@article {18595,
	title = {Harnessing magnetic-mechano actuation in regenerative medicine and tissue engineering},
	journal = {Trends in Biotechnology},
	volume = {33},
	year = {2015},
	month = {2015-06-26 00:00:00},
	pages = {471-479},
	publisher = {Cell},
	abstract = {<p style="text-align: justify;">Mechanical stimulus is of upmost importance in tissues\&nbsp;developmental and regeneration processes as well as in\&nbsp;maintaining body homeostasis. Classical physiological\&nbsp;reactions encompass an increase of blood vessel diameter\&nbsp;upon exposure to high blood pressure, or the expansion\&nbsp;of cortical bone after continuous high-impact exercise. At a cellular level, it is well established that\&nbsp;extracellular stiffness, topography, and remote magnetic\&nbsp;actuation are instructive mechanical signals for stem\&nbsp;cell differentiation. Based on this, biomaterials and their\&nbsp;properties can be designed to act as true stem cell\&nbsp;regulators, eventually leading to important advances\&nbsp;in conventional tissue engineering techniques. This review\&nbsp;identifies the latest advances and tremendous\&nbsp;potential of magnetic actuation within the scope of\&nbsp;regenerative medicine and tissue engineering.\&nbsp;</p>},
	keywords = {magnetic actuation, regenerative medicine, Stem cells},
	doi = {10.1016/j.tibtech.2015.06.006},
	url = {http://www.sciencedirect.com/science/article/pii/S0167779915001286},
	author = {Santos, L. and Reis, R. L. and Gomes, M. E.}
}
