| Title | Bioinert, biodegradable and injectable polymeric matrix composites for hard tissue replacement: state of the art and recent developments |
| Publication Type | Review Paper |
| Year of Publication | 2004 |
| Authors | Mano J. F., Sousa N., Boesel L. F., Neves N. M., and Reis R. L. |
| Abstract Text | The present review paper examines the use of different types of polymeric matrix composites in hard tissue replacement applica- tions.Thereviewpresentstheactualstateoftheartinthefieldsofbioinertcompositesforpermanentapplications,biodegradable matrixcompositesfortemporaryapplicationsandtheemergingareaofinjectablecomposites.Inallcasessomerecentdevelop- mentsarealsodiscussed.Thepaperstartswithanintroductiontolocatethereader.Bone–analoguecompositesarethenextensively discussed.Severalothersystemsbasedonaninertpolymericmatrixaredescribed,focusingontheirproposedapplications.Agreat emphasisisafterwardsgiventobiodegradablematrixsystems.Themostwidelyusedsyntheticbioresorbablesystemsareanalysed andcomparedwithanexampleofnaturalorigindegradablecomposites–starchbasedcomposites.Finally,compositesystemsthat are non-processable by melt based routes and in many cases injectable are discussed in detail, including several recent developments on this emerging area of research. |
| Journal | Composites Science and Technology |
| Volume | 64 |
| Pagination | 789–817 |
| Date Published | 2004-09-01 |
| Keywords | Biomaterials, Injection moulding, Mechanicalproperties, Microstructure, Polymer matrix composites |
| Rights | openAccess |
| Peer reviewed | yes |
| Status | published |