@article {19917,
	title = {In vivo Performance of HRP-silk fibroin/ZnSr doped β-TCP Scaffolds for Osteochondral Tissue Regeneration },
	booktitle = {15th Bath Biomechanics Symposium},
	year = {2019},
	month = {2019-09-16 00:00:00},
	address = {Bath, UK},
	abstract = {<p>Orthopedic surgeons are facing major limitations in the development of personalized therapies to regenerate the osteochondral (OC) defects.Hierarchically structured scaffolds consisting of cartilaginous and underlying osseous layers have appeared as advanced biomaterials to mimic the OC tissue [1].In this study, we investigated the <em>in vivo</em> performance of hierarchical enzymatically crosslinked silk fibroin (SF) hydrogels combined with ZnSr-doped β-tricalcium phosphate (ZnSrTCP) for OC tissue regeneration. The antibacterial properties of the hierarchical scaffolds were also assessed. Ionic-doped biomaterials can enhance osteogenesis and angiogenesis, and improve their mechanical performance [2].</p>},
	keywords = {bilayered scaffolds, enzymatically crosslinked silk fibroin, ionic-doped tricalcium phosphate, Osteochondral Tissue Engineering},
	author = {Ribeiro, V. P. and Pina, S. and Canadas, R. F. and Araujo, A. and Morais, A. and Vilela, C. and Vieira, S. and Cengiz, I. F. and Reis, R. L. and Oliveira, J. M.}
}
