Tendon stem cell niche

last updated: 2017-01-09
TitleTendon stem cell niche
Publication TypeBook Chapter
Year of Publication2015
AuthorsCosta-Almeida R., Gonçalves A. I., Gershovich P., Rodrigues M. T., Reis R. L., and Gomes M. E.
EditorsTurksen K.
Abstract Text

Tendon stem cells constitute a heterogeneous population of stem and progenitor cells that is involved in tendon formation and healing. The basic understanding of the interactions between tendon cells and their surroundings can enable the development of improved regenerative therapies. In this chapter, the main characteristics of their microenvironment – niche – are reviewed. In particular, the importance of signaling molecules and extracellular matrix (ECM) are highlighted, focusing on their potential role in tendon regeneration. 

Book TitleTissue-Specific Stem Cell Niche
PublisherSpringer Publisher
ISBN 978-3-319-21704-8
KeywordsCell therapy, Extracellular matrix, Niche, regenerative medicine, Tendon healing/repair, Tendon stem/progenitor cells, Tenogenesis
Peer reviewedyes

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