Microfluidic systems in cancer research

last updated: 2020-08-31
Project2MATCH :: publications list
TitleMicrofluidic systems in cancer research
Publication TypeBook Chapter
Year of Publication2020
AuthorsCaballero D., Luque-Gonzalez M. A., Reis R. L., and Kundu S. C.
EditorsKundu S. C., and Reis R. L.
Abstract Text

Cancer remains a major burden in our modern society, being the second leading cause of death worldwide. Many efforts are being made to improve our knowledge about the etiology of the disease, its early diagnosis and treatment. Innovative technologies capable of early detection, diagnosis and monitoring the progression of cancer, as well as the efficiency of the therapies, are needed. Microfluidic devices can provide the needed conditions to boost the investigation in cancer theranostics due to their advanced capabilities and versatility. During the last few years, microfluidics systems have been employed in cancer research for the development of in vitro tumor models to investigate the mechanistic determinants of the disease, for drug screening and discovery applications, or for the fabrication of point-of-care devices for pre-clinical uses. Herein, we review the contribution of microfluidics in cancer research, ranging from fundamental research to clinical and industrial applications. We also discuss about the challenges that microfluidic devices must overcome to be adopted by the market and the society, as well as the future directions in cancer research.

Book TitleBiomaterials for 3D tumor modeling
ISBN 9780128181287
Keywordsclinical and industrial applications, Microfluidics, organ-on-chip, tumor models
Peer reviewedno

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