Commercial Products for Osteochondral Tissue Repair and Regeneration.

last updated: 2018-10-17
ProjectHierarchiTech :: publications list
TitleCommercial Products for Osteochondral Tissue Repair and Regeneration.
Publication TypeBook Chapter
Year of Publication2018
AuthorsBicho D., Pina S., Reis R. L., and Oliveira J. M.
EditorsOliveira J. M., Pina S., Reis R. L., and SanRoman J.
Abstract Text

The osteochondral tissue represents a complex structure composed of four interconnected structures, namely hyaline cartilage, a thin layer of calcified cartilage, subchondral bone, and cancellous bone. Due to the several difficulties associated with its repair and regeneration, researchers have developed several studies aiming to restore the native tissue, some of which had led to tissue-engineered commercial products. In this sense, this chapter discusses the good manufacturing practices, regulatory medical conditions and challenges on clinical translations that should be fulfilled regarding the safety and efficacy of the new commercialized products. Furthermore, we review the current osteochondral products that are currently being marketed and applied in the clinical setting, emphasizing the advantages and difficulties of each one.

Book TitleOsteochondral Tissue Engineering. Advances in Experimental Medicine and Biology
PublisherSpringer, Cham
ISBN 978-3-319-76710-9
Keywordsand osteochondral regeneration, cartilage, Commercial products Bone
Peer reviewedno

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