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Papers in Scientific Journals (45)

Canha-Gouveia A., Costa-Pinto A. R., Martins A., Silva N. A., Faria S., Sousa R. A., Salgado A. J., Sousa N., Reis R. L., and Neves N. M., "Hierarchical scaffolds enhance osteogenic differentiation of human Wharton’s Jelly derived Stem Cells", Biofabrication, vol. 7, issue 3, pp. 035009, doi:10.1088/1758-5090/7/3/035009, 2015.

RepositoriUM

Yan L. P., Salgado A. J., Oliveira J. M., Oliveira A. L., and Reis R. L., "De novo bone formation on macro/microporous silk and silk/nano-sized calcium phosphate scaffolds", Journal of Bioactive and Compatible Polymers, vol. 28, issue 5, pp. 439-452, doi:0.1177/0883911513503538, 2013.

RepositoriUM

Ribeiro-Samy S. M., Silva N. A., Correlo V. M., Fraga J. S., Pinto L. A., Teixeira-Castro A., Leite-Almeida H., Almeida A., Gimble J. M., Sousa N., Salgado A. J., and Reis R. L., "Development and Characterization of a PHB-HV-based 3D Scaffold for a Tissue Engineering and Cell-therapy Combinatorial Approach for Spinal Cord Injury Regeneration", Macromolecular Bioscience, doi:10.1002/mabi.201300178, 2013.

RepositoriUM

Fraga J. S., Silva N. A., Lourenço A. S., Gonçalves V., Neves N. M., Reis R. L., Rodrigues A. J., Manadas B., Sousa N., and Salgado A. J., "Unveiling the effects of the Secretome of Mesenchymal Progenitors from the Umbilical Cord in Different Neuronal Cell Populations", Biochemie, vol. 95, issue 12, pp. 2297-2303, doi:10.1016/j.biochi.2013.06.028, 2013.

RepositoriUM

Silva N. A., Gimble J. M., Sousa N., Reis R. L., and Salgado A. J., "Modulation of Bone Marrow Mesenchymal Stem Cell Secretome by ECM-Like Hydrogels.", STEM CELLS AND DEVELOPMENT olume 22, Number 8, 2013, vol. 22, issue 8, pp. 1232-1240, doi: doi: 10.1089/scd.2012.0524, 2013.

Pojo M., Cerqueira S. R., Mota T., Xavier-Magalhães A., Oliveira J. M., Samy S. M., Mano J. F., Reis R. L., Costa B. M., Sousa N., and Salgado A. J., "In vitro evaluation of the cytotoxicity and cellular uptake of CMCht/PAMAM dendrimer nanoparticles by glioblastoma cell models", Journal of Nanoparticle Research (NANO), doi:10.1007/s11051-013-1621-6, 2013.

RepositoriUM

Cerqueira S. R., Oliveira J. M., Silva N. A., Leite-Almeida H., Samy S. M., Almeida A., Mano J. F., Sousa N., Salgado A. J., and Reis R. L., "Microglia response and in vivo therapeutic potential of methylprednisolone-loaded dendrimer nanoparticles in spinal cord injury", Small, vol. 9, issue 5, pp. 738-749, 2013.

RepositoriUM

Oliveira A. L., Sousa E. C., Silva N. A., Sousa N., Salgado A. J., and Reis R. L., "Peripheral mineralization of a 3D biodegradable tubularconstruct as a way to enhance guidance stabilization in spinal cord injury regeneration", Journal of Materials Science: Materials in Medicine, doi:10.1007/s10856-012-4741-0, 2012.

RepositoriUM

Silva-Correia J., Miranda-Gonçalves V., Salgado A. J., Sousa N., Oliveira J. M., Reis R. M., and Reis R. L., "Angiogenic potential of gellan gum-based hydrogels for application in nucleus pulposus regeneration: In vivo study", Tissue Engineering Part A, vol. 18, issue 11-12, pp. 1203-1212, doi:10.1089/ten.TEA.2011.0632, 2012.

RepositoriUM

Silva N. A., Sousa R. A., Pires A. O., Sousa N., Salgado A. J., and Reis R. L., "Interactions Between Schwann and Olfactory Ensheathing Cells with a Starch/Polycaprolactone Scaffold aimed at Spinal Cord Injury Repair", Journal of Biomedical Materials Research Part A, vol. 100A, issue 2, pp. 470-476, 2011.

Pereira V. H., Salgado A. J., Oliveira J. M., Cerqueira S. R., Frias A. M., Fraga J. S., Roque S., Falcão A. M., Marques F. M., Neves N. M., Mano J. F., Reis R. L., and Sousa N., "In Vivo Biodistribution of Carboxymethylchitosan/Poly(amidoamine) Dendrimer Nanoparticles in Rats", Journal of Bioactive and Compatible Polymers, vol. 26, issue 6, pp. 619–627, 2011.

Pereira D. R., Silva-Correia J., Caridade S. G., Oliveira J. T., Sousa R. A., Salgado A. J., Oliveira J. M., Mano J. F., Sousa N., and Reis R. L., "Development of Gellan-Gum based Microparticles/Hydrogel Matrices for Application in the Intervertebral Disc Regeneration", Tissue Engineering Part C: Methods, vol. 17, issue 10, pp. 961-972, doi:10.1089/ten.TEC.2011.0115, 2011.

Cerqueira S. R., Silva B. L., Oliveira J. M., Mano J. F., Sousa N., Salgado A. J., and Reis R. L., "Multifunctionalized CMCht/PAMAM Dendrimer Nanoparticles Modulate theCellular Uptake by Astrocytes and Oligodendrocytes in Primary Cultures of Glial Cells", Macromolecular Bioscience, vol. 12, pp. 591–597, doi:10.1002/mabi.201100294, 2011.

Baran E. T., Tuzlakoglu K., Salgado A. J., and Reis R. L., "Microchannel-patterned and heparin micro-contact-printed biodegradable composite membranes for tissue-engineering applications", Journal of Tissue Engineering and Regenerative Medicine, vol. 5, pp. 108-114., 2011.

Salgado A. J., Oliveira J. M., Pirraco R. P., Pereira V. H., Fraga J. S., Marques A. P., Neves N. M., Mano J. F., Reis R. L., and Sousa N., "Carboxymethyl-chitosan/Poly(amidoamine) Dendrimer Nanoparticles in Central Nervous System Regenerative Medicine: Effects on Neurons/Glial Cells Viability and Internalization efficiency", Macromolecular Bioscience, vol. 10, issue 10, pp. 1130-1140, 2011.

Ribeiro C. A., Salgado A. J., Fraga J. S., Silva N. A., Reis R. L., and Sousa N., "The Secretome of Bone Marrow Mesenchymal Stem Cells Conditioned Media Varies with Time and Drives a Distinct Effect on Mature Neurons and Glial Cells(Primary Cultures)", Journal of Tissue Engineering and Regenerative Medicine, 2010.

Salgado A. J., Fraga J. S., Mesquita A. R., Neves N. M., Reis R. L., and Sousa N., "Role of human cord mesenchymal progenitors conditioned media in neuronal/glial cell densities, viability, and proliferation", Stem Cells And Development, doi:10.1089/scd.2009.0279., 2010.

Oliveira J. T., Correlo V. M., Sol P. C., Costa-Pinto A. R., Malafaya P. B., Salgado A. J., Bhattacharya M., Charbord P., Neves N. M., and Reis R. L., "Assessment of the Suitability of Chitosan/PolyButylene Succinate Scaffolds Seeded with Mouse Mesenchymal Progenitor Cells for a Cartilage Tissue Engineering Approach", Tissue Engineering - Part A , vol. 14, issue 10, pp. 1651-1661, 2010.

Silva N. A., Salgado A. J., Sousa R. A., Oliveira J. T., Pedro A. J., Leite-Almeida H., Cerqueira R., Almeida A., Mastronardi F., Mano J. F., Neves N. M., Sousa N., and Reis R. L., "Development and characterization of a novel hybrid tissue engineering-based scaffold for spinal cord injury repair", Tissue Engineering Part A, vol. 16, issue 1, pp. 45-54, 2010.

Pereira V. H., Cerqueira S. R., Fraga J. S., Oliveira J. M., Mano J. F., Salgado A. J., Reis R. L., and Sousa N., "Dose dependent effects of FITC-labeled CMC/PAMAM dendrimer nanoparticles on central nervous system derived cells: In vitro and in vivo evaluation", Tissue Engineering and Regenerative Medicine, vol. 6, issue 12, pp. S119, 2009.

Salgado A. J., Sousa R. A., Fraga J. S., Pego J. M., Silva B. A., Malva J. O., Neves N. M., Reis R. L., and Sousa N., "Effects of Starch/ Polycaprolactone-based Blends for Spinal Cord Injury Regeneration in Neurons/Glial Cells Viability and Proliferation", Journal of Bioactive and Biocompatible Polymers, vol. 24, pp. 235-247, 2009.

Costa-Pinto A. R., Salgado A. J., Correlo V. M., Sol P. C., Bhattacharya M., Charbord P., Reis R. L., and Neves N. M., "Adhesion, proliferation, and osteogenic differentiation of a mouse mesenchymal stem cell line (BMC9) seeded on novel melt-based chitosan/polyester 3D porous scaffolds", Tissue Engineering Part A, vol. 14, issue 6, pp. 1049-1057, 2008.

Ribeiro C. A., Salgado A. J., Fraga J. S., Neves N. M., Gimble J. M., Reis R. L., and Sousa N., "A comparative study on the effects of adipose tissue derived and bone marrow mesenchymal stem cells on neurons/glial cells viability, proliferation and differentiation", Tissue Engineering Part A, vol. 14, issue 5, pp. 800-801, 2008.

Salgado A. J., Fraga J. S., Neves N. M., Reis R. L., and Sousa N., "Human umbilical cord perivascular cells (HUCPVCs) as source of mesenchymal progenitors for central nervous system regenerative medicine: Role of paracrine factors and direct cell-to-cell contacts in neurons/glial cells viability, proliferation and differe", Tissue Engineering, vol. 13, issue 7, pp. 1707-1707, 2008.

Tuzlakoglu K., Bolgen N., Salgado A. J., Gomes M. E., Piskin E., and Reis R. L., "Nano- and micro-fiber combined scaffolds: A new architecture for bone tissue engineering", Journal of Materials Science-Materials in Medicine, vol. 16, issue 12, pp. 1099-1104, 2008.

Salgado A. J., Sousa R. A., Oliveira J. T., Silva N. A., Neves N. M., Reis R. L., and Sousa N., "Novel tissue engineering 3D scaffolds for spinal cord injury based on starch/polycaprolactone blends: Development and preliminary assessment of their biological performance", Tissue Engineering, vol. 13, issue 7, pp. 1736-1737, 2008.

Salgado A. J., Gomes M. E., Chou A. M., Coutinho O. P., Reis R. L., and Hutmacher D. W., "Preliminary study on the adhesion and proliferation of human osteoblasts on starch-based scaffolds", Materials Science & Engineering C-Biomimetic and Supramolecular Systems, vol. 20, issue 1-2, pp. 27-33, 2008.

Silva N. A., Salgado A. J., Sousa R. A., Oliveira J. T., Neves N. M., Mano J. F., Sousa N., and Reis R. L., "Starch/gellan gum hybrid 3D guidance systems for spinal cord injury regeneration: Scaffolds processing, characterization and biological evaluation", Tissue Engineering Part A, vol. 14, issue 5, pp. 779-779, 2008.

Salgado A. J., Fraga J. S., Neves N. M., Reis R. L., and Sousa N., "Role of paracrine factors released by mesenchymal progenitors from the umbilical cord in neurons/glial cell viability, proliferation and differentiation", Tissue Engineering Part A, vol. 14, issue 5, pp. 695-695, 2008.

Salgado A. J., Coutinho O. P., Reis R. L., and Davies J. E., "In vivo response to starch-based scaffolds designed for bone tissue engineering applications", Journal of Biomedical Materials Research Part A, vol. 80A, issue 4, pp. 983-989, 2007.

Salgado A. J., Coutinho O. P., Reis R. L., and Davies J. E., "In Vivo Response to Starch Based Scaffolds for Bone Tissue Engineering Applications", Journal of Biomedical Materials Research part A, vol. 80, issue 4, pp. 983-989, 2007.

Salgado A. J., Oliveira J. T., Pedro A. J., and Reis R. L., "Adult Stem Cells in Bone and Cartilage Tissue Engineering ", Current Stem Cell Research & Therapy , vol. 1, issue 20, pp. 345-364, 2006.

Salgado A. J., Figueiredo J. E., Coutinho O. P., and Reis R. L., "Biological response to pre-mineralized starch based scaffolds for bone tissue engineering", Journal of Materials Science-Materials in Medicine, vol. 16, issue 3, pp. 267-275, 2005.

Salgado A. J., Figueiredo J. E., Coutinho O. P., and Reis R. L., "Biological Response to Pre-Mineralized Starch Based Scaffolds for Bone Tissue Engineering", Materials Science: Materials in Medicine, vol. 16, issue 3, pp. 267-275, 2005.

Salgado A. J., Ming Y., Mano J. F., and Reis R. L., "Influence of PLLA Molecular Weight and Cristalinity on the Adhesion and Proliferation of Human Osteoblast Like Cells", Materials Science Forum, vol. 514-16, pp. 1020-1024, 2005.

Tuzlakoglu K., Bolgen N., Salgado A. J., Gomes M. E., Piskin E., and Reis R. L., "Nano- and micro-fiber combined scaffolds: A new architecture for bone tissue engineering", Journal of Material Science: Materials in Medicine, vol. 16, pp. 1099-1104, 2005.

Salgado A. J., Coutinho O. P., and Reis R. L., "Bone tissue engineering: State of the art and future trends", Macromolecular Bioscience, vol. 4, issue 8, pp. 743-765, 2004.

Baran E. T., Tuzlakoglu K., Salgado A. J., and Reis R. L., "Multichannel mould processing of 3D structures from microporous coralline hydroxyapatite granules and chitosan support materials for guided tissue regeneration/engineering", Journal of Materials Science-Materials in Medicine, vol. 15, issue 2, pp. 161-165, 2004.

Salgado A. J., Coutinho O. P., and Reis R. L., "Novel starch-based scaffolds for bone tissue engineering: Cytotoxicity, cell culture, and protein expression", Tissue Engineering, vol. 10, issue 3-4, pp. 465-474, 2004.

Salgado A. J., Coutinho O. P., and Reis R. L., "Novel Starch Based Scaffolds for Bone Tissue Engineering: Cytotoxicity, Cell Culture and Protein Expression", Tissue Engineering, vol. 10, issue 3-4, pp. 665-674, 2004.

Baran E. T., Tuzlakoglu K., Salgado A. J., and Reis R. L., "Multichannel mould processing of 3D structures from porous coralline hydroxyapatite granules and chitosan support material for tissue regeneration/engineering", Journal of Materials Science:Materials in Medicine, vol. 15, pp. 161-165, 2004.

Endres M., Hutmacher D. W., Salgado A. J., Kaps C., Ringe J., Reis R. L., Sittinger M., Brandwood A., and Schantz J. T., "Osteogenic induction of human bone marrow-derived mesenchymal progenitor cells in novel synthetic polymer-hydrogel matrices", Tissue Engineering, vol. 9, issue 4, pp. 689-702, 2003.

Endres M., Hutmacher D. W., Salgado A. J., Kaps C., Ringe J., Reis R. L., Sittinger M., Brandwood A., and Schantz J. T., "Osteogenic Induction of Human Bone Marrow Derived Mesenchymal Progenitor Cells in Novel Synthetic Polymer/Hydrogel Matrices", Tissue Engineering, vol. 9, issue 4, pp. 689-702, 2003.

Salgado A. J., Gomes M. E., Chou A. M., Coutinho O. P., Reis R. L., and Hutmacher D. W., "Preliminary Study on the Adhesion and Proliferation of Human Osteoblasts on Starch Based Scaffolds", Materials Science and Engineering C, vol. 20, issue 1-2, pp. 27-33, 2002.

Review Paper (2)

Salgado A. J., Oliveira J. M., Matins A., Teixeira F. G., Silva N. A., Neves N. M., Reis R. L., and Sousa N., "Tissue Engineering and Regenerative Medicine: Past, Present, and Future", Int Rev Neurobiol., vol. 108, pp. 11-33, 2013.

RepositoriUM

Oliveira J. M., Salgado A. J., Sousa N., Mano J. F., and Reis R. L., "Dendrimers and Derivatives as a Potential Therapeutic Tool in Regenerative Medicine Strategies - A Review", Progress in Polymer Science , vol. 35, issue 9, pp. 1163-1194, doi:10.1016/j.progpolymsci.2010.04.006, 2012.

RepositoriUM

Book Chapter (10)

Salgado A. J., Oliveira J. M., Martins A., Teixeira F. G., Silva N. A., Neves N. M., Sousa N., and Reis R. L., "Tissue Engineering and Regenerative Medicine: Past, Present, and Future", Tissue Engineering of the Peripheral Nerve: Stem Cells and Regeneration Promoting FactorsAcademic Press, Eds. Geuna S., Perroteau I., Tos P., and Battiston B., Academic Press, vol. 108, pp. 1-33, doi:10.1016/B978-0-12-410499-0.00001-0, 2013.

Salgado A. J., Silva N. A., Neves N. M., Reis R. L., and Sousa N., "Hydrogel Based Systems for Spinal Cord Injury Regeneration", Handbook of Natural-based Polymers for Biomedical Applications, Reis RL, Cambridge, pp. in press, 2007.

Salgado A. J., Gomes M. E., Coutinho O. P., and Reis R. L., "Bone and Articular Cartilage Tissue Engineering: The Biological Components", Biodegradable Systems in Medical Functions: Design, Processing, Testing and Applications, Eds. Reis R. L., and Roman J. S., CRC Press LLC, pp. 205-222, 2007.

Salgado A. J., Wang Y., Mano J. F., and Reis R. L., "Influence of molecular weight and cristallinity of poly(L-lactic acid) on the adhesion and proliferation of human osteoblast like cells", Advanced Materials Forum Iii, Pts 1 and 2, pp. 1020-1024, 2006.

Azevedo H. S., Gomes M. E., Malafaya P. B., Marques A. P., Salgado A. J., and Reis R. L., "Natural Origin Degradable Polymers in Biomedical Applications", Handbook of Biodegradable Polymeric Materials and Their Applications, American Scientific Publishers, California, pp. 13-31, 2006.

Gomes M. E., Salgado A. J., and Reis R. L., "Tissue Engineering of Mineralized Tissues: The Essential Elements", Learning From Nature How To Design New Implantable Materials: From Biomineralization Fundamentals To, Kluwer Press, Drodercht , pp. 205-222, 2004.

Malafaya P. B., Gomes M. E., Salgado A. J., and Reis R. L., "Polymer based scaffolds and carriers for bioactive agents from different natural origin materials", Tissue Engineering, Stem Cells and Gene Therapies, pp. 201-233, 2003.

Salgado A. J., Gomes M. E., Coutinho O. P., and Reis R. L., "Isolation and Osteogenic Differentiation of Bone Marrow Progenitor Cells for Application in Tissue Engineering", Methods in Tissue Engineering, The Humana Press Inc, Totowa, pp. 123-130, 2003.

Gomes M. E., Salgado A. J., and Reis R. L., "Bone Tissue Engineering Using Starch Based Scaffolds Obtained by Different Methodologies", NATO/ASI Series, Kluwer Press, Drodercht , pp. 221-249, 2002.

Invited Review Paper (2)

Salgado A. J., Oliveira J. T., Pedro A. J., and Reis R. L., "Adult Stem Cells for Bone and Cartilage Tissue Engineering", Current Stem Cell Research and Therapy, vol. 1, issue 3, pp. 345-364, 2006.

Salgado A. J., Coutinho O. P., and Reis R. L., "Bone Tissue Engineering: State of the Art and Future Trends", Macromolecular Biosciences, vol. 4, pp. 743-765, 2004.

Invited Lecture (4)

Cerqueira S. R., Oliveira J. M., Mano J. F., Sousa N., Salgado A. J., and Reis R. L., "Regeneration Strategies in the Central Nervous System", 3rd 3B´s Symposium on Biomaterials and Stem cells in Regenerative Medicine, 2013.

RepositoriUM

Cerqueira S. R., Oliveira J. M., Salgado A. J., Sousa N., and Reis R. L., "Nanoparticle-mediated drug delivery systems for spinal cord injury repair", Miami Project Lecture Series, The Miami Project To Cure Paralysis, Miller School of Medicine, University of Miami, 2012.

Oliveira J. M., Cerqueira S. R., Salgado A. J., Sousa N., Mano J. F., and Reis R. L., "Dendrimeric nanocarriers for intracellular cell- and tissue-engineering applications", 2nd IBB Meeting, University of Minho, 2010.

Salgado A. J., Neves N. M., Reis R. L., and Sousa N., "Adult Stem Cells and Biomaterials in Central Nervous Regenerative Medicine", 2nd Conference in Biotechnology, 2007.

Conference Abstract -ISI Web of Science Indexed (9)

Cerqueira S. R., Oliveira J. M., Silva B. L., Silva N. A., Mano J. F., Sousa N., Salgado A. J., and Reis R. L., "Intracellular delivery of methylprednisolone by dendrimer-based nanoparticles improves the locomotor outcomes after spinal cord injury", Journal of Tissue Engineering and Regenerative Medicine, vol. 6, issue Suppl.2, pp. 19-19, doi:10.1002/term.1608, 2012.

RepositoriUM

Cerqueira S. R., Pereira V. H., Oliveira J. M., Sousa N., Salgado A. J., and Reis R. L., "Biodistribution and preliminary therapeutic potential of CMCht/PAMAM dendrimer nanoparticles administration in rats", Journal of Tissue Engineering and Regenerative Medicine, vol. 6, issue Suppl.1, pp. 88, doi:10.1002/term.1586, 2012.

RepositoriUM

Silva B. L., Cerqueira S. R., Fevereiro J. P., Pirraco R. P., Marques A. P., Oliveira J. M., Reis R. L., Sousa N., and Salgado A. J., "Hyaluronic acid/poly(amidoamine) dendrimer nanoparticles for central nervous system applications: In vitro and in vivo studies", Journal of Tissue Engineering and Regenerative Medicine, vol. 6, issue Suppl.1, pp. 361-361, doi:10.1002/term.1586, 2012.

RepositoriUM

Teixeira F. G., Carvalho M. M., Silva N. A., Marques F., Mesquita S. D., Neves N. M., Reis R. L., Pinto L., Sousa N., and Salgado A. J., "Using the secretome of mesenchymal progenitors of the umbilical cord as a modulator of neural and glial survival, viability and differentiation", Journal of Tissue Engineering and Regenerative Medicine, vol. 6, issue Suppl. 1, pp. 281-282, doi:10.1002/term.1586, 2012.

RepositoriUM

Cerqueira S. R., Oliveira J. M., Mano J. F., Salgado A. J., Sousa N., and Reis R. L., "Intracellular Methylprednisolone Release to Glial Cells Using An Engineered Dendrimer Nanoparticle System", The International Journal of Artificial Organs, vol. 34, issue 8, pp. 639, 2011.

Cerqueira S. R., Oliveira J. M., Mano J. F., Sousa N., Salgado A. J., and Reis R. L., "Dendrimer-based nanoparticle delivery system for the sustained and intracellular delivery of methylprednisolone to CNS cells: potential application in spinal cord injury treatment", Histology and Histopathology, vol. 26, issue supplement1, pp. 323-324, 2011.

Oliveira J. M., Salgado A. J., Pirraco R. P., Pereira V. H., Fraga J. S., Marques A. P., Neves N. M., Mano J. F., Sousa N., and Reis R. L., "In Vitro Characterization on the Interactions Between Carboxymethyl-chitosan/Poly(amidoamine) Dendrimer Nanoparticles and Neurons/Glial Cells", Tissue Engineering: Part A, vol. 14, pp. 744, 2010.

Cerqueira S. R., Oliveira J. M., Mano J. F., Sousa N., Salgado A. J., and Reis R. L., "Cell targeted nano-based drug delivery systems for spinal cord injury regeneration", Tissue Engineering and Regenerative Medicine, vol. 6, issue 12, pp. S82, 2009.

Martins A. M., Salgado A. J., Azevedo H. S., Leonor I. B., and Reis R. L., "Lysozyme incorporation in biomimetic coated chitosan scaffolds: Development and behaviour in contact with osteoblastic-like cells", Tissue Engineering, vol. 12, issue 4, pp. 1018-1019, 2006.

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