Bioinert, biodegradable and injectable polymeric matrix composites for hard tissue replacement: state of the art and recent developments

last updated: 2014-12-06
TitleBioinert, biodegradable and injectable polymeric matrix composites for hard tissue replacement: state of the art and recent developments
Publication TypePapers in Scientific Journals
Year of Publication2008
AuthorsMano J. F., Sousa R. A., Boesel L. F., Neves N. M., and Reis R. L.
Abstract

The present review paper examines the use of different types of polymeric matrix composites in hard tissue replacement applications.
 The review presents the actual state of the art in the fields of bioinert composites for permanent applications, biodegradable
 matrix composites for temporary applications and the emerging area of injectable composites.In all cases some recent developments
 are also discussed.The paper starts with an introduction to locate the reader. Bone–analogue composites are then extensively
 discussed.Several other systems based on an inert polymeric matrix are described, focusing on their proposed applications.A great
 emphasis is afterwards given to biodegradable matrix systems.The most widely used synthetic bioresorbable systems are analysed
 and compared with an example of natural origin degradable composites–starch based composites.Finally, composite systems that
 are non-processable by melt based routes and in many cases injectable are discussed in detail, including several recent developments
 on this emerging area of research.

JournalComposites Science and Technology
Volume64
Issue6
Pagination789-817
Date Published2008-11-05
KeywordsBiomaterials, Injection moulding, Mechanical Properties, Microstructure, Polymer matrix composites
RightsrestrictedAccess
Peer reviewedyes
Statuspublished

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