Project | MagTT :: publications list |
Title | Oxygen conditioning effect on an in vitro co-culture model of tendon-to-bone interface |
Publication Type | Conference Abstract -ISI Web of Science Indexed |
Year of Publication | 2019 |
Authors | Calejo I., Costa-Almeida R., Reis R. L., and Gomes M. E. |
Abstract | Tendon-to-bone interface comprises a heterotypic cellular niche. The native interface is hypovascular, suggesting that the junction is physiologically hypoxic. As it bridges tendon and bone, which require different oxygen concentrations, a tight coordination of different oxygen concentrations along the junction must be considered when trying to mimic and understand biological events occurring within the tissue. Herein, an optimized in vitro co-culture model of tendon-derived cells (hTDCs) and pre-osteoblasts (pre-OBs) [1] was used to study the effect of a restricted oxygen environment on cell behavior. |
Journal | European Cells & Materials Conferences |
Conference Name | ERMIS European Chapter Meeting 2019 |
Date Published | 2019-09-01 |
Conference Location | Rhodes, Greece |
ISSN | 123 |
URL | https://www.ecmconferences.org/abstracts/2019/Collection3/c3.html |
Keywords | co-culture models, hypoxia |
Rights | openAccess |
Peer reviewed | yes |
Status | published |