Chitosan microparticles as injectable scaffolds for tissue engineering applications

last updated: 2017-03-07
TitleChitosan microparticles as injectable scaffolds for tissue engineering applications
Publication TypePapers in Scientific Journals
Year of Publication2008
AuthorsCruz D. M. G., Ivirico J. L. E., Gomes M. E., Ribelles J. L., Sanchez M. S., Reis R. L., and Mano J. F.
Abstract

The use of chitosan microparticles as injectable carriers for cell transplantation represents a
promising alternative to avoid the drawbacks of the implantation of other forms of three-dimensional
(3D) scaffolds seeded with cells. In this study, a 3D construct is obtained in vitro by combining
chitosan microparticles crosslinked with genipin and goat bone marrow stromal cells (GBMCs). Cell
viability and the morphology of GBMCs were evaluated after culture for 7 and 14 days. Our results
show the feasibility of chitosan microparticles as potential injectable scaffolds for tissue engineering
and regenerative medicine.
JournalTissue Engineering Part A
Volume14
Issue5
Pagination821-821
Date Published2008-11-05
Keywordschitosan microparticles, injectable scaffolds, minimally invasive surgical procedures, Stem cells, Tissue engineering
RightsopenAccess
Peer reviewedno
Statuspublished

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