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2004
Mano J. F.
,
Sousa N.
,
Boesel L. F.
,
Neves N. M.
, and
Reis R. L.
,
"
Bioinert, biodegradable and injectable polymeric matrix composites for hard tissue replacement: state of the art and recent developments
",
Composites Science and Technology
, vol. 64, pp. 789–817, 2004.
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2007
Salgado A. J.
,
Neves N. M.
,
Reis R. L.
, and
Sousa N.
,
"
Adult Stem Cells and Biomaterials in Central Nervous Regenerative Medicine
",
2nd Conference in Biotechnology
, 2007.
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Salgado A. J.
,
Silva N. A.
,
Neves N. M.
,
Reis R. L.
, and
Sousa N.
,
"
Hydrogel Based Systems for Spinal Cord Injury Regeneration
",
Handbook of Natural-based Polymers for Biomedical Applications
,
Reis RL
,
Cambridge
, pp. in press, 2007.
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2008
Salgado A. J.
,
Fraga J. S.
,
Neves N. M.
,
Reis R. L.
, and
Sousa N.
,
"
Role of paracrine factors released by mesenchymal progenitors from the umbilical cord in neurons/glial cell viability, proliferation and differentiation
",
Tissue Engineering Part A
, vol. 14, issue 5, pp. 695-695, 2008.
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Ribeiro C. A.
,
Salgado A. J.
,
Fraga J. S.
,
Neves N. M.
,
Gimble J. M.
,
Reis R. L.
, and
Sousa N.
,
"
A comparative study on the effects of adipose tissue derived and bone marrow mesenchymal stem cells on neurons/glial cells viability, proliferation and differentiation
",
Tissue Engineering Part A
, vol. 14, issue 5, pp. 800-801, 2008.
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Salgado A. J.
,
Fraga J. S.
,
Neves N. M.
,
Reis R. L.
, and
Sousa N.
,
"
Human umbilical cord perivascular cells (HUCPVCs) as source of mesenchymal progenitors for central nervous system regenerative medicine: Role of paracrine factors and direct cell-to-cell contacts in neurons/glial cells viability, proliferation and differe
",
Tissue Engineering
, vol. 13, issue 7, pp. 1707-1707, 2008.
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Salgado A. J.
,
Sousa R. A.
,
Oliveira J. T.
,
Silva N. A.
,
Neves N. M.
,
Reis R. L.
, and
Sousa N.
,
"
Novel tissue engineering 3D scaffolds for spinal cord injury based on starch/polycaprolactone blends: Development and preliminary assessment of their biological performance
",
Tissue Engineering
, vol. 13, issue 7, pp. 1736-1737, 2008.
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Silva N. A.
,
Salgado A. J.
,
Sousa R. A.
,
Oliveira J. T.
,
Neves N. M.
,
Mano J. F.
,
Sousa N.
, and
Reis R. L.
,
"
Starch/gellan gum hybrid 3D guidance systems for spinal cord injury regeneration: Scaffolds processing, characterization and biological evaluation
",
Tissue Engineering Part A
, vol. 14, issue 5, pp. 779-779, 2008.
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2009
Salgado A. J.
,
Sousa R. A.
,
Fraga J. S.
,
Pego J. M.
,
Silva B. A.
,
Malva J. O.
,
Neves N. M.
,
Reis R. L.
, and
Sousa N.
,
"
Effects of Starch/ Polycaprolactone-based Blends for Spinal Cord Injury Regeneration in Neurons/Glial Cells Viability and Proliferation
",
Journal of Bioactive and Biocompatible Polymers
, vol. 24, pp. 235-247, 2009.
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Pereira V. H.
,
Cerqueira S. R.
,
Fraga J. S.
,
Oliveira J. M.
,
Mano J. F.
,
Salgado A. J.
,
Reis R. L.
, and
Sousa N.
,
"
Dose dependent effects of FITC-labeled CMC/PAMAM dendrimer nanoparticles on central nervous system derived cells: In vitro and in vivo evaluation
",
Tissue Engineering and Regenerative Medicine
, vol. 6, issue 12, pp. S119, 2009.
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Cerqueira S. R.
,
Oliveira J. M.
,
Mano J. F.
,
Sousa N.
,
Salgado A. J.
, and
Reis R. L.
,
"
Cell targeted nano-based drug delivery systems for spinal cord injury regeneration
",
Tissue Engineering and Regenerative Medicine
, vol. 6, issue 12, pp. S82, 2009.
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2010
Oliveira J. M.
,
Salgado A. J.
,
Pirraco R. P.
,
Pereira V. H.
,
Fraga J. S.
,
Marques A. P.
,
Neves N. M.
,
Mano J. F.
,
Sousa N.
, and
Reis R. L.
,
"
In Vitro Characterization on the Interactions Between Carboxymethyl-chitosan/Poly(amidoamine) Dendrimer Nanoparticles and Neurons/Glial Cells
",
Tissue Engineering: Part A
, vol. 14, pp. 744, 2010.
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Silva N. A.
,
Salgado A. J.
,
Sousa R. A.
,
Oliveira J. T.
,
Pedro A. J.
,
Leite-Almeida H.
,
Cerqueira R.
,
Almeida A.
,
Mastronardi F.
,
Mano J. F.
,
Neves N. M.
,
Sousa N.
, and
Reis R. L.
,
"
Development and characterization of a novel hybrid tissue engineering-based scaffold for spinal cord injury repair
",
Tissue Engineering Part A
, vol. 16, issue 1, pp. 45-54, 2010.
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Salgado A. J.
,
Fraga J. S.
,
Mesquita A. R.
,
Neves N. M.
,
Reis R. L.
, and
Sousa N.
,
"
Role of human cord mesenchymal progenitors conditioned media in neuronal/glial cell densities, viability, and proliferation
",
Stem Cells And Development
, doi:
10.1089/scd.2009.0279.
, 2010.
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Ribeiro C. A.
,
Salgado A. J.
,
Fraga J. S.
,
Silva N. A.
,
Reis R. L.
, and
Sousa N.
,
"
The Secretome of Bone Marrow Mesenchymal Stem Cells Conditioned Media Varies with Time and Drives a Distinct Effect on Mature Neurons and Glial Cells(Primary Cultures)
",
Journal of Tissue Engineering and Regenerative Medicine
, 2010.
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Oliveira J. M.
,
Cerqueira S. R.
,
Salgado A. J.
,
Sousa N.
,
Mano J. F.
, and
Reis R. L.
,
"
Dendrimeric nanocarriers for intracellular cell- and tissue-engineering applications
",
2nd IBB Meeting, University of Minho
, 2010.
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2011
Salgado A. J.
,
Oliveira J. M.
,
Pirraco R. P.
,
Pereira V. H.
,
Fraga J. S.
,
Marques A. P.
,
Neves N. M.
,
Mano J. F.
,
Reis R. L.
, and
Sousa N.
,
"
Carboxymethyl-chitosan/Poly(amidoamine) Dendrimer Nanoparticles in Central Nervous System Regenerative Medicine: Effects on Neurons/Glial Cells Viability and Internalization efficiency
",
Macromolecular Bioscience
, vol. 10, issue 10, pp. 1130-1140, 2011.
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Cerqueira S. R.
,
Oliveira J. M.
,
Mano J. F.
,
Sousa N.
,
Salgado A. J.
, and
Reis R. L.
,
"
Dendrimer-based nanoparticle delivery system for the sustained and intracellular delivery of methylprednisolone to CNS cells: potential application in spinal cord injury treatment
",
Histology and Histopathology
, vol. 26, issue supplement1, pp. 323-324, 2011.
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Cerqueira S. R.
,
Silva B. L.
,
Oliveira J. M.
,
Mano J. F.
,
Sousa N.
,
Salgado A. J.
, and
Reis R. L.
,
"
Multifunctionalized CMCht/PAMAM Dendrimer Nanoparticles Modulate theCellular Uptake by Astrocytes and Oligodendrocytes in Primary Cultures of Glial Cells
",
Macromolecular Bioscience
, vol. 12, pp. 591–597, doi:
10.1002/mabi.201100294
, 2011.
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Pereira D. R.
,
Silva-Correia J.
,
Caridade S. G.
,
Oliveira J. T.
,
Sousa R. A.
,
Salgado A. J.
,
Oliveira J. M.
,
Mano J. F.
,
Sousa N.
, and
Reis R. L.
,
"
Development of Gellan-Gum based Microparticles/Hydrogel Matrices for Application in the Intervertebral Disc Regeneration
",
Tissue Engineering Part C: Methods
, vol. 17, issue 10, pp. 961-972, doi:
10.1089/ten.TEC.2011.0115
, 2011.
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Cerqueira S. R.
,
Oliveira J. M.
,
Mano J. F.
,
Salgado A. J.
,
Sousa N.
, and
Reis R. L.
,
"
Intracellular Methylprednisolone Release to Glial Cells Using An Engineered Dendrimer Nanoparticle System
",
The International Journal of Artificial Organs
, vol. 34, issue 8, pp. 639, 2011.
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Pereira V. H.
,
Salgado A. J.
,
Oliveira J. M.
,
Cerqueira S. R.
,
Frias A. M.
,
Fraga J. S.
,
Roque S.
,
Falcão A. M.
,
Marques F. M.
,
Neves N. M.
,
Mano J. F.
,
Reis R. L.
, and
Sousa N.
,
"
In Vivo Biodistribution of Carboxymethylchitosan/Poly(amidoamine) Dendrimer Nanoparticles in Rats
",
Journal of Bioactive and Compatible Polymers
, vol. 26, issue 6, pp. 619–627, 2011.
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Silva N. A.
,
Sousa R. A.
,
Pires A. O.
,
Sousa N.
,
Salgado A. J.
, and
Reis R. L.
,
"
Interactions Between Schwann and Olfactory Ensheathing Cells with a Starch/Polycaprolactone Scaffold aimed at Spinal Cord Injury Repair
",
Journal of Biomedical Materials Research Part A
, vol. 100A, issue 2, pp. 470-476, 2011.
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2012
Oliveira J. M.
,
Salgado A. J.
,
Sousa N.
,
Mano J. F.
, and
Reis R. L.
,
"
Dendrimers and Derivatives as a Potential Therapeutic Tool in Regenerative Medicine Strategies - A Review
",
Progress in Polymer Science
, vol. 35, issue 9, pp. 1163-1194, doi:
10.1016/j.progpolymsci.2010.04.006
, 2012.
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RepositoriUM
Silva-Correia J.
,
Miranda-Gonçalves V.
,
Salgado A. J.
,
Sousa N.
,
Oliveira J. M.
,
Reis R. M.
, and
Reis R. L.
,
"
Angiogenic potential of gellan gum-based hydrogels for application in nucleus pulposus regeneration: In vivo study
",
Tissue Engineering Part A
, vol. 18, issue 11-12, pp. 1203-1212, doi:
10.1089/ten.TEA.2011.0632
, 2012.
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RepositoriUM
Teixeira F. G.
,
Carvalho M. M.
,
Silva N. A.
,
Marques F.
,
Mesquita S. D.
,
Neves N. M.
,
Reis R. L.
,
Pinto L.
,
Sousa N.
, and
Salgado A. J.
,
"
Using the secretome of mesenchymal progenitors of the umbilical cord as a modulator of neural and glial survival, viability and differentiation
",
Journal of Tissue Engineering and Regenerative Medicine
, vol. 6, issue Suppl. 1, pp. 281-282, doi:
10.1002/term.1586
, 2012.
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RepositoriUM
Silva B. L.
,
Cerqueira S. R.
,
Fevereiro J. P.
,
Pirraco R. P.
,
Marques A. P.
,
Oliveira J. M.
,
Reis R. L.
,
Sousa N.
, and
Salgado A. J.
,
"
Hyaluronic acid/poly(amidoamine) dendrimer nanoparticles for central nervous system applications: In vitro and in vivo studies
",
Journal of Tissue Engineering and Regenerative Medicine
, vol. 6, issue Suppl.1, pp. 361-361, doi:
10.1002/term.1586
, 2012.
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RepositoriUM
Cerqueira S. R.
,
Pereira V. H.
,
Oliveira J. M.
,
Sousa N.
,
Salgado A. J.
, and
Reis R. L.
,
"
Biodistribution and preliminary therapeutic potential of CMCht/PAMAM dendrimer nanoparticles administration in rats
",
Journal of Tissue Engineering and Regenerative Medicine
, vol. 6, issue Suppl.1, pp. 88, doi:
10.1002/term.1586
, 2012.
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RepositoriUM
Cerqueira S. R.
,
Oliveira J. M.
,
Salgado A. J.
,
Sousa N.
, and
Reis R. L.
,
"
Nanoparticle-mediated drug delivery systems for spinal cord injury repair
",
Miami Project Lecture Series, The Miami Project To Cure Paralysis, Miller School of Medicine, University of Miami
, 2012.
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Cerqueira S. R.
,
Oliveira J. M.
,
Silva B. L.
,
Silva N. A.
,
Mano J. F.
,
Sousa N.
,
Salgado A. J.
, and
Reis R. L.
,
"
Intracellular delivery of methylprednisolone by dendrimer-based nanoparticles improves the locomotor outcomes after spinal cord injury
",
Journal of Tissue Engineering and Regenerative Medicine
, vol. 6, issue Suppl.2, pp. 19-19, doi:
10.1002/term.1608
, 2012.
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RepositoriUM
Oliveira A. L.
,
Sousa E. C.
,
Silva N. A.
,
Sousa N.
,
Salgado A. J.
, and
Reis R. L.
,
"
Peripheral mineralization of a 3D biodegradable tubularconstruct as a way to enhance guidance stabilization in spinal cord injury regeneration
",
Journal of Materials Science: Materials in Medicine
, doi:
10.1007/s10856-012-4741-0
, 2012.
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RepositoriUM
2013
Cerqueira S. R.
,
Oliveira J. M.
,
Silva N. A.
,
Leite-Almeida H.
,
Samy S. M.
,
Almeida A.
,
Mano J. F.
,
Sousa N.
,
Salgado A. J.
, and
Reis R. L.
,
"
Microglia response and in vivo therapeutic potential of methylprednisolone-loaded dendrimer nanoparticles in spinal cord injury
",
Small
, vol. 9, issue 5, pp. 738-749, 2013.
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RepositoriUM
Pojo M.
,
Cerqueira S. R.
,
Mota T.
,
Xavier-Magalhães A.
,
Oliveira J. M.
,
Samy S. M.
,
Mano J. F.
,
Reis R. L.
,
Costa B. M.
,
Sousa N.
, and
Salgado A. J.
,
"
In vitro evaluation of the cytotoxicity and cellular uptake of CMCht/PAMAM dendrimer nanoparticles by glioblastoma cell models
",
Journal of Nanoparticle Research (NANO)
, doi:
10.1007/s11051-013-1621-6
, 2013.
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RepositoriUM
Silva N. A.
,
Gimble J. M.
,
Sousa N.
,
Reis R. L.
, and
Salgado A. J.
,
"
Modulation of Bone Marrow Mesenchymal Stem Cell Secretome by ECM-Like Hydrogels.
",
STEM CELLS AND DEVELOPMENT olume 22, Number 8, 2013
, vol. 22, issue 8, pp. 1232-1240, doi:
doi: 10.1089/scd.2012.0524
, 2013.
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Cerqueira S. R.
,
Oliveira J. M.
,
Mano J. F.
,
Sousa N.
,
Salgado A. J.
, and
Reis R. L.
,
"
Regeneration Strategies in the Central Nervous System
",
3rd 3B´s Symposium on Biomaterials and Stem cells in Regenerative Medicine
, 2013.
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RepositoriUM
Fraga J. S.
,
Silva N. A.
,
Lourenço A. S.
,
Gonçalves V.
,
Neves N. M.
,
Reis R. L.
,
Rodrigues A. J.
,
Manadas B.
,
Sousa N.
, and
Salgado A. J.
,
"
Unveiling the effects of the Secretome of Mesenchymal Progenitors from the Umbilical Cord in Different Neuronal Cell Populations
",
Biochemie
, vol. 95, issue 12, pp. 2297-2303, doi:
10.1016/j.biochi.2013.06.028
, 2013.
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RepositoriUM
Ribeiro-Samy S. M.
,
Silva N. A.
,
Correlo V. M.
,
Fraga J. S.
,
Pinto L. A.
,
Teixeira-Castro A.
,
Leite-Almeida H.
,
Almeida A.
,
Gimble J. M.
,
Sousa N.
,
Salgado A. J.
, and
Reis R. L.
,
"
Development and Characterization of a PHB-HV-based 3D Scaffold for a Tissue Engineering and Cell-therapy Combinatorial Approach for Spinal Cord Injury Regeneration
",
Macromolecular Bioscience
, doi:
10.1002/mabi.201300178
, 2013.
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RepositoriUM
Salgado A. J.
,
Oliveira J. M.
,
Martins A.
,
Teixeira F. G.
,
Silva N. A.
,
Neves N. M.
,
Sousa N.
, and
Reis R. L.
,
"
Tissue Engineering and Regenerative Medicine: Past, Present, and Future
",
Tissue Engineering of the Peripheral Nerve: Stem Cells and Regeneration Promoting FactorsAcademic Press
,
Eds.
Geuna S.
,
Perroteau I.
,
Tos P.
, and
Battiston B.
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Academic Press
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10.1016/B978-0-12-410499-0.00001-0
, 2013.
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Salgado A. J.
,
Oliveira J. M.
,
Matins A.
,
Teixeira F. G.
,
Silva N. A.
,
Neves N. M.
,
Reis R. L.
, and
Sousa N.
,
"
Tissue Engineering and Regenerative Medicine: Past, Present, and Future
",
Int Rev Neurobiol.
, vol. 108, pp. 11-33, 2013.
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RepositoriUM
2014
Cerqueira S. R.
,
Chowdhury H. H.
,
Mano J. F.
,
Oliveira J. M.
,
Sousa N.
,
Zorec R.
, and
Reis R. L.
,
"
Unveiling the intracellular trafficking of drug-loaded dendrimer nanoparticles in astrocytes
",
J Tissue Eng Regen Med
, vol. 8, issue 1, pp. 39-206, doi:
10.1002/term.1931
, 2014.
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RepositoriUM
2015
Canha-Gouveia A.
,
Costa-Pinto A. R.
,
Martins A.
,
Silva N. A.
,
Faria S.
,
Sousa R. A.
,
Salgado A. J.
,
Sousa N.
,
Reis R. L.
, and
Neves N. M.
,
"
Hierarchical scaffolds enhance osteogenic differentiation of human Wharton’s Jelly derived Stem Cells
",
Biofabrication
, vol. 7, issue 3, pp. 035009, doi:
10.1088/1758-5090/7/3/035009
, 2015.
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RepositoriUM
2017
Duarte A. R. C.
,
Maniglio D.
,
Sousa N.
,
Mano J. F.
,
Reis R. L.
, and
Migliaresi C.
,
"
From honeycomb- to microsphere-patterned surfaces of poly(lactic acid) and a starch-poly(lactic acid) blend via the breath figure method
",
Journal of Applied Biomaterials & Functional Materials
, vol. 15, issue 1, pp. e31-e42, doi:
10.5301/jabfm.5000281
, 2017.
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RepositoriUM
Cengiz I. F.
,
Pereira H.
,
Pego J. M.
,
Sousa N.
,
Espregueira-Mendes J.
,
Oliveira J. M.
, and
Reis R. L.
,
"
Segmental and regional quantification of 3D cellular density of human meniscus from osteoarthritic knee
",
Journal of Tissue Engineering and Regenerative Medicine
, vol. 11, pp. 1844-1852, doi:
10.1002/term.2082
, 2017.
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RepositoriUM
2018
Chowdury H. H.
,
Cerqueira S. R.
,
Sousa N.
,
Oliveira J. M.
,
Reis R. L.
, and
Zorec R.
,
"
The Uptake, Retention and Clearance of Drug-Loaded Dendrimer Nanoparticles in Astrocytes - Electrophysiological Quantification
",
Biomaterials Science
, vol. 6, issue 2, pp. 388-397, doi:
10.1039/C7BM00886D
, 2018.
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RepositoriUM
2020
Soares da Costa D.
,
Sousa J. C.
,
da Mesquita S.
,
Petkova-Yankova N.
,
Marques F.
,
Reis R. L.
,
Sousa N.
, and
Pashkuleva I.
,
"
Bioorthogonal Labeling Reveals Different Expression of Glycans in Mouse Hippocampal Neuron Cultures during Their Development
",
Molecules
, vol. 25, issue 4, pp. 795, doi:
10.3390/molecules25040795
, 2020.
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RepositoriUM
Publications
Papers in Scientific Journals
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Book Chapter
Invited Journal Paper
Invited Review Paper
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