Cell-biomaterials interactions: Mechanical forces assessment by traction force microscopy

last updated: 2023-12-07
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TitleCell-biomaterials interactions: Mechanical forces assessment by traction force microscopy
Publication TypeBook Chapter
Year of Publication2023
AuthorsCaballero D., Reis R. L., and Kundu S. C.
EditorsOliveira J. M., Reis R. L., and Pina S.
Abstract Text

This chapter briefly describes how cell-generated mechanical forces (both by individual cells and multicellular systems) can be measured and quantified in vitro by traction force microscopy (TFM), and discusses their implications in biology. We highlight some of the most relevant works performed in this area of research with particular attention to their applications in musculoskeletal tissue engineering and regenerative medicine. This chapter is meant to provide a quick and concise guide about the use of in vitro tools to quantify mechanical forces, providing a valuable and straightforward resource for researchers for their cell mechanicsebased studies.

Book TitleMultiscale Cell-Biomaterials Interplay in Musculoskeletal Tissue Engineering and Regenerative Medicine
Volume1
Edition1
Chapter8
Pagination181-198
Date2023-11-28
PublisherElsevier
ISBN 9780323972628
DOI10.1016/B978-0-323-91821-3.00002-5
URLhttps://shop.elsevier.com/books/multiscale-cell-biomaterials-interplay-in-musculoskeletal-tissue-engineering-and-regenerative-medicine/oliveira/978-0-323-91821-3
KeywordsMechanical forces, Mechanobiology, Traction force microscopy
RightsrestrictedAccess
Peer reviewedyes
Statuspublished

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