Natural Polyphenols as Modulators of the Fibrillization of Islet Amyloid Polypeptide

last updated: 2020-08-06
ProjectPATH - Programa de Doutoramento Norte 2020 :: publications list
TitleNatural Polyphenols as Modulators of the Fibrillization of Islet Amyloid Polypeptide
Publication TypeBook Chapter
Year of Publication2020
AuthorsAraújo A. R., Reis R. L., and Pires R. A.
EditorsChun H., Reis R. L., Motta A., and Khang G.
Abstract Text

Diabetes mellitus type 2 (type-2 diabetes) is a metabolic disorder characterized by the increased blood glucose concentration and insulin resistance in peripheral tissues (e.g., muscles and adipose tissue). The initiation of the pathological cascade of events that lead to type-2 diabetes has been subject of debate; however, it has been commonly accepted that the oversecretion of human islet amyloid polypeptide (hIAPP, a hormone co-secreted with insulin) by the pancreatic

Book TitleBiomimicked Biomaterials
Volume1250
Pagination159-176
Date2020-06-30
PublisherSpringer, Singapore
ISBN 978-981-15-3261-0
DOI10.1007/978-981-15-3262-7_11
URLhttps://pubmed.ncbi.nlm.nih.gov/32601944/
KeywordsAmylin, Amyloid, Diabetes mellitus type 2, Islet amyloid polypeptide, natural polyphenols, protein aggregation
RightsrestrictedAccess
Peer reviewedyes
Statuspublished

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