PRP Therapy

last updated: 2018-10-17
ProjectFROnTHERA :: publications list
TitlePRP Therapy
Publication TypeBook Chapter
Year of Publication2018
AuthorsCengiz I. F., Oliveira J. M., and Reis R. L.
EditorsOliveira J. M., Pina S., Reis R. L., and Roman J. S.
Abstract Text

Osteochondral lesions remain as a clinical challenge despite the advances in orthopedic regenerative strategies. Biologics, in particular, platelet-rich plasma, has been applied for the reparative and regenerative effect in many tissues, and osteochondral tissue is not an exception. Platelet-rich plasma is an autologous concentrate prepared from the collected blood; thus, this safe application is free of immune response or risk of transmission of disease. It has a high potential to promote regeneration, thanks to its content, and can be applied alone or can reinforce a tissue engineering strategy. The relevant works making use of platelet-rich plasma in osteochondral lesions are overviewed herein. The practical success of platelet-rich plasma is uncertain since there are many factors involved including but not limited to its preparation and administration method. Nevertheless, today, the issues and challenges of platelet-rich plasma have been well acknowledged by researchers and clinicians. Thus, it is believed that a consensus will be built it, and then with high-quality randomized controlled trials and standardized protocols, the efficacy of platelet-rich plasma therapy can be better evaluated.

Book TitleOsteochondral Tissue Engineering
KeywordsOsteochondral, Platelet-Rich Plasma, regeneration, Tissue engineering
Peer reviewedno

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