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Comunications - Poster
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Patent
2006
Rodrigues M. T.
,
Gomes M. E.
,
Viegas C. A. A.
,
Dias I. R.
,
Azevedo J. T.
, and
Reis R. L.
,
"
Establishing procedures for using a goat model for studying autologous tissue engineering strategies for the repair of cartilage and bone defects
",
30th Anual Meeting Society for Biomaterials (SFB)
, 2006.
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Rodrigues M. T.
,
Gomes M. E.
,
Viegas C. A. A.
,
Azevedo J. T.
,
Dias I. R.
, and
Reis R. L.
,
"
Novel hydroxyapatite/chitosan bilayer scaffolds for the regeneration of osteochondral defects using a tissue engineering approach based on culturing and differentiation of goat marrow cells into osteoblasts or chondrocytes
",
World Congress on Tissue Engineering and Regenerative Medicine
, 2006.
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Rodrigues M. T.
,
Oliveira J. M.
,
Gomes M. E.
,
Viegas C. A. A.
,
Azevedo J. T.
,
Dias I. R.
,
Mano J. F.
, and
Reis R. L.
,
"
Preliminary studies on single- and bilayered- hydroxyapatite/chitosan scaffolds seeded with osteoblasts or chondrocytes differentiated from goat marrow cells for the regeneration of bone and cartilage defects
",
1st Marie Curie Cutting Edge Conference
, 2006.
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Rodrigues M. T.
,
Gomes M. E.
,
Viegas C. A. A.
,
Azevedo J. T.
,
Dias I. R.
, and
Reis R. L.
,
"
Using a goat model for studying autologous tissue engineering strategies for the repair of cartilage and bone defects: optimization of harvesting and culturing methodologies
",
Sociedade Portuguesa de Células Estaminais e Terapia Celular (SPCE-TC)
, 2006.
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Rodrigues M. T.
,
Oliveira J. M.
,
Gomes M. E.
,
Viegas C. A. A.
,
Dias I. R.
,
Mano J. F.
, and
Reis R. L.
,
"
Novel hydroxyapatite/chitosan bilayer scaffolds for the regeneration of osteochondral defects using a tissue engineering approach based on culturing and differentiation of goat marrow cells into osteoblasts or chondrocytes
",
World Congress on Tissue Engineering and Regenerative Medicine
, 2006.
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Oliveira J. M.
,
Rodrigues M. T.
,
Silva S. S.
,
Malafaya P. B.
,
Gomes M. E.
,
Viegas C. A. A.
,
Azevedo J. T.
,
Dias I. R.
,
Mano J. F.
, and
Reis R. L.
,
"
Novel hydroxyapatite/chitosan bilayered scaffold for osteochondral tissue-engineering applications: scaffold design and its performance when seeded with goat bone marrow stromal cells
",
Biomaterials
, vol. 27, pp. 6123-6137, 2006.
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2007
Gomes M. E.
,
Rodrigues M. T.
,
Viegas C. A. A.
,
Azevedo J. T.
,
Dias I. R.
, and
Reis R. L.
,
"
In vivo functionality of autologous tissue engineered constructs based on SPCL scaffolds cultured with goat marrow cells
",
31st Annual Meeting Society for Biomaterials
, 2007.
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Rodrigues M. T.
,
Gomes M. E.
,
Viegas C. A. A.
,
Azevedo J. T.
,
Dias I. R.
, and
Reis R. L.
,
"
In vivo functionality of autologous tissue engineered constructs based on SPCL scaffolds cultured with goat marrow cells: implantation in non-critical femoral defects
",
31st Annual Meeting Society for Biomaterials (SFB 2007)
, 2007.
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Rodrigues M. T.
,
Leonor I. B.
,
Viegas C. A. A.
,
Dias I. R.
,
Gomes M. E.
, and
Reis R. L.
,
"
In Situ functionalization of 3D Wet-Spun fiber meshes for bone tissue engineering approaches using marrow stromal cells
",
1st Summer School of Termis-EU
, 2007.
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Rodrigues M. T.
,
Gomes M. E.
,
Viegas C. A. A.
,
Dias I. R.
,
Azevedo J. T.
,
Tamaño F.
, and
Reis R. L.
,
"
In vivo functionality of autologous tissue engineered constructs based on SPCL scaffolds cultured with goat marrow cells: implantation in non-critical femoral defects
",
TERMIS-EU 2007
, 2007.
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Gomes M. E.
,
Rodrigues M. T.
,
Viegas C. A. A.
,
Dias I. R.
,
Azevedo J. T.
, and
Reis R. L.
,
"
In vivo functionality of goat marrow cells seeded onto SPCL scaffolds constructs in induced non critical femoral defects
",
TERMIS-AP 2007
, 2007.
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Rodrigues M. T.
,
Leonor I. B.
,
Tuzlakoglu K.
,
Gomes M. E.
,
Viegas C. A. A.
,
Dias I. R.
, and
Reis R. L.
,
"
Novel In Situ Approach for the Design of Osteoconductive and Osteoinductive 3D Wet-Spun Fibre Mesh Scaffolds for Bone Tissue Engineering
",
TERMIS-AP
, 2007.
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Gomes M. E.
,
Oliveira J. T.
,
Rodrigues M. T.
,
Santos M. I.
,
Tuzlakoglu K.
,
Viegas C. A. A.
,
Dias I. R.
, and
Reis R. L.
,
"
Starch-polycaprolactone based scaffolds in bone and cartilage tissue engineering approaches
",
Natural-based polymers for biomedical applications
,
Eds.
Reis R. L.
,
Woodhead
,
Cambridge
, 2007.
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2008
Frias A. M.
,
Dias I. R.
,
Viegas C. A. A.
,
Fernandes S.
,
Barros A.
,
Azevedo J. T.
,
Neves N. M.
, and
Reis R. L.
,
"
In Vivo Engraftment Potential of human Bone Marrow and Amniotic Fluid Stem Cells Cultured under Osteogenic Conditions
",
TERMIS-EU 2008 Tissue Engineering International & Regenerative Medicine Society Meeting
, 2008.
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Rodrigues M. T.
,
Leonor I. B.
,
Viegas C. A. A.
,
Dias I. R.
,
Gomes M. E.
, and
Reis R. L.
,
"
Osteoconductive scaffolds obtained by means of in situ surface Functionalization of Wet-Spun Fibre Meshes for Bone Regeneration Applications
",
TERMIS-EU 2008
, 2008.
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Dias I. R.
,
Viegas C. A. A.
,
Azevedo J. T.
,
Costa E. M.
,
Lourenço P.
,
Rodrigues A.
, and
Cabrita A. S.
,
"
Assessment of bone formation markers under controlled environmental conditions and their correlations with serum minerals in the adult sheep as a model for orthopaedic research
",
Laboratory Animals
, vol. 42, issue 4, pp. 465-472, 2008.
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Rodrigues M. T.
,
Leonor I. B.
,
Viegas C. A. A.
,
Dias I. R.
,
Gomes M. E.
, and
Reis R. L.
,
"
Bioactive 3D Wet-Spun Fibre Meshes for Bone Regeneration obtained Using a Simple One-Step Methodology
",
6th Marie Curie Cutting Edge InVents Conference
, 2008.
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Rodrigues M. T.
,
Leonor I. B.
,
Viegas C. A. A.
,
Dias I. R.
,
Gomes M. E.
, and
Reis R. L.
,
"
Osteoconductive scaffolds obtained by means of in situ surface functionalization of wet-spun fibre meshes for bone regeneration applications
",
Tissue Engineering Part A
, vol. 14, issue 5, pp. 765-765, 2008.
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RepositoriUM
Rodrigues M. T.
,
Gomes M. E.
,
Viegas C. A. A.
,
Azevedo J. T.
,
Dias I. R.
, and
Reis R. L.
,
"
Tissue-engineered constructs based on SPCL scaffolds cultured with goat marrow cells: functionality in femoral defects
",
Tissue Engineering
, vol. 13, issue 7, pp. 1713-1713, 2008.
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2009
Rodrigues M. T.
,
Gomes M. E.
,
Viegas C. A. A.
,
Azevedo J. T.
,
Dias I. R.
, and
Reis R. L.
,
"
In vivo functionality of goat marrow cells seeded onto SPCL scaffolds constructs in induced femoral defects
",
Course on Preclinical Models and Imaging in Musculoskeletal Tissue Engineering
, 2009.
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Frias A. M.
,
Dias I. R.
,
Viegas C. A. A.
,
Fernandes S.
,
Barros A.
,
Azevedo J. T.
,
Neves N. M.
, and
Reis R. L.
,
"
Engraftment potential of human Amniotic Fluid and Bone Marrow Stem Cells cultured in expansion and osteogenic conditions in a Fetal Sheep Model
",
7th Annual Meeting of the International Society for Stem Cell Research (ISSCR)
, 2009.
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Carvalho P. P.
,
Santo V. E.
,
Rodrigues M. T.
,
Dias I. R.
,
Gomes M. E.
, and
Reis R. L.
,
"
Preliminary Study on the Osteogenic Behaviors of ASCs + Platelet Lysates Seeded onto SPCL Fiber Mesh Scaffolds
",
2nd Marie Curie Cutting Edge Practical Training Course Tissue engineering, stem cells and biocompatibility testing of biomaterials August 24 – September 3, 2009.
, 2009.
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2010
Dias I. R.
,
Viegas C. A. A.
,
Azevedo J. T.
,
Sousa C. P.
,
Ferreira A. J.
,
Cabrita A. S.
, and
Reis R. L.
,
"
Evaluation of biomarkers of bone formation and serum minerals variations for prediction of fracture healing versus non-union process in sheep as a model for orthopedic research
",
2010 World Veterinary Orthopaedic Congress
, 2010.
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Costa P. F.
,
Dias A. F.
,
Dias I. R.
,
Gomes M. E.
, and
Reis R. L.
,
"
Evaluation of the effect of cryopreservation over the functionality of bone-generating cell/tissue constructs
",
2nd Meeting of the Institute for Biotechnology and Bioengineering
, 2010.
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Carvalho P. P.
,
Yu G.
,
Wu X.
,
Dias I. R.
,
Gomes M. E.
,
Reis R. L.
, and
Gimble J. M.
,
"
Human Adipose-derived Stromal/Stem Cells: Use of Animal Free Products & Extended Storage at Room Temperature
",
iFATS
, 2010.
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Carvalho P. P.
,
Yu G.
,
Wu X.
,
Dias I. R.
,
Gomes M. E.
,
Reis R. L.
, and
Gimble J. M.
,
"
Processing and Passaging of Human Adipose-derived Stromal/Stem Cells (ASC): Use of Animal Free Products and Extended Storage at Room Temperature
",
Gordon Research Conference - Musculoskeletal Biology & Bioengineering
, 2010.
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Carvalho P. P.
,
Yu G.
,
Wu X.
,
Dias I. R.
,
Gomes M. E.
,
Reis R. L.
, and
Gimble J. M.
,
"
Processing and Passaging of Human Adipose-derived Stromal/Stem Cells (ASC): Use of Animal Free Products and Extended Storage at Room Temperature
",
SPCE-TC
, 2010.
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Frias A. M.
,
Dias I. R.
,
Viegas C. A. A.
,
Fernandes S.
,
Barros A.
,
Neves N. M.
, and
Reis R. L.
,
"
Human Amniotic Fluid and Bone Marrow Stem Cells engraftment potential after in vitro culturing in osteogenic media
",
5th Annual International Meeting of the Portuguese Society for Stem Cells and Cellular Therapies
, 2010.
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Dias I. R.
,
Viegas C. A. A.
,
Silva A. M.
,
Pereira H. F.
,
Sousa C. P.
,
Carvalho P. P.
,
Cabrita A. S.
,
Fonte P. J.
,
Silva S. R.
, and
Azevedo J. T.
,
"
Assessment of haematological and biochemical parameters in Portuguese Churra-da-Terra-Quente ewes of the northeast of Portugal
",
Brasilian Journal of Veterinary and Animal Sciences
, vol. 62, issue 2, pp. 265-272, 2010.
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2011
Rodrigues M. T.
,
Gomes M. E.
,
Viegas C. A. A.
,
Azevedo J. T.
,
Dias I. R.
,
Gúzon F. M.
, and
Reis R. L.
,
"
Tissue Engineered Constructs based on SPCL Scaffolds Cultured with Goat Marrow Cells: Functionality in Femoral Defects
",
Journal of Tissue Engineering and Regenerative Medicine
, vol. 5, pp. 41-49, 2011.
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Gonçalves A.
,
Costa P. F.
,
Rodrigues M. T.
,
Dias I. R.
,
Reis R. L.
, and
Gomes M. E.
,
"
Effect of flow perfusion conditions in the chondrogenic differentiation of bone marrow stromal cells cultured onto starch based biodegradable scaffolds
",
Acta Biomaterialia(doi:10.1016/j.actbio.2010.11.044)
, vol. 7, pp. 1644-1652, 2011.
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Carvalho P. P.
,
Wu X.
,
Yu G.
,
Dietrich M.
,
Dias I. R.
,
Gomes M. E.
,
Reis R. L.
, and
Gimble J. M.
,
"
Use of animal protein-free products for passaging adherent human adipose-derived stromal/stem cells.
",
Cytotherapy
, vol. 13, issue 5, pp. 594-7, 2011.
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Popa E. G.
,
Carvalho P. P.
,
Dias A. F.
,
Santo V. E.
,
Frias A. M.
,
Marques A. P.
,
Dias I. R.
,
Viegas C. A. A.
,
Gomes M. E.
, and
Reis R. L.
,
"
In vitro and in vivo biocompatibility evaluation of k-carrageenan hydrogels aimed at applications in regenerative medicine
",
HISTOLOGY AND HISTOPATHOLOGY Cellular and Molecular Biology
, vol. 26, issue supplement1, pp. 62, 2011.
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Carvalho P. P.
,
Yu G.
,
Wu X.
,
Dias I. R.
,
Gomes M. E.
,
Reis R. L.
, and
Gimble J. M.
,
"
Developing optimized methods for cGMP compliance in the isolation of human adipose-derived stromal/stem cells.
",
European Chapter of the Tissue Engineering and Regenerative Medicine International Society (TERMIS) 2011 Annual Meeting, Granada, Spain, June 2011
, 2011.
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Popa E. G.
,
Carvalho P. P.
,
Dias A. F.
,
Santo V. E.
,
Frias A. M.
,
Marques A. P.
,
Dias I. R.
,
Viegas C. A. A.
,
Gomes M. E.
, and
Reis R. L.
,
"
In vitro and in vivo biocompatibility evaluation of k-carrageenan hydrogels aimed at applications in regebnerative medicine
",
TERMIS-EU Annual Meeting
, 2011.
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Carvalho P. P.
,
Santo V. E.
,
Rodrigues M. T.
,
Dias I. R.
,
Gomes M. E.
, and
Reis R. L.
,
"
Platelet Lysates as a scaffold complement promoting hASCs proliferation and osteogenic differentiation
",
4th Joint ESAO-IFAO Congress 2011, Porto, Portugal, June 2011
, 2011.
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Carvalho P. P.
,
Santo V. E.
,
Rodrigues M. T.
,
Dias I. R.
,
Gomes M. E.
, and
Reis R. L.
,
"
Developing optimized methods for cGMP compliance in the isolation of human adipose-derived stromal/stem cells.
",
INTERNATIONAL JOURNAL OF ARTIFICIAL ORGANS
, vol. 34, issue 8, pp. 693-693, 2011.
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Carvalho P. P.
,
Yu G.
,
Wu X.
,
Dias I. R.
,
Gomes M. E.
,
Reis R. L.
, and
Gimble J. M.
,
"
Developing optimized methods for cGMP compliance in the isolation of human adipose-derived stromal/stem cells.
",
HISTOLOGY AND HISTOPATHOLOGY Cellular and Molecular Biology
, vol. 26, issue Supplement1, pp. 2, 2011.
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Carvalho P. P.
,
Wu X.
,
Yu G.
,
Dias I. R.
,
Gomes M. E.
,
Reis R. L.
, and
Gimble J. M.
,
"
The Effect of Storage Time on Adipose-Derived Stem Cell Recovery from Human Lipoaspirates
",
Cells Tissues Organs
, vol. 196, issue 4, pp. 494-500, 2011.
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2012
Rodrigues M. T.
,
Martins A.
,
Dias I. R.
,
Viegas C. A. A.
,
Neves N. M.
,
Gomes M. E.
, and
Reis R. L.
,
"
Synergistic effect of scaffold composition and dynamic culturing environment in multilayered systems for bone tissue engineering
",
Journal of Tissue Engineering and Regenerative Medicine (published online)
, 2012.
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Viegas C. A. A.
,
Requicha J. F.
,
Albuquerque C. M.
,
Sargo T.
,
Machado J.
,
Dias I. R.
,
Pires M. A.
,
Campino L.
, and
Cardoso L.
,
"
Tongue nodules in canine leishmaniosis - a case report
",
Parasites & Vectors
, vol. 5, issue 120, pp. 1-5, doi:
10.1186/1756-3305-5-120
, 2012.
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RepositoriUM
Carvalho P. P.
,
Dias I. R.
,
Gimble J. M.
,
Gomes M. E.
, and
Reis R. L.
,
"
Isolation of human adipose-derived stromal/stem cells using different grades of collagenase
",
7th International Meeting of the Portuguese Society for Stem Cells and Cell Therapies (SPCE-TC)
, 2012.
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Carvalho P. P.
,
Gimble J. M.
,
Dias I. R.
,
Gomes M. E.
, and
Reis R. L.
,
"
Translating human Adipose-derived Stem Cells (hASCs) to Clinical Practice requires standardization of isolation and culture protocols
",
TERM STEM
, 2012.
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RepositoriUM
2013
Bunnell B. A.
,
Gagliardi C.
, and
Dias I. R.
,
"
MSCs studies in large-animal models
",
Mesenchymal Stromal Cells: Biology and Clinical Applications
,
Springer
, pp. 237-258 , doi:
10.1007/978-1-4614-5711-4_13
, 2013.
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Carvalho P. P.
,
Gimble J. M.
,
Dias I. R.
,
Gomes M. E.
, and
Reis R. L.
,
"
Xeno-free enzymatic products for the isolation of human adipose-derived stromal/stem cells
",
Tissue Eng Part C Methods
, vol. 19, issue 6, pp. 473-478, doi:
10.1089/ten.tec.2012.0465
, 2013.
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Carvalho P. P.
,
Leonor I. B.
,
Smith B. J.
,
Dias I. R.
,
Reis R. L.
,
Gimble J. M.
, and
Gomes M. E.
,
"
Undifferentiated human adipose-derived stromal/stem cells loaded onto wet-spun starch-polycaprolactone scaffolds enhance bone regeneration: Nude mice calvarial defect in vivo study
",
Journal of Biomedical Materials and Research - Part A
, pp. [Epub ahead of print], doi:
DOI: 10.1002/jbm.a.34983
, 2013.
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Dias I. R.
,
Sousa C. P.
,
Carvalho P. P.
,
Lempeck M. R.
,
Viegas C. A.
, and
Azevedo J. T.
,
"
Bone grafts and substitutes in small animal orthopaedic reconstrutive surgery - A breaf review
",
Brazilian Journal of Veterinary Medicine
, vol. 35, issue 4, pp. 339-350, 2013.
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Sousa C. P.
,
Azevedo J. T.
,
Silva A. M.
,
Viegas C. A.
,
Reis R. L.
,
Gomes M. E.
, and
Dias I. R.
,
"
Serum total and bone alkaline phosphatase levels and their correlation with serum minerals over the lifespan of sheep. Acta Veterinaria Hungarica
",
Acta Veterinaria Hungarica
, vol. 62, issue 2, pp. 205-214, doi:
10.1556/AVet.2013.049
, 2013.
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Sousa C. P.
,
Azevedo J. T.
,
Silva A. M.
,
Viegas C. A.
,
Reis R. L.
,
Gomes M. E.
, and
Dias I. R.
,
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Serum total and bone alkaline phosphatase levels and their correlation with serum minerals over the lifespan of sheep.
",
Acta Vet Hung
, 2013.
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RepositoriUM
2014
Sousa C. P.
,
Azevedo J. T.
,
Reis R. L.
,
Gomes M. E.
, and
Dias I. R.
,
"
Short-term variability in biomarkers of bone metabolism in sheep.
",
Lab Animal
, vol. 43, issue 1, pp. 21-26, doi:
10.1038/laban.418
, 2014.
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Popa E. G.
,
Carvalho P. P.
,
Dias A. F.
,
Santos T. C.
,
Santo V. E.
,
Marques A. P.
,
Viegas C. A.
,
Dias I. R.
,
Gomes M. E.
, and
Reis R. L.
,
"
Evaluation of the in vitro and in vivo biocompatibility of carrageenan based hydrogels
",
Journal of Biomedical Materials Research part A
, doi:
10.1002/jbm.a.35081
, 2014.
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2015
Khang G.
,
Lee S. K.
,
Kim H. N.
,
Silva-Correia J.
,
Gomes M. E.
,
Viegas C. A. A.
,
Dias I. R.
,
Oliveira J. M.
, and
Reis R. L.
,
"
Biological evaluation of intervertebral disc cells in different formulations of gellan gum-based hydrogels
",
Journal of Tissue Engineering and Regenerative Medicine
, vol. 9, issue 3, pp. 265-275 , doi:
10.1002/term.1625
, 2015.
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Sousa C. P.
,
Dias I. R.
,
Lopez M.
,
Camassa J. A.
,
Lourenço P. J.
,
Judas F. M.
,
Gomes M. E.
, and
Reis R. L.
,
"
Bone turnover markers for early detection of fracture healing disturbances: A review of the scientific literature
",
Anais da Academia Brasileira de Ciências
, vol. 87, issue 2, pp. 1049-1061, 2015.
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2018
Dias I. R.
,
Camassa J. A.
,
Bordelo J. A.
,
Babo P. S.
,
Viegas C. A.
,
Dourado N.
,
Reis R. L.
, and
Gomes M. E.
,
"
Preclinical and Translational Studies in Small Ruminants (Sheep and Goat) as Models for Osteoporosis Research
",
Current Osteoporosis Reports
, vol. 16, issue 2, pp. 182-197, doi:
10.1007/s11914-018-0431-2
, 2018.
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Pereira D. R.
,
Canadas R. F.
,
Silva-Correia J.
,
da Silva Morais A.
,
Oliveira M. B.
,
Dias I. R.
,
Mano J. F.
,
Marques A. P.
,
Reis R. L.
, and
Oliveira J. M.
,
"
Injectable gellan-gum/hydroxyapatite-based bilayered hydrogel composites for osteochondral tissue regeneration
",
Applied Materials Today
, vol. 12, pp. 309-321, doi:
10.1016/j.apmt.2018.06.005
, 2018.
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2020
Coelho C. A.
,
BORDELO J. P.
,
Camassa J. A.
,
Barros V. A.
,
Babo P. S.
,
Gomes M. E.
,
Reis R. L.
,
Azevedo J. T.
,
Requicha J. F.
,
Faísca P.
,
Carvalho P. P.
,
Viegas C. A.
, and
Dias I. R.
,
"
Evaluation of hematology, general serum biochemistry, bone turnover markers and bone marrow cytology in a glucocorticoid treated ovariectomized sheep model for osteoporosis research
",
An Acad Bras Cienc
, vol. 92, issue 4, pp. 2-16, doi:
10.1590/0001-3765202020200435
, 2020.
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