycosaminoglycans with superior bioactivity assemble with proteins into microfibers
",
Chemistry: A European Journal
, vol. 24, pp. 14341 - 14345, doi:
10.1002/chem.201802243
, 2018.
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RepositoriUM
José V. A.
,
Ramos P.
,
Valcarcel J.
,
Antelo, Luis T.
,
Novoa-Carballal R.
,
Reis R. L.
, and
Pérez Martín R. I.
,
"
An integral and sustainable valorisation strategy of squid pen by-products
",
Journal Of Cleaner Production
, vol. 201, pp. 207-218, doi:
10.1016/j.jclepro.2018.07.316
, 2018.
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RepositoriUM
Brito A.
,
Abul-Haija Y. M.
,
Soares da Costa D.
,
Novoa-Carballal R.
,
Reis R. L.
,
Ulijn R. V.
,
Pires R. A.
, and
Pashkuleva I.
,
"
Co-assembly of peptide and carbohydrate amphiphiles to generate proteoglycan mimics
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ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
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Fontelo R.
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