@inbook {18371, title = {Tendon stem cell niche}, booktitle = {Tissue-Specific Stem Cell Niche}, year = {2015}, month = {2015-09-01 00:00:00}, pages = {221-244}, publisher = {Springer Publisher}, organization = {Springer Publisher}, abstract = {

Tendon stem cells constitute a heterogeneous population of stem and progenitor cells that is involved in tendon formation and healing. The basic understanding of the interactions between tendon cells and their surroundings can enable the development of improved regenerative therapies. In this chapter, the main characteristics of their microenvironment {\textendash} niche {\textendash} are reviewed. In particular, the importance of signaling molecules and extracellular matrix (ECM) are highlighted, focusing on their potential role in tendon regeneration.\ 

}, keywords = {Cell therapy, Extracellular matrix, Niche, regenerative medicine, Tendon healing/repair, Tendon stem/progenitor cells, Tenogenesis}, isbn = {978-3-319-21704-8}, issn = {2196-8985}, doi = {10.1007/978-3-319-21705-5_10}, url = {http://link.springer.com/chapter/10.1007/978-3-319-21705-5_10}, author = {Costa-Almeida, R. and Gon{\c c}alves, A. I. and Gershovich, P. and Rodrigues, M. T. and Reis, R. L. and Gomes, M. E.}, editor = {Turksen, K.} }