Vascularization in skin wound healing: where do we stand and where do we go?,

last updated: 2021-12-20
ProjectECM_INK :: publications list
TitleVascularization in skin wound healing: where do we stand and where do we go?,
Publication TypePapers in Scientific Journals
Year of Publication2022
AuthorsMoreira H. R., and Marques A. P.

Cutaneous healing is a highly complex process that, if altered due to, for example, impaired vascularization, results in chronic wounds or repaired neotissue of poor quality. Significant progress has been achieved in promoting neotissue vascularization during tissue repair/regeneration. In this review, we discuss the strategies that have been explored and how each one of them contributes to regulate vascularization in the context of cutaneous wound healing from two different perspectives — biomaterial-based and a cell-based approaches. Finally, we discuss the implications of these findings on the development of the ‘next generation’ approaches to target vascularization in wound healing highlighting the importance of going beyond its contribution to regulate vascularization and take into consideration the temporal features of the healing process and of different types of wounds.

JournalCurrent Opinion in Biotechnology
Date Published2022-02-01
PublisherVolume 73, February 2022, Pages 253-262
Keywordsvascularization, Wound healing
Peer reviewedyes

Back to top