A new route to produce starch-based fiber mesh scaffolds by wet spinning and subsequent surface modification as a way to improve cell attachment and proliferation

last updated: 2017-03-07
TitleA new route to produce starch-based fiber mesh scaffolds by wet spinning and subsequent surface modification as a way to improve cell attachment and proliferation
Publication TypePapers in Scientific Journals
Year of Publication2009
AuthorsTuzlakoglu K., Pashkuleva I., Rodrigues M. T., Gomes M. E., van Lenthe G. H., Muller R., and Reis R. L.
Abstract

This study proposes a new route for producing
fiber mesh scaffolds from a starch–polycaprolactone
(SPCL) blend. It was demonstrated that the scaffolds with
77% porosity could be obtained by a simple wet-spinning
technique based on solution/precipitation of a polymeric
blend. To enhance the cell attachment and proliferation,
Ar plasma treatment was applied to the scaffolds. It was
observed that the surface morphology and chemical composition
were significantly changed because of the etching
and functionalization of the fiber surfaces.

JournalJ Biomed Mater Res
Volume92A
Pagination369–377
Date Published2009-12-10
Keywordsbiodegradable fiber, bone tissue engineering;
RightsopenAccess
Peer reviewedno
Statuspublished

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