Ancient fibrous biomaterials from silkworm protein fibroin and spider silk blends: Biomechanical patterns

last updated: 2024-03-21
ProjectBREAST-IT: Boosting Research Against Solid Tumor-Immunocompetence Tackling :: publications list
TitleAncient fibrous biomaterials from silkworm protein fibroin and spider silk blends: Biomechanical patterns
Publication TypeReview Paper
Year of Publication2022
AuthorsJohari N., Khodaei A., Samadikuchaksaraei A., Reis R. L., Kundu S. C., and Moroni L.
Abstract Text

Silkworm silk protein fibroin and spider silk spidroin are known biocompatible and natural biodegradable polymers in biomedical applications. The presence of β-sheets in silk fibroin and spider spidroin conformation improves their mechanical properties. The strength and toughness of pure recombinant silkworm fibroin and spidroin are relatively low due to reduced molecular weight. Hence, blending is the foremost approach of recent studies to optimize silk fibroin and spidroin's mechanical properties. As summarised in the present review, numerous research investigations evaluate the blending of natural and synthetic polymers. The effects of blending silk fibroin and spidroin with natural and synthetic polymers on the mechanical properties are discussed in this review article. Indeed, combining natural and synthetic polymers with silk fibroin and spidroin changes their conformation and structure, fine-tuning the blends' mechanical properties.

JournalActa Biomaterialia
Volume153
Pagination38-67
Date Published2022-09-17
PublisherElsevier
ISSN1878-7568
DOIhttps://doi.org/10.1016/j.actbio.2022.09.0301878-7568
URLhttps://www.sciencedirect.com/science/article/pii/S1742706122005931?via%3Dihub
KeywordsBLENDS, Mechanical Properties, Silkworm protein fibroin, Spider silk spidroin, Structure
RightsopenAccess
Peer reviewedyes
Statuspublished

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