Outlook in tissue-engineered magnetic systems and biomagnetic control

The advancement of tissue engineering strategies has opened up new therapeutic avenues in the regeneration of many musculoskeletal tissues and cell niches. The burst of research in nanotechnology associated with tissue engineering brings inputs for the precise control of cells and cellular environments, that can play an important role in the development of these new therapies.

Magnetic actuation, especially in combination with magnetic nanoparticles, may be a valuable tool in the interaction with living systems, such as stem cell guidance, retention, stimula- tion, and differentiation. Advances in the field of magnetic technology have also enabled the fabrication of increasingly complex systems such as cell sheets, organoids, or bioprinted scaffolds. Our Opinion article highlights this promising field of research and attempts to cover some of the most recent con- tributions to both tissue engineering and regenerative medicine.