@article {19309,
	title = {Remotely activation of Activin A type II receptor via magnetic nanoparticles for tendon regeneration strategies},
	booktitle = {25th Annual and Anniversary Meeting of the European Orthopaedic Research Society (EORS)},
	year = {2017},
	month = {2017-09-25 00:00:00},
	address = {Munich},
	abstract = {<p>Tendon injuries are a worldwide problem affecting several age groups and stem cell based therapies hold potential for tendon strategies guiding tendon regeneration.</p>
<p>Tendons rely on mechano-sensing mechanisms that regulate homeostasis and influence regeneration. The mechanosensitive receptors available in cell membranes sense the external stimuli and initiate mechanotransduction processes. Activins are members of the TGF-β superfamily which participate in several tendon biological processes. It is envisioned that the activation of the activin receptor, trigger downstream Smad2/3 pathway thus regulating the transcription of tenogenic genes driving stem cell differentiation.\&nbsp;</p>},
	keywords = {Magnetic nanoparticles, mechanotransduction, Tendon},
	author = {Gon{\c c}alves, A. I. and Rotherham, M. and Markides, H. and Rodrigues, M. T. and Reis, R. L. and Gomes, M. E. and Haj, A. E.}
}
