Project | Nature4Health :: publications list |
Title | Approach on chitosan/virgin coconut oil-based emulsion matrices as a platform to design superabsorbent materials |
Publication Type | Papers in Scientific Journals |
Year of Publication | 2020 |
Authors | Silva S. S., Rodrigues, L.C., Fernandes E. M., Gomes J. M., Vilas-Boas A., Pirraco R. P., and Reis R. L. |
Abstract | The design of innovative pharmaceutical products, able to reach unexplored market niches, requires natural materials use with improved swelling and moisture properties. Herein, chitosan (CHT), a natural polymer, was combined with virgin coconut oil (VCO), a resource extracted from coconut kernels, to develop emulsion-based films for biomedical purposes. The film's properties were tuned by changing VCO concentrations, and the structural, morphological, and physical properties of the films were evaluated. The CHT/VCO-based film morphology showed the presence of VCO droplets at different sizes, both in the surface and inner part. Moreover, the capability to develop CHT/VCO-films as superabsorbent materials was shown. The film extracts cytotoxicity was assessed using human adipose stem cells, and metabolic activity was confirmed. The findings suggest that incorporating a small volume of VCO into the CHT system, superabsorbent materials with the potential to be applied in biomedical devices that require high swelling properties, can be developed. |
Journal | Carbohydrate polymers |
Volume | 249 |
Pagination | 116839 |
Date Published | 2020-12-01 |
Publisher | Elsevier |
ISSN | 18791344 |
DOI | 10.1016/j.carbpol.2020.116839 |
URL | https://www.sciencedirect.com/science/article/pii/S0144861720310122 |
Keywords | Biomaterials, Chitosan, emulsion film, natural polymers, skin diseases, Virgin coconut oil |
Rights | restrictedAccess |
Peer reviewed | yes |
Status | published |