Osteoconductive scaffolds obtained by means of in situ surface functionalization of wet-spun fibre meshes for bone regeneration applications
last updated: 2013-02-25
| Title | Osteoconductive scaffolds obtained by means of in situ surface functionalization of wet-spun fibre meshes for bone regeneration applications |
| Publication Type | Conference Abstract -ISI Web of Science Indexed |
| Year of Publication | 2008 |
| Authors | Rodrigues M. T., Leonor I. B., Viegas C. A. A., Dias I. R., Gomes M. E., and Reis R. L. |
| Abstract | The success of bone tissue engineering (TE) strategies is strongly dependent on the development of new synthetic materials com- bining osteoconductive, osteoinductive and osteogenic properties. Recent studies suggest that biomaterials incorporating silanol groups promote and maintain osteogenesis with or without bio- logical stimuli. This study aims to evaluate the osteoconductivity and osteogenic properties of novel wet-spun fibre mesh scaffolds of SPCL (blend of starch with polycaprolactone) with or without superficial functionalized silanol (Si-OH) groups by seeding/culturing them with goat marrow stromal cells (GBMCs) |
| Journal | Tissue Engineering Part A |
| Volume | 14 |
| Issue | 5 |
| Pagination | 765-765 |
| Date Published | 2008-11-05 |
| Keywords | Goat marrow stromal cells, Osteoconductive materials, silanol groups, starch-based polymers |
| Rights | restrictedAccess |
| Peer reviewed | yes |
| Status | published |
