Layer-by-layer deposition of antimicrobial polymers on cellulosic fibers: a new strategy to develop bioactive textiles

last updated: 2014-11-12
TitleLayer-by-layer deposition of antimicrobial polymers on cellulosic fibers: a new strategy to develop bioactive textiles
Publication TypePapers in Scientific Journals
Year of Publication2013
AuthorsGomes A. P., Mano J. F., Queiroz J. A., and Gouveia I. C.
Abstract

In recent years, there has been an increase of infectious diseases caused by different microorganisms and the development of antibiotic resistance. In this way, the search for new and efficient antibacterial materials is imperative. The main polysaccharides currently used in the biomedical and pharmaceutical domains are chitin and its derivative chitosan (CH) and alginates (ALG). In this study, a simple technique of Layer by Layer (LbL) of applying polycation CH and polyanion ALG was used to prepare CH/ALG multilayers on cotton samples via the electrostatic assembly with success. The CH/ALG cotton samples (functionalized) were investigated for their antibacterial properties towards Staphylococcus aureus and Klebsiella pneumonia using the international standard method JIS L 1902:2002. The antibacterial activity of the functionalized samples was tested in terms of bacteriostatic and bactericidal activity, and results showed that the samples exhibited a bacteriostatic effect on the two bacteria tested, as expected. In addition, samples with five layers (CH/ALG/CH/ALG/CH) were more effective in inhibiting bacterial growth. This new coating for cellulosic fibers is a new strategy and may open new avenues for the development of antimicrobial polymers with potential application in health-care field.

JournalPolymers for Advanced Technologies
Volume24
Issue11
Pagination1005 - 1010
Date Published2013-10-18
PublisherJohn Wiley & Sons, Ltd.
DOI10.1002/pat.3176
URLhttp://onlinelibrary.wiley.com/doi/10.1002/pat.3176/abstract
KeywordsALGINATE, Chitosan, cotton, JIS L 1902, LbL
RightsopenAccess
Peer reviewedyes
Statuspublished

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