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2008 (148)
Lima H.
,
Araujo J. V.
,
Neves N. M.
,
Mano J. F.
, and
Reis R. L.
,
"
Cell encapsulation in thermoresponsive chitosan based hydrogels for cartilage tissue engineering
",
Tissue Engineering Part A
, vol. 14, issue 5, pp. 709-710, 2008.
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Cruz D. M. G.
,
Ivirico J. L. E.
,
Gomes M. E.
,
Ribelles J. L.
,
Sanchez M. S.
,
Reis R. L.
, and
Mano J. F.
,
"
Chitosan microparticles as injectable scaffolds for tissue engineering applications
",
Tissue Engineering Part A
, vol. 14, issue 5, pp. 821-821, 2008.
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Ribeiro C. A.
,
Salgado A. J.
,
Fraga J. S.
,
Neves N. M.
,
Gimble J. M.
,
Reis R. L.
, and
Sousa N.
,
"
A comparative study on the effects of adipose tissue derived and bone marrow mesenchymal stem cells on neurons/glial cells viability, proliferation and differentiation
",
Tissue Engineering Part A
, vol. 14, issue 5, pp. 800-801, 2008.
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Gomes S.
,
Rodrigues M. T.
,
Leonor I. B.
,
Gomes M. E.
,
Mano J. F.
, and
Reis R. L.
,
"
Conversion of corallina officinalis into calcium phosphates by using hydrothermal treatment and their potential for bone tissue engineering application
",
Tissue Engineering Part A
, vol. 14, issue 5, pp. 831-831, 2008.
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RepositoriUM
Gomes M. E.
,
Reis R. L.
,
Cunha A. M.
,
van Blitterswijk C. A.
, and
deBruijn J. D.
,
"
Cytocompatibility and response of osteoblastic-like cells to starch-based polymers: effect of several additives and processing conditions
",
Biomaterials
, vol. 22, issue 13, pp. 1911-1917, 2008.
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Ylikauppila H.
,
Nikkola L.
,
Tukiainen M.
,
Gomes M. E.
,
Reis R. L.
,
Kellomäki M.
, and
Ashammakhi N.
,
"
Development of bioactive glass fiber reinforced starch-polycaprolactone composite
",
Cytotherapy
, vol. 8, pp. 44-44, 2008.
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Caridade S. G.
,
da Silva R. M. P.
,
Reis R. L.
, and
Mano J. F.
,
"
Effect of solvent-dependent viscoelastic properties of chitosan membranes on the permeation of low molecular weight drugs
",
Tissue Engineering Part A
, vol. 14, issue 5, pp. 842-842, 2008.
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RepositoriUM
Bessa P. C.
,
Cerqueira M. T.
,
Rada T.
,
Gomes M. E.
,
Neves N. M.
,
Casal M.
, and
Reis R. L.
,
"
Expression, purification and bioactivity of recombinant human bone morphogenetic protein-4,-9,-10,-11 and-14 produced in Escherichia coli for tissue engineering applications
",
Tissue Engineering Part A
, vol. 14, issue 5, pp. 852-852, 2008.
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Pavlov M. P.
,
Mano J. F.
,
Neves N. M.
, and
Reis R. L.
,
"
Fibers and 3D mesh scaffolds from biodegradable starch-based blends: Production and characterization
",
Macromolecular Bioscience
, vol. 4, issue 8, pp. 776-784, 2008.
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Salgado A. J.
,
Fraga J. S.
,
Neves N. M.
,
Reis R. L.
, and
Sousa N.
,
"
Human umbilical cord perivascular cells (HUCPVCs) as source of mesenchymal progenitors for central nervous system regenerative medicine: Role of paracrine factors and direct cell-to-cell contacts in neurons/glial cells viability, proliferation and differe
",
Tissue Engineering
, vol. 13, issue 7, pp. 1707-1707, 2008.
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Oliveira J. M.
,
Kotobuki N.
,
Hirose M.
,
Mano J. F.
,
Reis R. L.
, and
Ohgushi H.
,
"
Intracellular carboxymethylchitosan/poly(amidoamine) nanocarriers loaded with dexamethasone enhances osteogenic differentiation of RBMSCs in vitro
",
Tissue Engineering
, vol. 13, issue 7, pp. 1719-1719, doi:
10.1089/ten.2007.1501
, 2008.
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Rada T.
,
Gomes M. E.
,
Neves N. M.
, and
Reis R. L.
,
"
Isolation of adipose stem cells (ASCs) subpopulations with distinct differentiation potential
",
Tissue Engineering Part A
, vol. 14, issue 5, pp. 751-751, 2008.
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Tuzlakoglu K.
,
Bolgen N.
,
Salgado A. J.
,
Gomes M. E.
,
Piskin E.
, and
Reis R. L.
,
"
Nano- and micro-fiber combined scaffolds: A new architecture for bone tissue engineering
",
Journal of Materials Science-Materials in Medicine
, vol. 16, issue 12, pp. 1099-1104, 2008.
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Salgado A. J.
,
Sousa R. A.
,
Oliveira J. T.
,
Silva N. A.
,
Neves N. M.
,
Reis R. L.
, and
Sousa N.
,
"
Novel tissue engineering 3D scaffolds for spinal cord injury based on starch/polycaprolactone blends: Development and preliminary assessment of their biological performance
",
Tissue Engineering
, vol. 13, issue 7, pp. 1736-1737, 2008.
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Rodrigues M. T.
,
Leonor I. B.
,
Viegas C. A. A.
,
Dias I. R.
,
Gomes M. E.
, and
Reis R. L.
,
"
Osteoconductive scaffolds obtained by means of in situ surface functionalization of wet-spun fibre meshes for bone regeneration applications
",
Tissue Engineering Part A
, vol. 14, issue 5, pp. 765-765, 2008.
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RepositoriUM
Silva S. S.
,
Oliveira J. M.
,
Mano J. F.
, and
Reis R. L.
,
"
Physicochemical characterization of novel chitosan-soy protein/TEOS porous hybrids for tissue engineering applications
",
Advanced Materials Forum Iii, Pts 1 and 2
, pp. 1000-1004, 2008.
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Salgado A. J.
,
Gomes M. E.
,
Chou A. M.
,
Coutinho O. P.
,
Reis R. L.
, and
Hutmacher D. W.
,
"
Preliminary study on the adhesion and proliferation of human osteoblasts on starch-based scaffolds
",
Materials Science & Engineering C-Biomimetic and Supramolecular Systems
, vol. 20, issue 1-2, pp. 27-33, 2008.
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Correlo V. M.
,
Boesel L. F.
,
Bhattacharya M.
,
Mano J. F.
,
Neves N. M.
, and
Reis R. L.
,
"
Properties of melt processed chitosan and aliphatic polyester blends
",
Materials Science and Engineering a-Structural Materials Properties Microstructure and Processing
, vol. 403, issue 1-2, pp. 57-68, 2008.
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Haltpeter
,
Bevis M. J.
,
Gomes M. E.
,
Cunha A. M.
, and
Reis R. L.
,
"
Shear controlled orientation in injection moulding of starch based blends intended for medical applications
",
Plastics Rubber and Composites
, vol. 32, issue 4, pp. 173-181, 2008.
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Silva N. A.
,
Salgado A. J.
,
Sousa R. A.
,
Oliveira J. T.
,
Neves N. M.
,
Mano J. F.
,
Sousa N.
, and
Reis R. L.
,
"
Starch/gellan gum hybrid 3D guidance systems for spinal cord injury regeneration: Scaffolds processing, characterization and biological evaluation
",
Tissue Engineering Part A
, vol. 14, issue 5, pp. 779-779, 2008.
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Gomes M. E.
,
Azevedo H. S.
,
Moreira A. R.
,
Ella V.
,
Kellomäki M.
, and
Reis R. L.
,
"
Starch-poly(epsilon-caprolactone) and starch-poly(lactic acid) fibre-mesh scaffolds for bone tissue engineering applications: structure, mechanical properties and degradation behaviour
",
Journal of Tissue Engineering and Regenerative Medicine
, vol. 2, issue 5, pp. 243-252, 2008.
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Ella V.
,
Gomes M. E.
,
Reis R. L.
,
Törmälä P.
, and
Kellomäki M.
,
"
Studies of P(L/D)LA 96/4 non-woven scaffolds and fibres; properties, wettability and cell spreading before and after intrusive treatment methods
",
Journal of Materials Science-Materials in Medicine
, vol. 18, issue 6, pp. 1253-1261, 2008.
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Rodrigues M. T.
,
Gomes M. E.
,
Viegas C. A. A.
,
Azevedo J. T.
,
Dias I. R.
, and
Reis R. L.
,
"
Tissue-engineered constructs based on SPCL scaffolds cultured with goat marrow cells: functionality in femoral defects
",
Tissue Engineering
, vol. 13, issue 7, pp. 1713-1713, 2008.
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da Silva R. M. P.
,
Caridade S. G.
,
Roman J. S.
,
Mano J. F.
, and
Reis R. L.
,
"
Transport of small anionic and neutral solutes through chitosan membranes: Dependence on crosslinking and chelation of divalent cations
",
Tissue Engineering Part A
, vol. 14, issue 5, pp. 923-924, 2008.
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RepositoriUM
Leonor I. B.
,
Gomes S.
,
Bessa P. C.
,
Casal M.
,
Mano J. F.
, and
Reis R. L.
,
"
New biomineralization strategies on natural-based polymeric materials for bone tissue engineering approaches
",
Natural-based Polymers for Biomedical Applications
,
Woodhead Publishing Limited
,
Cambridge
, pp. 193-230, 2008.
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Reis R. L.
, and
Mano J. F.
,
"
Effect of solvent-dependent viscoelastic properties of chitosan membranes on the permeation of 2-phenylethanol
",
Carbohydrate Polymers
, doi:
10.1016/j.carbpol.2008.09.011
, 2008.
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da Silva R. M. P.
,
Mano J. F.
, and
Reis R. L.
,
"
Straightforward determination of the degree of N-acetylation of chitosan by means of first-derivative UV spectrophotometry
",
Macromolecular Chemistry & Physics
, vol. 209, issue 14, pp. 1463-1472, 2008.
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da Silva R. M. P.
,
Caridade S. G.
,
SanRamon J.
,
Mano J. F.
, and
Reis R. L.
,
"
Transport of small anionic and neutral solutes through chitosan membranes: Dependence on cross-linking and chelation of divalent cations
",
Biomacromolecules
, vol. 9, issue 8, pp. 2132-2138, 2008.
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Pereira H.
,
Reis R. L.
,
Silva S. P.
, and
Marques A. V.
,
"
Process of cork pre-expansion by submission to microwave radiation and resulting product thereof
",
WO2008115086 (A1); 2008-09-25
, 2008.
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Balmayor E. R.
,
Bessa P. C.
,
Tuzlakoglu K.
,
Azevedo H. S.
,
Casal M.
, and
Reis R. L.
,
"
Novel biodegradable polymeric microparticles for the localized delivery of differentiation agents in bone tissue engineering applications
",
Tissue Engineering Part A
, vol. 14, issue 5, pp. 762-763, 2008.
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Balmayor E. R.
,
Tuzlakoglu K.
,
Marques A. P.
,
Azevedo H. S.
, and
Reis R. L.
,
"
A novel enzymatically-mediated drug delivery carrier for bone tissue engineering applications: combining biodegradable starch-based microparticles and differentiation agents
",
Journal of Materials Science-Materials in Medicine
, vol. 19, issue 4, pp. 1617-1623, 2008.
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Bessa P. C.
,
Balmayor E. R.
,
Cerqueira M. T.
,
Rada T.
,
Gomes M. E.
,
Neves N. M.
,
Azevedo H. S.
,
Casal M.
, and
Reis R. L.
,
"
Silk nanoparticles for delivery of human BMP-2 in bone regenerative medicine applications
",
Tissue Engineering Part A
, vol. 14, issue 5, pp. 776-777, 2008.
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Alves N. M.
, and
Mano J. F.
,
"
Chitosan derivatives obtained by chemical modifications for biomedical and environmental applications
",
International Journal of Biological Macromolecules
, vol. 43, pp. .401-414, 2008.
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Shi J.
,
Alves N. M.
, and
Mano J. F.
,
"
Chitosan-alginate Multilayer Beads Containing Poly(N-isopropylacrylamide) for Dual-Stimuli-Responsive Drug Release
",
J Biom Mat Res B
, vol. 84B, pp. 595-603, 2008.
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Santos J. R.
,
Alves N. M.
, and
Mano J. F.
,
"
New thermo-responsive hydrogels based on Hyaluronic acid/ poly(N-isopropylacrylamide) semi-interpenetrated polymer networks: swelling properties and drug release studies
",
Tissue Engineering: Part A
, vol. 14, pp. 886, 2008.
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Dias C. I.
,
Mano J. F.
, and
Alves N. M.
,
"
pH responsive biomineralization onto chitosan grafted biodegradable substrates
",
J. Mater. Chem.
, vol. 2493–2499, pp. 2493–2499, 2008.
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Santo V. E.
,
Prieto S.
,
Testera A. M.
,
Alonso M.
,
Arias F. J.
,
Mano J. F.
, and
Rodríguez-Cabello J. C.
,
"
Physical Properties of an Artificial Extracellular Matrix Based on a Crosslinked Elastin-like Polymer
",
Materials Science Forum
, vol. 587-588, pp. 47-51, 2008.
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Benesch J.
,
Mano J. F.
, and
Reis R. L.
,
"
Proteins and their peptide motifs in acellular apatite mineralisation of scaffolds for tissue engineering
",
Tissue Engineering B Reviews
, vol. 14, issue 4, pp. 433-445, 2008.
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Alves N. M.
,
Dias C. I.
, and
Mano J. F.
,
"
Stimuli-responsive biomineralization onto biodegradable substrates
",
Tissue Engineering: Part A
, vol. 14, pp. 780-781, 2008.
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Shi J.
,
Alves N. M.
, and
Mano J. F.
,
"
Towards bioinspired superhydrophobic poly(L-lactic acid) surfaces using phase inversion - based methods
",
Bioinspiration & Biomimetics
, vol. 3, pp. 034003, 2008.
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Bessa P. C.
,
Casal M.
, and
Reis R. L.
,
"
Bone morphogenetic proteins in tissue engineering: the road from laboratory to the clinic, part II, BMP delivery
",
Journal of Tissue Engineering and Regenerative Medicine
, vol. 2, pp. 81-96, 2008.
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Bessa P. C.
,
Casal M.
, and
Reis R. L.
,
"
Bone morphogenetic proteins in tissue engineering: the road from laboratory to the clinic, part I, basic concepts
",
Journal of Tissue Engineering and Regenerative Medicine
, vol. 2, pp. 1-13, 2008.
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Silva S. S.
,
Rodrigues M. T.
,
Motta A.
,
Gomes M. E.
,
Mano J. F.
,
Migliaresi C.
, and
Reis R. L.
,
"
Novel Genipin Cross-linked Chitosan-Silk based Sponges for the Regeneration and Repair of Cartilage using a Tissue Engineering Approach
",
Tissue Engineering: Part A
, vol. 14, issue 5, pp. 763, 2008.
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RepositoriUM
Gomes M. E.
,
Reis R. L.
, and
Gardel L.
,
"
Bi-directional continuous perfusion bioreactor for tridimensional culture op mammal tissue substitutes
",
PT104278 (A) 2010-06-04
, 2008.
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Oliveira J. M.
,
Sousa R. A.
,
Kotobuki N.
,
Tadokoro M.
,
Hirose M.
,
Mano J. F.
,
Reis R. L.
, and
Ohgushi H.
,
"
The Osteogenic Differentiation of Rat Bone Marrow Stromal Cells Cultured With Dexamethasone-loaded Carboxymethylchitosan/Poly(amidoamine) Dendrimer Nanoparticles
",
Biomaterials
, vol. 30, issue 5, pp. 804-813, 2008.
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Mrugala D.
,
Bony C.
,
Neves N. M.
,
Caillot L.
,
Fabre S.
,
Moukoko D.
,
Jorgensen C.
, and
Noel D.
,
"
Phenotypic and functional characterisation of ovine mesenchymal stem cells: application to a cartilage defect model
",
Annals of the Rheumatic Diseases
, vol. 67, issue 3, pp. 288-295, 2008.
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da Silva R. M. P.
,
Lopez-Perez P. M.
,
Elvira C.
,
Mano J. F.
,
SanRoman J.
, and
Reis R. L.
,
"
Poly(N-isopropylacrylamide) surface grafted chitosan membranes as a new substrate for cell sheet engineering and manipulation
",
Biotechnology and Bioengineering
, vol. 101, issue 6, pp. 1321-1331, 2008.
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Balmayor E. R.
,
Tuzlakoglu K.
,
Marques A. P.
,
Azevedo H. S.
, and
Reis R. L.
,
"
A Novel Enzymatically-Mediated Drug Delivery Carrier for Bone Tissue Engineering Applications: Combining Biodegradable Starch-based Microparticles and Differentiation Agents
",
Journal of Materials Science: Materials in Medicine.
, vol. 19/4, pp. 1617-1623, 2008.
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Neves N. M.
,
"
Biomaterial Scaffolds for Tissue Engineering
",
6th Marie Curie Cutting Edge Conference on Biocompatibility evaluation and biological behaviour of polymeric biomaterials
, 2008.
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Neves N. M.
,
"
Biomaterials and Adult Stem Cells in the Regeneration of Disease Damaged Tissues
",
XIV Portuguese Congress of Rheumatology
, 2008.
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Neves N. M.
,
"
New horizons on biomaterials and scaffolds for tissue engineering
",
International Conference BIOMED 2008
, 2008.
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Neves N. M.
,
"
Processing of chitosan-based scaffolds for bone tissue engineering
",
15th CIRMIB BIOMATERIALS SCHOOL and EXPERTISSUES SCHOOL & WORKSHOP on Strategies and Materials for REGENERATIVE MEDICINE: Focus on Bone and Cartilage
, 2008.
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Santo V. E.
,
Gomes M. E.
,
Mano J. F.
, and
Reis R. L.
,
"
Development of nanoparticles for bone tissue engineering applications
",
IV Meeting of Biomedical Engineering at University of Minho, Braga, Portugal
, 2008.
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Azevedo H. S.
,
Stupp S. I.
, and
Reis R. L.
,
"
Development of Self-Assembling Matrices Combining Hyaluronic Acid and Peptide Amphiphiles for Applications in Regenerative Medicine
",
42th Month Meeting of EXPERTISSUES NoE
, 2008.
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Pashkuleva I.
,
Azevedo H. S.
, and
Reis R. L.
,
"
Surface Structural Investigation of Starch-Based Biomaterials
",
Macromolecular Bioscience
, vol. 8, issue 2, pp. 210-219, 2008.
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Couto D. S.
,
Alves N. M.
, and
Mano J. F.
,
"
Multilayer coatings combining chitosan with bioactive glass nanoparticles
",
Journal of Nanoscience and Nanotechnology
, vol. 8, pp. 1-8, 2008.
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2009 (69)
Bessa P. C.
,
Cerqueira M. T.
,
Rada T.
,
Gomes M. E.
,
Neves N. M.
,
Nobre A.
,
Reis R. L.
, and
Casal M.
,
"
Expression, purification and osteogenic bioactivity of recombinant human BMP-4, -9, -10, -11 and -14
",
Protein Expression and Purification
, vol. 63, pp. 89-94, 2009.
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Malafaya P. B.
, and
Reis R. L.
,
"
Bilayered chitosan-based scaffolds for osteochondral tissue engineering: influence of hydroxylapatite on in vitro cytotoxicity and dynamic bioactivity studies in a specific double chamber bioreactor
",
Acta Biomaterialia
, vol. 5, issue 2, pp. 644-660, 2009.
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Caridade S. G.
,
da Silva R. M. P.
,
Reis R. L.
, and
Mano J. F.
,
"
Effect of Solvent-Dependent Viscoelastic Properties of Chitosan Membranes on the Permeation of 2-Phenylethanol
",
Carbohydrate Polymers
, vol. 75, issue 4, pp. 651-659, doi:
10.1016/j.carbpol.2008.09.011
, 2009.
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Correlo V. M.
,
Sol P. C.
,
Novikoff S.
,
Neves N. M.
, and
Reis R. L.
,
"
Novel PHB/PCL Scaffolds Produced by Melt Base Technologies
",
Tissue Engineering: Part A
, vol. 14, pp. 890, 2009.
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Duarte A. R. C.
,
Mano J. F.
, and
Reis R. L.
,
"
Preparation of chitosan scaffolds loaded with dexamethasone for tissue engineering applications using supercritical fluid technology
",
European Polymer Journal
, vol. 45, pp. 141-148, 2009.
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Martins A. M.
,
Pham Q. P.
,
Malafaya P. B.
,
Sousa R. A.
,
Gomes M. E.
,
Raphael R. M.
,
Kasper F. K.
,
Reis R. L.
, and
Mikos A. G.
,
"
The role of lipase and alpha-amylase in both the degradation of starch/poly(epsilon-caprolactone) fiber meshes and the osteogenic differentiation of cultured marrow stromal cells
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