Project | POLARIS :: publications list |
Title | Effect of Melanomal Proteins on Sepia Melanin Assembly |
Publication Type | Papers in Scientific Journals |
Year of Publication | 2015 |
Authors | Srisuk P., Correlo V. M., Leonor I. B., Palladino P., and Reis R. L. |
Abstract | Melanins are phenol-based pigments with the potential for widespread applications including bioelectronics and tissue engineering. The concentration-dependent structural transition of sepia melanin in water is analyzed. This biopolymer at high concentration gives the well-known nanospheres, whereas sample dilution gives unforeseen nanofibres exhibiting the structural features of mature amyloid fibrils. We propose a mechanism of pigment self-assembly dependent on the interaction of residual melanosomal protein(s) with eumelanin heteropolymer. Our results contribute to understanding the peculiar physico-chemical properties of this ubiquitous pigment |
Journal | Journal of Macromolecular Science, Part B: Physics |
Date Published | 2015-10-06 |
Publisher | Taylor and Francis Ltd. |
DOI | 10.1080/00222348.2015.1103430 |
URL | http://www.tandfonline.com/doi/abs/10.1080/00222348.2015.1103430 |
Keywords | amyloid fibrils, atomic force microscopy, cephalopod ink, scanning electron microscopy, Scanning transmission electron microscopy, Sepia melanin self-assembly |
Rights | openAccess |
Peer reviewed | yes |
Status | published |