Silk fibroin nanofibers and their blends for skin tissue engineering applications

last updated: 2024-06-19
TitleSilk fibroin nanofibers and their blends for skin tissue engineering applications
Publication TypeBook Chapter
Year of Publication2024
AuthorsAlizadeh S., Simorgh S., Panneerselvam P., Chauhan N. P. S., Kundu S. C., and Gholipourmalekabadi M.
EditorsKundu S. C., and Reis R. L.
Abstract Text

Silk fibroin (SF) nanofibers and their blends are one of the promising materials for wound repair in skin tissue engineering. Well-known biomaterials such as collagen, gelatin, and chitosan have already been investigated in this area. Work on SF scaffolds, including blends with other materials, has the potential to lead to beneficial treatments. The use of specific composite SF scaffolds can cure specific wound problems. Since cells more readily transfer onto the scaffold to facilitate the reconstruction of the endogenous extracellular matrix (ECM), SF paired with a naturally existing ECM component would likely aid the proliferation and/or maturation phases of wound healing. This chapter details silk protein, SF, and its properties and fabrication via electrospinning. Furthermore, SF-based fibrous scaffolds for wound healing and other tissue healing applications are explored.

Book TitleSilk-Based Biomaterials for Tissue Engineering, Regenerative and Precision Medicine (Second Edition)
Pagination445-476
Date2024-01-25
PublisherWoodhead Publishing Series in Biomaterials
ISBN 9780323960175
DOI10.1016/B978-0-323-96017-5.00024-8
URLhttps://www.sciencedirect.com/science/article/abs/pii/B9780323960175000248
KeywordsSilk Fibroin, skin tissue engineering, Wound repair
RightsrestrictedAccess
Peer reviewedyes
Statuspublished

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