Title | Combined application of Silk-fibroin/methacrylated gellan gum hydrogel in tissue engineering approaches for partial and/or total meniscus replacement while enabling control of neovascularisation |
Publication Type | Conference Abstract -ISI Web of Science Indexed |
Year of Publication | 2013 |
Authors | Pereira H., Silva-Correia J., Yan L. P., Oliveira A. L., Oliveira J. M., Espregueira-Mendes J. D., and Reis R. L. |
Abstract | Meniscus tissue engineering can benefit from the use of highly developed scaffolds that are able to mimic the anatomy of this complex tissue, i.e. enable controlling the segmental vascularization during tissue regeneration. In this work, novel scaffolds were produced combining a porous silk polymeric matrix at 12 wt% (silk-12) and the methacrylated gellan gum hydrogel (iGG-MA), which was previously shown to be non-angiogenic. A chorioallantoic membrane (CAM) assay was used to investigate the ability of the silk-12/iGG-MA scaffolds to control cell ingrowth, segmental vascularization, and innervations. |
Journal | Revue de Chirurgie Orthopédique et Traumatologique |
Conference Name | Travaux de la Société Française d'Arthroscopie |
Volume | 99 |
Issue | 8 |
Pagination | e18-e19 |
Date Published | 2013-12-01 |
Keywords | meniscus, Silk Fibroin |
Rights | openAccess |
Peer reviewed | yes |
Status | published |