Hybrid Alginate-Based Cryogels for Life Science Applications

last updated: 2016-08-31
Project Bioresorbable urological stent systems based on natural polymers :: publications list
TitleHybrid Alginate-Based Cryogels for Life Science Applications
Publication TypePapers in Scientific Journals
Year of Publication2016
AuthorsBarros, A. A., Quraishi S., Martins M., GuriKov P., Subrahmanyam R., Smirnova I., Duarte A. R. C., and Reis R. L.
Abstract

This work presents a novel route toward porous scaffolds for tissue engineering and regenerative medicine (TERM) appli- cations. Hybrid cryogels with gelatin, gellan gum, carboxymethylcellulose, and lignin were prepared by a two-step process. Textural properties of the cryogels were analyzed by SEM and micro-computed tomography. The results indicated that rapid freezing retained sample shape and yielded macroporous materials. The mechanical properties of the cryogels were characterized in compression mode. Cytotoxicity studies indicated that the hybrid-alginate cryogels did not present cyto- toxicity and have the potential to be used in TERM. 

JournalChemie Ingenieur Technik
Volume88
Issue11
Pagination0-0
Date Published2016-08-29
PublisherWILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
ISSN1522-2640
DOI10.1002/cite.201600096
URLhttp://onlinelibrary.wiley.com/doi/10.1002/cite.201600096/abstract
KeywordsAlginate-based, co2 gelation, cryogels
RightsrestrictedAccess
Peer reviewedyes
Statuspublished

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