@article {20208,
	title = {Biochemical gradients to form a 3-D osteochondral in vitro model},
	booktitle = {TERMIS-EU 2019},
	year = {2019},
	month = {2019-05-30 00:00:00},
	address = {Rhodes, Greece},
	abstract = {<p>Gradients of 3-D complex functional patterns at micro-scale are common in nature [1]. While diverse fabrication techniques based on material science, micro-scale engineering, and microfluidics have been used to synthesize biomimetic and tailored microenvironments [2,3], a great need is still present for improved methods of gradient tissue engineering. Here, we developed the precise spatial control over both cell/tissue phenotype and pre-vasculature formation, which opens-up possibilities for the study of complex tissues interfaces, with broader applications in drug testing and regenerative medicine.</p>},
	keywords = {3D, bioreactor, In Vitro Model, Osteochondral},
	url = {https://termis.org/eu2019/},
	author = {Canadas, R. F. and Ren, T. and Marques, A. P. and Oliveira, J. M. and Reis, R. L. and Demirci, U.}
}
