Phenolic compounds: analysis by HPLC

In this entry, the main parameters related to phenolics chemistry and analysis by chromatography are
discussed. The most used extractive techniques, such as solid-phase extraction (SPE) and matrix solid-phase
dispersion (MSPD), will be referred and compared. In addition, the most relevant analytical approaches,
including high-performance liquid chromatography–diode-array detector (HPLC–DAD), LC–mass spectrometry
(LC–MS), and LC–nuclear magnetic resonance (LC–NMR), will be presented, focusing on the
advantages and disadvantages of each method.